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Query: SCARB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCARB1 0 0.354 0.990 -0.330
SCARB1 0 0.354 0.990 -0.330 -0.012 -0.480

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCARB1 Ubiquitylation K480 0.325 0.520 _GSVLQEAK(gl)L_

Background Information for SCARB1:


Pubmed-SCARB1 »
Uniprot-SCARB1 »
Biogrid-SCARB1 »
ProteomicsDB-SCARB1 »

Tumorportal-SCARB1 »
COSMIC-SCARB1 »
GenomeRNAi-SCARB1 »
Genecards-SCARB1


Protein-protein Interactions for SCARB1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BTNL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BTNL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLDN7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-DRA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCEH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDZK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PON2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPRK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCGB1D4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SFTPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM30B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCARB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CD36 IPR002159 0.21
Category members CD36_antigen IPR005428 0.21


Protein complexes (CORUM database) featuring SCARB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SCARB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005765 lysosomal membrane Database 0.82
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0051856 adhesion to symbiont Database 0.21
Category members GO Category GO:0009986 cell surface Database 0.17
Category members GO Category GO:0030666 endocytic vesicle membrane Database 0.08
Category members GO Category GO:0034383 low-density lipoprotein particle clearance Database 0.07
Category members GO Category GO:0015920 lipopolysaccharide transport Database 0.05
Category members GO Category GO:0010886 positive regulation of cholesterol storage Database 0.05
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_490 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT 0 0
Category members Pathway Pathway_492 REACTOME_LIPOPROTEIN_METABOLISM 0 0
Category members Pathway Pathway_716 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT 0 0
Category members GO Category GO:0001530 lipopolysaccharide binding Database 0
Category members GO Category GO:0001786 phosphatidylserine binding Database 0
Category members GO Category GO:0001875 lipopolysaccharide receptor activity Database 0
Category members GO Category GO:0001935 endothelial cell proliferation Database 0
Category members GO Category GO:0005215 transporter activity Database 0
Category members GO Category GO:0005545 1-phosphatidylinositol binding Database 0
Category members GO Category GO:0005901 caveola Database 0
Category members GO Category GO:0006702 androgen biosynthetic process Database 0
Category members GO Category GO:0006707 cholesterol catabolic process Database 0
Category members GO Category GO:0006869 lipid transport Database 0
Category members GO Category GO:0006910 phagocytosis, recognition Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0008035 high-density lipoprotein particle binding Database 0
Category members GO Category GO:0010595 positive regulation of endothelial cell migration Database 0
Category members GO Category GO:0010867 positive regulation of triglyceride biosynthetic process Database 0
Category members GO Category GO:0010899 regulation of phosphatidylcholine catabolic process Database 0
Category members GO Category GO:0015914 phospholipid transport Database 0
Category members GO Category GO:0030169 low-density lipoprotein particle binding Database 0
Category members GO Category GO:0030301 cholesterol transport Database 0
Category members GO Category GO:0031528 microvillus membrane Database 0
Category members GO Category GO:0031663 lipopolysaccharide-mediated signaling pathway Database 0
Category members GO Category GO:0032497 detection of lipopolysaccharide Database 0
Category members GO Category GO:0033344 cholesterol efflux Database 0
Category members GO Category GO:0034185 apolipoprotein binding Database 0
Category members GO Category GO:0034186 apolipoprotein A-I binding Database 0
Category members GO Category GO:0034375 high-density lipoprotein particle remodeling Database 0
Category members GO Category GO:0034384 high-density lipoprotein particle clearance Database 0
Category members GO Category GO:0042060 wound healing Database 0
Category members GO Category GO:0042157 lipoprotein metabolic process Database 0
Category members GO Category GO:0042632 cholesterol homeostasis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043534 blood vessel endothelial cell migration Database 0
Category members GO Category GO:0043654 recognition of apoptotic cell Database 0
Category members GO Category GO:0043691 reverse cholesterol transport Database 0
Category members GO Category GO:0050764 regulation of phagocytosis Database 0
Category members GO Category GO:0051000 positive regulation of nitric-oxide synthase activity Database 0
Category members GO Category GO:0070328 triglyceride homeostasis Database 0
Category members GO Category GO:0070508 cholesterol import Database 0


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