Results for the Category
positive regulation of cholesterol efflux
(GO:0010875)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| SIRT1 | 0 | 0.910 | -0.910 | |||||
| LRP1 | 0 | -0.360 | 0.400 | 1.199 | 1.016 | |||
| ABCG1 | 0 | -0.770 | 2.080 | |||||
| PTCH1 | 0 | 0.630 | -0.690 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ABCG1 | Ubiquitylation | K446 | -1.109 | _GK(gl)VCNLVPYLR_ | |
| LRP1 | Ubiquitylation | K4527 | -0.315 | _HSLASTDEK(gl)R_ | |
| PTCH1 | Ubiquitylation | K904 | -0.390 | _DKPIDISQLTK(gl)QR_ | |
| SIRT1 | Phosphorylation | S14 | -0.369 | -0.246 | _(ac)ADEAALALQPGGS(ph)PSAAGADR_ |
| SIRT1 | Phosphorylation | S16 | -0.306 | -1.665 | _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_ |
| SIRT1 | Phosphorylation | S26 | -1.047 | -0.245 | _EAAS(ph)SPAGEPLR_ |
| SIRT1 | Phosphorylation | S27 | 0.351 | -0.363 | _EAASS(ph)PAGEPLR_ |
| SIRT1 | Phosphorylation | S47 | -0.574 | -0.607 | _S(ph)PGEPGGAAPER_ |
| SIRT1 | Ubiquitylation | K238 | -1.641 | _RK(gl)DINTIEDAVK_ | |
| SIRT1 | Ubiquitylation | K499 | -2.138 | -0.204 | _LGGEYAK(gl)LCCNPVK_ |
| SIRT1 | Ubiquitylation | K578 | -2.782 | _GCMEEK(gl)PQEVQTSR_ | |
| SIRT1 | Ubiquitylation | K601 | -3.051 | _NVESIAEQMENPDLK(gl)NVGSSTGEK_ |
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