bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »
bioLOGIC Category

Results for the Category
cholesterol homeostasis
(GO:0042632)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
LDLRAP1 2 0.870 -0.890
LAMTOR1 1 0.700 -0.850 0.343 0.382
SOAT1 0 -1.260 1.790 0.164 0.147
SCARB1 0 0.990 -0.330
SCARB1 0 0.990 -0.330 -0.012 -0.480
APOB 0 0.130 0.050 -4.359 0.702
SIRT1 0 0.910 -0.910
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
EHD1 0 -0.060 0.300
APOA1 0 0.850 -0.420 -3.959
LDLR 0 0.610 -0.680 -0.328
NCOR1 0 -0.820 1.130 -0.827 -0.215 0.037
NPC1 0 0.620 -0.700 0.275 0.103
ABCG1 0 -0.770 2.080

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ABCG1 Ubiquitylation K446 -1.109 _GK(gl)VCNLVPYLR_
CAV1 Ubiquitylation K5 0.591 0.963 _(ac)SGGK(gl)YVDSEGHLYTVPIR_
CAV1 Phosphorylation S6 0.836 0.688 _(ac)ADELS(ph)EKQVYDAHTK_
CAV1 Ubiquitylation K8 0.244 0.734 _(ac)ADELSEK(gl)QVYDAHTK_
CAV1 Ubiquitylation K26 0.724 0.894 _EQGNIYK(gl)PNNK_
CAV1 Ubiquitylation K30 -0.008 0.317 _EQGNIYKPNNK(gl)AMADELSEK_
CAV1 Ubiquitylation K39 0.690 1.170 _AMADELSEK(gl)QVYDAHTK_
CAV1 Phosphorylation S76 0.607 0.527 _AMADELS(ph)EK_
CAV1 Ubiquitylation K176 -0.259 _INLQK(gl)EI_
EHD1 Ubiquitylation K475 -0.521 -0.192 _SK(gl)LPNTVLGK_
LAMTOR1 Ubiquitylation K20 -0.365 -0.474 _K(gl)LLLDPSSPPTK_
LAMTOR1 Phosphorylation S27 -0.440 -0.557 _KLLLDPSS(ph)PPTK_
LAMTOR1 Ubiquitylation K31 -1.467 _KLLLDPSSPPTK(gl)ALNGAEPNYHSLPSAR_
LDLRAP1 Ubiquitylation K5 6.085 8.895 _(ac)MDALK(gl)SAGR_
LDLRAP1 Phosphorylation S14 -0.662 0.149 _ALIRS(ph)PSLAK_
NCOR1 Phosphorylation S1195 -0.029 0.716 _MPIEDS(ph)SPEKGREEAASK_
NCOR1 Phosphorylation S1196 0.087 0.141 _MPIEDSS(ph)PEKGR_
NCOR1 Phosphorylation S1472 0.700 0.536 _AQLS(ph)PGIYDDTSAR_
NCOR1 Phosphorylation S1977 -0.959 -0.974 _YETPSDAIEVIS(ph)PASSPAPPQEK_
NCOR1 Ubiquitylation K1998 -2.086 _LQTYQPEVVK(gl)ANQAENDPTR_
NCOR1 Phosphorylation S2120 0.148 0.154 _VS(ph)PENLVDK_
NCOR1 Phosphorylation S2151 -1.006 -0.922 _SHVSSEPYEPIS(ph)PPQVPVVHEK_
NCOR1 Phosphorylation S2184 0.120 0.226 _S(ph)PGSISYLPSFFTK_
NCOR1 Phosphorylation S2187 0.396 _SPGS(ph)ISYLPSFFTK_
NPC1 Ubiquitylation K1191 0.981 _AFTVSMK(gl)GSR_
SCARB1 Ubiquitylation K480 0.325 0.520 _GSVLQEAK(gl)L_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SOAT1 Ubiquitylation K120 -0.184 _APPEQGK(gl)IFIAR_
SOAT1 Ubiquitylation K353 0.140 _NIK(gl)QEPFSAR_


© Copyright Svejstrup Laboratory 2015