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Query: SQLE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SQLE 0 -2.488 -0.560 0.410 -1.509 -0.595

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SQLE Ubiquitylation K556 -0.794 _ALLSSGAVLYK(gl)_
SQLE Ubiquitylation K235 -0.829 _K(gl)AAMAEPNAK_
SQLE Ubiquitylation K157 -0.878 _DLK(gl)EPDR_
SQLE Ubiquitylation K90 -2.393 -1.358 _SPPESENK(gl)EQLEAR_
SQLE Ubiquitylation K400 -1.368 _SMPASFLPPSSVKK(gl)_

Background Information for SQLE:


Pubmed-SQLE »
Uniprot-SQLE »
Biogrid-SQLE »
ProteomicsDB-SQLE »

Tumorportal-SQLE »
COSMIC-SQLE »
GenomeRNAi-SQLE »
Genecards-SQLE


Protein-protein Interactions for SQLE
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP2B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRND Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC17A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC18A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMCO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TREML2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SQLE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Pyr_OxRdtase_NAD-bd_dom IPR001327 0.03
Category members mOase_FAD-bd IPR002938 0
Category members Rng_hydrolase-like IPR003042 0
Category members FAD-dep_OxRdtase IPR006076 0


Protein complexes (CORUM database) featuring SQLE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SQLE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0006725 cellular aromatic compound metabolic process Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0016126 sterol biosynthetic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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