Results for the Category
REACTOME_CHOLESTEROL_BIOSYNTHESIS
(Pathway_164)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| HMGCS1 | 1 | -1.450 | 3.080 | -0.209 | 0.030 | |||
| LBR | 1 | -0.600 | 0.310 | 0.658 | 0.471 | |||
| CYP51A1 | 0 | 0.435 | 0.502 | |||||
| MSMO1 | 0 | -0.500 | 0.990 | 0.654 | 0.738 | |||
| IDI1 | 0 | -0.310 | 0.550 | -0.903 | 0.896 | |||
| FDFT1 | 0 | -0.960 | 0.750 | -0.161 | -0.107 | -0.241 | -0.023 | 0.147 |
| SQLE | 0 | -0.560 | 0.410 | -1.509 | -0.595 | |||
| HMGCR | 0 | 0.240 | 0.010 | |||||
| DHCR24 | 0 | 1.100 | -0.830 | 0.024 | -0.083 | |||
| HSD17B7 | 0 | -0.130 | 0.330 | |||||
| TM7SF2 | 0 | 0.370 | 0.040 | 1.044 | ||||
| GGPS1 | 0 | 1.730 | -0.970 | |||||
| LSS | 0 | 1.920 | -0.820 | 0.063 | ||||
| LSS | 0 | 1.920 | -0.820 | 0.985 | 0.835 | |||
| FDPS | 0 | 0.900 | -0.620 | -0.782 | ||||
| MVD | 0 | 0.420 | -0.680 | |||||
| DHCR7 | 0 | -0.384 | 0.267 | 0.288 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| CYP51A1 | Ubiquitylation | K156 | -0.292 | _GVAYDVPNPVFLEQK(gl)K_ | |
| CYP51A1 | Ubiquitylation | K157 | 0.360 | -0.309 | _GVAYDVPNPVFLEQKK(gl)_ |
| CYP51A1 | Ubiquitylation | K266 | 0.573 | _DIFYK(gl)AIQK_ | |
| CYP51A1 | Ubiquitylation | K368 | 0.490 | 0.247 | _CIK(gl)ETLR_ |
| CYP51A1 | Ubiquitylation | K412 | -0.492 | 0.017 | _LK(gl)DSWVER_ |
| CYP51A1 | Ubiquitylation | K436 | -0.295 | -0.462 | _YLQDNPASGEK(gl)FAYVPFGAGR_ |
| DHCR24 | Ubiquitylation | K76 | -0.970 | 0.315 | _VRDIQK(gl)QVR_ |
| DHCR24 | Ubiquitylation | K254 | -0.170 | _GLEAICAK(gl)FTHESQR_ | |
| DHCR24 | Ubiquitylation | K313 | 0.393 | _HVENYLK(gl)TNR_ | |
| DHCR24 | Ubiquitylation | K367 | -0.346 | -0.263 | _ISLLK(gl)LTQGETLR_ |
| DHCR24 | Ubiquitylation | K459 | -0.920 | -0.275 | _QLEK(gl)FVR_ |
| DHCR24 | Ubiquitylation | K496 | -0.539 | -0.460 | _EK(gl)LGCQDAFPEVYDK_ |
| DHCR24 | Ubiquitylation | K509 | -0.754 | _LGCQDAFPEVYDK(gl)ICK_ | |
| DHCR7 | Ubiquitylation | K4 | -0.994 | _(ac)AAK(gl)SQPNIPK_ | |
| DHCR7 | Ubiquitylation | K13 | -0.522 | 0.107 | _AK(gl)SLDGVTNDR_ |
| DHCR7 | Phosphorylation | S14 | 0.877 | 0.606 | _S(ph)LDGVTNDR_ |
| DHCR7 | Ubiquitylation | K88 | -0.930 | -0.171 | _LSDIWAK(gl)TPPITR_ |
| FDFT1 | Ubiquitylation | K41 | -0.022 | _MDQDSLSSSLK(gl)TCYK_ | |
| FDFT1 | Ubiquitylation | K45 | -0.877 | -0.339 | _TCYK(gl)YLNQTSR_ |
| FDFT1 | Ubiquitylation | K115 | -0.424 | _FMESK(gl)EKDR_ | |
| FDFT1 | Ubiquitylation | K213 | -0.200 | _ANSMGLFLQK(gl)TNIIR_ | |
