Results for the Category
amyloid precursor protein catabolic process
(GO:0042987)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PSEN2 | 1 | -1.820 | 3.280 | |||||
| PSEN1 | 0 | 0.930 | -1.110 | |||||
| DHCR24 | 0 | 1.100 | -0.830 | 0.024 | -0.083 | |||
| ABCG1 | 0 | -0.770 | 2.080 | |||||
| NCSTN | 0 | -1.540 | 2.100 | 0.618 | 0.379 | |||
| PSENEN | 0 | -0.550 | 0.740 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ABCG1 | Ubiquitylation | K446 | -1.109 | _GK(gl)VCNLVPYLR_ | |
| DHCR24 | Ubiquitylation | K76 | -0.970 | 0.315 | _VRDIQK(gl)QVR_ |
| DHCR24 | Ubiquitylation | K254 | -0.170 | _GLEAICAK(gl)FTHESQR_ | |
| DHCR24 | Ubiquitylation | K313 | 0.393 | _HVENYLK(gl)TNR_ | |
| DHCR24 | Ubiquitylation | K367 | -0.346 | -0.263 | _ISLLK(gl)LTQGETLR_ |
| DHCR24 | Ubiquitylation | K459 | -0.920 | -0.275 | _QLEK(gl)FVR_ |
| DHCR24 | Ubiquitylation | K496 | -0.539 | -0.460 | _EK(gl)LGCQDAFPEVYDK_ |
| DHCR24 | Ubiquitylation | K509 | -0.754 | _LGCQDAFPEVYDK(gl)ICK_ | |
| NCSTN | Ubiquitylation | K110 | 1.107 | _DLMEK(gl)LK_ | |
| PSEN1 | Phosphorylation | S313 | 0.844 | _VSKNS(ph)KYNAESTER_ | |
| PSEN1 | Ubiquitylation | K314 | 0.016 | 0.414 | _NSK(gl)YNAESTER_ |
| PSEN1 | Phosphorylation | S366 | -0.340 | 0.055 | _AAVQELSS(ph)SILAGEDPEER_ |
| PSEN1 | Phosphorylation | S367 | 0.005 | 0.066 | _AAVQELSSS(ph)ILAGEDPEER_ |
| PSEN2 | Phosphorylation | S58 | -0.112 | -0.130 | _TSLM(ox)SAES(ph)PTPR_ |
| PSENEN | Ubiquitylation | K11 | 0.476 | _VSNEEK(gl)LNLCR_ |
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