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Query: EHD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EHD1 0 -0.413 -0.060 0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EHD1 Ubiquitylation K475 -0.521 -0.192 _SK(gl)LPNTVLGK_

Background Information for EHD1:


Pubmed-EHD1 »
Uniprot-EHD1 »
Biogrid-EHD1 »
ProteomicsDB-EHD1 »

Tumorportal-EHD1 »
COSMIC-EHD1 »
GenomeRNAi-EHD1 »
Genecards-EHD1


Protein-protein Interactions for EHD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAPD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf54 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFYVE20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EHD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GTP_binding_domain IPR006073 0.59
Category members Dynamin_GTPase IPR001401 0.36
Category members EPS15_homology IPR000261 0
Category members EF_hand_dom IPR002048 0


Protein complexes (CORUM database) featuring EHD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EHD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0005769 early endosome Database 1.26
Category members Pathway Pathway_666 KEGG_ENDOCYTOSIS 0 1.25
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0031095 platelet dense tubular network membrane Database 0.45
Category members GO Category GO:0016197 endosomal transport Database 0.43
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0005768 endosome Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0034383 low-density lipoprotein particle clearance Database 0.07
Category members GO Category GO:0010886 positive regulation of cholesterol storage Database 0.05
Category members GO Category GO:0005811 lipid particle Database 0
Category members GO Category GO:0010008 endosome membrane Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0
Category members GO Category GO:0030139 endocytic vesicle Database 0
Category members GO Category GO:0032456 endocytic recycling Database 0
Category members GO Category GO:0042632 cholesterol homeostasis Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0
Category members GO Category GO:0055038 recycling endosome membrane Database 0


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