| FDFT1 | Ubiquitylation | K358 | -2.436 | -0.946 | _IPDSDPSSSK(gl)TR_ |
| FDPS | Ubiquitylation | K112 | -0.223 | _LK(gl)EVLEYNAIGGK(gl)YNR_ | |
| FDPS | Ubiquitylation | K123 | -1.471 | -0.469 | _LK(gl)EVLEYNAIGGK(gl)YNR_ |
| FDPS | Ubiquitylation | K210 | 0.306 | _LLK(gl)LYCR_ | |
| FDPS | Ubiquitylation | K332 | -0.588 | _IGTDIQDNK(gl)CSWLVVQCLQR_ | |
| FDPS | Ubiquitylation | K353 | -1.239 | _ATPEQYQILK(gl)ENYGQK_ | |
| FDPS | Ubiquitylation | K359 | -0.930 | -0.120 | _ENYGQK(gl)EAEK(gl)VAR_ |
| FDPS | Ubiquitylation | K363 | 0.237 | -1.039 | _ENYGQK(gl)EAEK(gl)VAR_ |
| GGPS1 | Ubiquitylation | K3 | -0.038 | 0.709 | _(ac)MEK(gl)TQETVQR_ |
| HMGCR | Ubiquitylation | K142 | -0.522 | _ASTLAK(gl)FALSSNSQDEVR_ | |
| HMGCR | Ubiquitylation | K248 | -3.854 | -2.107 | _VLEEEENK(gl)PNPVTQR_ |
| HMGCR | Ubiquitylation | K299 | -1.680 | -0.460 | _VSLGLDENVSK(gl)R_ |
| HMGCR | Ubiquitylation | K363 | -1.750 | _NPITSPVVTQKK(gl)_ | |
| HMGCR | Ubiquitylation | K381 | -0.848 | _NNQK(gl)CDSVEEETGINR_ | |
| HMGCR | Ubiquitylation | K401 | -3.050 | _KVEVIK(gl)PLVAETDTPNR_ | |
| HMGCR | Ubiquitylation | K502 | -1.382 | _K(gl)LSEPSSLQYLPYR_ | |
| HMGCR | Ubiquitylation | K633 | -1.104 | _LQK(gl)LHTSIAGR_ | |
| HMGCR | Ubiquitylation | K662 | -1.291 | _SGDAMGMNMISK(gl)GTEK_ | |
| HMGCR | Ubiquitylation | K704 | -1.716 | _GK(gl)SVVCEAVIPAK(gl)VVR_ | |
| HMGCR | Ubiquitylation | K715 | -1.982 | _SVVCEAVIPAK(gl)VVR_ | |
| HMGCR | Ubiquitylation | K873 | -1.345 | _SK(gl)INLQDLQGACTKK_ | |
| HMGCR | Ubiquitylation | K885 | -1.690 | _SKINLQDLQGACTK(gl)K_ | |
| HMGCR | Ubiquitylation | K886 | -1.325 | _INLQDLQGACTKK(gl)_ | |
| HMGCS1 | Phosphorylation | S4 | -1.161 | -1.052 | _PGS(ph)LPLNAEACWPK_ |
| HMGCS1 | Ubiquitylation | K100 | -0.673 | _LEVGTETIIDK(gl)SK_ | |
| HMGCS1 | Ubiquitylation | K102 | -1.761 | -0.427 | _LEVGTETIIDKSK(gl)_ |
| HMGCS1 | Ubiquitylation | K273 | -0.550 | -0.790 | _LVQK(gl)SLAR_ |
| HMGCS1 | Ubiquitylation | K321 | -0.588 | -0.833 | _AFMK(gl)ASSELFSQK_ |
| HMGCS1 | Ubiquitylation | K330 | -0.934 | _ASSELFSQK(gl)TK_ | |
| HMGCS1 | Ubiquitylation | K332 | -0.326 | _ASSELFSQKTK(gl)_ | |
| HMGCS1 | Ubiquitylation | K409 | -0.898 | _ITASLCDLK(gl)SR_ | |
| HMGCS1 | Ubiquitylation | K428 | -1.720 | _TGVAPDVFAENMK(gl)LR_ | |
| HMGCS1 | Phosphorylation | S495 | -1.763 | -1.842 | _RPTPNDDTLDEGVGLVHSNIATEHIPS(ph)PAKK_ |
| HSD17B7 | Ubiquitylation | K176 | 0.504 | 0.368 | _K(gl)SNFSLEDFQHSK_ |
