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Query: ABCG1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ABCG1 0 0.971 -0.770 2.080

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ABCG1 Ubiquitylation K446 -1.109 _GK(gl)VCNLVPYLR_

Background Information for ABCG1:


Pubmed-ABCG1 »
Uniprot-ABCG1 »
Biogrid-ABCG1 »
ProteomicsDB-ABCG1 »

Tumorportal-ABCG1 »
COSMIC-ABCG1 »
GenomeRNAi-ABCG1 »
Genecards-ABCG1


Protein-protein Interactions for ABCG1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACSL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait AP1S2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015


Protein Domains in ABCG1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members AAA+_ATPase IPR003593 0.38
Category members ABC_transporter-like IPR003439 0.15
Category members Ribosome_biogen_GTPase_RsgA IPR004881 0.05
Category members ABC_2_trans IPR013525 0


Protein complexes (CORUM database) featuring ABCG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ABCG1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016887 ATPase activity Database 2.28
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0017111 nucleoside-triphosphatase activity Database 0.5
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0055037 recycling endosome Database 0.29
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members Pathway Pathway_756 KEGG_ABC_TRANSPORTERS 0 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0042987 amyloid precursor protein catabolic process Database 0.09
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members GO Category GO:0015485 cholesterol binding Database 0.04
Category members GO Category GO:0010888 negative regulation of lipid storage Database 0.04
Category members GO Category GO:0034436 glycoprotein transport Database 0.04
Category members GO Category GO:0010887 negative regulation of cholesterol storage Database 0.01
Category members GO Category GO:0009897 external side of plasma membrane Database 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_490 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT 0 0
Category members Pathway Pathway_492 REACTOME_LIPOPROTEIN_METABOLISM 0 0
Category members Pathway Pathway_716 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT 0 0
Category members Pathway Pathway_757 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS 0 0
Category members Pathway Pathway_758 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005543 phospholipid binding Database 0
Category members GO Category GO:0005548 phospholipid transporter activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0010033 response to organic substance Database 0
Category members GO Category GO:0010745 negative regulation of macrophage derived foam cell differentiation Database 0
Category members GO Category GO:0010872 regulation of cholesterol esterification Database 0
Category members GO Category GO:0010875 positive regulation of cholesterol efflux Database 0
Category members GO Category GO:0017127 cholesterol transporter activity Database 0
Category members GO Category GO:0019534 toxin transporter activity Database 0
Category members GO Category GO:0030301 cholesterol transport Database 0
Category members GO Category GO:0032367 intracellular cholesterol transport Database 0
Category members GO Category GO:0033344 cholesterol efflux Database 0
Category members GO Category GO:0033700 phospholipid efflux Database 0
Category members GO Category GO:0033993 response to lipid Database 0
Category members GO Category GO:0034374 low-density lipoprotein particle remodeling Database 0
Category members GO Category GO:0034375 high-density lipoprotein particle remodeling Database 0
Category members GO Category GO:0034437 glycoprotein transporter activity Database 0
Category members GO Category GO:0042157 lipoprotein metabolic process Database 0
Category members GO Category GO:0042632 cholesterol homeostasis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043691 reverse cholesterol transport Database 0
Category members GO Category GO:0045542 positive regulation of cholesterol biosynthetic process Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0
Category members GO Category GO:0055091 phospholipid homeostasis Database 0
Category members GO Category GO:0055099 response to high density lipoprotein particle Database 0


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