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Query: SOAT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SOAT1 0 2.241 -1.260 1.790 0.164 0.147

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SOAT1 Ubiquitylation K353 0.140 _NIK(gl)QEPFSAR_
SOAT1 Ubiquitylation K120 -0.184 _APPEQGK(gl)IFIAR_

Background Information for SOAT1:


Pubmed-SOAT1 »
Uniprot-SOAT1 »
Biogrid-SOAT1 »
ProteomicsDB-SOAT1 »

Tumorportal-SOAT1 »
COSMIC-SOAT1 »
GenomeRNAi-SOAT1 »
Genecards-SOAT1


Protein-protein Interactions for SOAT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM82A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GOLT1B Cat. description Hein, Mann, Cell 2015
Category members IP bait KATNA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCDHB15 Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB11A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB7A Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait SPAST Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM63B Cat. description Hein, Mann, Cell 2015
Category members IP bait VAPA Cat. description Hein, Mann, Cell 2015
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ASGR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM187B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM189A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTH1R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN4R Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SEMA7A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM128 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPAN5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPK1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VNN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YIPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SOAT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members MBOAT_fam IPR004299 0


Protein complexes (CORUM database) featuring SOAT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SOAT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members GO Category GO:0042986 positive regulation of amyloid precursor protein biosynthetic process Database 0.05
Category members GO Category GO:0015485 cholesterol binding Database 0.04
Category members Pathway Pathway_162 KEGG_STEROID_BIOSYNTHESIS 0 0
Category members Pathway Pathway_166 ST_JAK_STAT_PATHWAY 0 0
Category members GO Category GO:0000062 fatty-acyl-CoA binding Database 0
Category members GO Category GO:0010742 macrophage derived foam cell differentiation Database 0
Category members GO Category GO:0033344 cholesterol efflux Database 0
Category members GO Category GO:0034379 very-low-density lipoprotein particle assembly Database 0
Category members GO Category GO:0034435 cholesterol esterification Database 0
Category members GO Category GO:0042632 cholesterol homeostasis Database 0


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