| HSD17B7 | Ubiquitylation | K321 | -0.534 | 0.412 | _LLELEK(gl)HIR_ |
| HSD17B7 | Ubiquitylation | K329 | 0.319 | 0.113 | _VTIQK(gl)TDNQAR_ |
| IDI1 | Ubiquitylation | K37 | -0.752 | _K(gl)NCHLNENIEK_ | |
| IDI1 | Ubiquitylation | K176 | -0.482 | _SYCYVSK(gl)EELK_ | |
| LBR | Phosphorylation | T58 | 0.988 | -0.034 | _ENDIKPLT(ph)SFR_ |
| LBR | Phosphorylation | S59 | 1.927 | 0.405 | _ENDIKPLTS(ph)FR_ |
| LBR | Phosphorylation | S97 | 0.786 | 0.479 | _RS(ph)ASASHQADIK_ |
| LBR | Phosphorylation | S99 | 0.671 | 0.999 | _SAS(ph)ASHQADIK_ |
| LBR | Phosphorylation | S101 | 0.461 | _RSASAS(ph)HQADIK_ | |
| LBR | Ubiquitylation | K107 | 0.757 | -0.107 | _SASASHQADIK(gl)EARR_ |
| LBR | Ubiquitylation | K123 | -0.631 | _LTPLILK(gl)PFGNSISR_ | |
| LBR | Phosphorylation | S128 | -0.301 | 0.481 | _LTPLILKPFGNS(ph)ISR_ |
| LBR | Phosphorylation | S130 | -0.662 | 0.294 | _LTPLILKPFGNS(ph)ISR_ |
| LBR | Ubiquitylation | K176 | -0.492 | _REEVK(gl)LK_ | |
| LBR | Ubiquitylation | K178 | -0.282 | 0.282 | _LK(gl)EIDSK_ |
| LBR | Ubiquitylation | K183 | -0.639 | 0.960 | _LKEIDSK(gl)EEK_ |
| LBR | Ubiquitylation | K186 | -0.551 | 0.084 | _EIDSKEEK(gl)YVAK_ |
| LBR | Ubiquitylation | K190 | -0.968 | 0.657 | _YVAK(gl)ELAVR_ |
| LBR | Phosphorylation | S357 | -0.097 | _NDLS(ph)PASSGNAVYDFFIGR_ | |
| LBR | Ubiquitylation | K508 | 0.463 | _GANSQK(gl)NAFR_ | |
| LBR | Ubiquitylation | K524 | -1.353 | _LAHLK(gl)TIHTSTGK_ | |
| LBR | Ubiquitylation | K601 | -0.777 | 0.355 | _YGVAWEK(gl)YCQR_ |
| LSS | Ubiquitylation | K15 | -1.837 | -2.018 | _GGPYK(gl)TEPATDLGR_ |
| LSS | Ubiquitylation | K65 | -1.467 | -1.119 | _NYFK(gl)DLPK_ |
| LSS | Ubiquitylation | K432 | -1.819 | -1.131 | _LSQVPDNPPDYQK(gl)YYR_ |
| LSS | Ubiquitylation | K506 | -1.598 | -1.214 | _NPDGGFATYETK(gl)R_ |
| MSMO1 | Ubiquitylation | K284 | 0.053 | 0.702 | _IFGTDSQYNAYNEK(gl)R_ |
| MVD | Phosphorylation | S96 | 0.160 | 0.254 | _RNS(ph)RDGDPLPSSLSCK_ |
| SQLE | Ubiquitylation | K90 | -2.393 | -1.358 | _SPPESENK(gl)EQLEAR_ |
| SQLE | Ubiquitylation | K157 | -0.878 | _DLK(gl)EPDR_ | |
| SQLE | Ubiquitylation | K235 | -0.829 | _K(gl)AAMAEPNAK_ | |
| SQLE | Ubiquitylation | K400 | -1.368 | _SMPASFLPPSSVKK(gl)_ | |
| SQLE | Ubiquitylation | K556 | -0.794 | _ALLSSGAVLYK(gl)_ | |
| TM7SF2 | Ubiquitylation | K397 | 0.664 | _QCLQK(gl)YGLAWQEYCR_ |
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© Copyright Svejstrup Laboratory 2015