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REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK
(Pathway_1150)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TSC2 1 0.810 -0.710
TSC2 1 0.810 -0.710 -0.715
RHEB 1 2.630 -1.320 0.991 -0.417
PPM1A 0 -0.680 1.340 0.402
PPM1A 0 -0.680 1.340 -1.556 -0.874
PRKAG2 0 1.300 -0.990 0.278 -0.667
PRKAB1 0 0.640 -1.180
STK11 0
PRKAA1 0 0.910 0.060
CAB39 0 -0.920 0.670
RPTOR 0 0.520 -1.030 0.623 0.466
PRKAA2 0 -0.030 -0.350
PRKAA2 0 -0.030 -0.350
TSC1 0 1.100 -0.150
PRKAG1 0 0.400 -0.420 0.278 -0.667
STRADA 0

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CAB39 Ubiquitylation K20 0.992 _NLK(gl)ESMAVLEK_
PPM1A Ubiquitylation K278 -0.176 _VCNEVVDTCLYK(gl)GSR_
PRKAA1 Ubiquitylation K271 -0.536 _ATIK(gl)DIR_
PRKAA1 Ubiquitylation K396 -0.419 _HTLDELNPQK(gl)SK_
PRKAA1 Ubiquitylation K485 -1.326 -1.554 _SIDDEITEAK(gl)SGTATPQR_
PRKAA2 Ubiquitylation K271 -0.536 _ATIK(gl)DIR_
PRKAA2 Phosphorylation S377 -0.020 _MPPLIADS(ph)PK_
PRKAB1 Phosphorylation S108 -0.357 0.129 _S(ph)HNNFVAILDLPEGEHQYK_
PRKAG1 Ubiquitylation K78 -0.588 _AAPLWDSK(gl)K_
PRKAG1 Ubiquitylation K79 -0.588 _AAPLWDSK(gl)K_
PRKAG1 Ubiquitylation K243 -0.525 -0.505 _VSALPVVDEK(gl)GR_
PRKAG2 Ubiquitylation K78 -0.588 _AAPLWDSK(gl)K_
PRKAG2 Ubiquitylation K79 -0.588 _AAPLWDSK(gl)K_
PRKAG2 Ubiquitylation K243 -0.525 -0.505 _VSALPVVDEK(gl)GR_
RHEB Ubiquitylation K121 -0.852 _VQIPIMLVGNKK(gl)_
RPTOR Phosphorylation S722 0.393 1.196 _SVSS(ph)YGNIR_
RPTOR Phosphorylation T857 -0.348 _VLDTSSLT(ph)QSAPAS(ph)PTNK_
RPTOR Phosphorylation S859 -0.462 -0.346 _VLDTSSLTQS(ph)APASPT(ph)NK_
RPTOR Phosphorylation S863 -0.208 -0.001 _VLDTSSLTQS(ph)APAS(ph)PTNK_
RPTOR Phosphorylation T865 -0.317 _VLDTSSLTQS(ph)APASPT(ph)NK_
RPTOR Phosphorylation S877 -0.114 -0.074 _GVHIHQAGGS(ph)PPASSTSSSSLTNDVAK_
RPTOR Ubiquitylation K1008 -0.329 _QAQQVIQK(gl)GITR_
STK11 Phosphorylation S31 0.437 0.073 _IDS(ph)TEVIYQPR_
STK11 Phosphorylation T32 1.256 0.248 _IDS(ph)TEVIYQPR_
STRADA Ubiquitylation K7 -0.518 _(ac)SFLVSK(gl)PER_
TSC1 Phosphorylation S505 0.141 0.350 _GGFDS(ph)PFYR_
TSC2 Ubiquitylation K3 -1.397 _(ac)AK(gl)PTSKDSGLK_
TSC2 Ubiquitylation K14 -1.297 _DSGLKEK(gl)FK_
TSC2 Ubiquitylation K69 0.051 _MIGQICEVAK(gl)TK_
TSC2 Ubiquitylation K71 -0.157 _MIGQICEVAKTK(gl)_
TSC2 Ubiquitylation K258 -0.278 _ELCEPCWK(gl)LMR_
TSC2 Ubiquitylation K634 1.610 _LGLPNK(gl)DGVVR_
TSC2 Phosphorylation S950 -0.152 -0.529 _STS(ph)LNERPK_
TSC2 Phosphorylation S1064 -0.927 _SLLGLDSGELQSGPESSSS(ph)PGVHVR_
TSC2 Phosphorylation S1248 -0.604 _SNTDSAVVMEEGS(ph)PGEVPVLVEPPGLEDVEAALGMDRR_
TSC2 Phosphorylation S1329 -0.120 _S(ph)SSSPELQTLQDILGDPGDK_
TSC2 Phosphorylation S1331 -0.262 _SSS(ph)SPELQTLQDILGDPGDKADVGR_
TSC2 Phosphorylation S1332 -0.063 _SSSS(ph)PELQTLQDILGDPGDK_
TSC2 Phosphorylation S1355 0.174 0.351 _ADVGRLS(ph)PEVK_
TSC2 Phosphorylation S1362 0.859 _S(ph)QSGTLDGESAAWSASGEDSR_
TSC2 Phosphorylation S1364 0.522 0.550 _SQS(ph)GTLDGESAAWSASGEDSR_
TSC2 Phosphorylation T1366 0.137 _SQSGT(ph)LDGESAAWSASGEDSR_
TSC2 Phosphorylation S1396 0.498 _S(ph)PSGLRPR_
TSC2 Phosphorylation S1743 0.596 _RLISS(ph)VEDFTEFV_


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