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BIOCARTA_PPARA_PATHWAY
(Pathway_150)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HSP90AA1 3 -0.150 0.150 0.395 1.024 -1.280 0.611 0.460
HSP90AA1 3 0.170 -0.420 0.395 1.024 -1.280 0.611 0.460
JUN 3 -0.930 0.930 -0.126
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
MED1 1 0.780 -0.520 -1.530 -0.219
HSD17B4 1 0.150 -0.410 0.662 1.589 0.132 0.014
MRPL11 1 -1.750 2.510 0.584 -0.400 -0.422 0.788 0.743
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
NCOR2 1 1.850 -1.050
NCOR2 1 1.850 -1.050 0.037 -1.127
PDGFA 1 0.190 -0.340 -2.109 1.885
PRKAR2B 0 -0.290 0.380
CREBBP 0 0.840 -0.950 -3.889 -1.071
ME1 0
FAT1 0 -0.370 0.210
NCOA1 0 1.240 -0.460
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
MAPK3 0
EHHADH 0 0.390 -0.560 0.812 0.511
PRKAR2A 0 -0.530 1.080 0.026 -1.317 -0.866 0.783 0.007
PRKAR2A 0 -0.530 1.080
APOA1 0 0.850 -0.420 -3.959
DUSP1 0 0.290 -0.100
PIK3CA 0
DUT 0 -0.440 1.310
DUT 0 -0.440 1.310
DUT 0 -0.440 1.310
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
RB1 0 1.180 -1.070 0.429 0.755
RB1 0 1.180 -1.070
NCOR1 0 -0.820 1.130 -0.827 -0.215 0.037
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
PIK3R1 0 1.910 -1.220 -0.441 0.147
PRKCA 0 0.750 -0.690 0.349 0.585
PRKCA 0 0.750 -0.690
ACOX1 0 0.460 -0.300
PRKCB 0 0.260 -0.530
PRKCB 0 0.260 -0.530 0.349 0.585
RELA 0 -1.130 1.600 0.793
STAT5B 0 0.670 -0.960
NR2F1 0 -0.300 -0.080 0.225 0.992 0.424 0.474
SP1 0 0.404 0.333 0.650
SRA1 0

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ACOX1 Phosphorylation S26 -0.372 _DSASFNPELLTHILDGS(ph)PEK_
ACOX1 Ubiquitylation K122 -0.820 _EK(gl)WLLSSK_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
DUSP1 Ubiquitylation K97 -0.523 _SAALDGAK(gl)R_
DUT Phosphorylation S4 0.191 0.429 _PCS(ph)EETPAIS(ph)PSK_
DUT Phosphorylation S11 -0.548 -0.435 _PCSEETPAIS(ph)PSK_
DUT Phosphorylation S13 -0.394 _PCSEETPAISPS(ph)KR_
DUT Ubiquitylation K14 -0.852 -1.290 _PCSEETPAISPSK(gl)R_
DUT Phosphorylation S16 -0.212 _(ac)AAGGAAPETPAISPS(ph)K_
DUT Phosphorylation S88 -0.883 -0.900 _AGGS(ph)PAPGPETPAISPSK_
DUT Phosphorylation S99 -3.045 _AGGSPAPGPETPAIS(ph)PSK_
DUT Phosphorylation S101 -1.411 _AGGSPAPGPETPAISPS(ph)K_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
FAT1 Ubiquitylation K313 -0.225 _SFPGSK(gl)EYK_
FAT1 Ubiquitylation K1542 -1.093 _DQDVPVK(gl)R_
FAT1 Ubiquitylation K4351 -1.682 -1.804 _KPLEEK(gl)PSQPYSAR_
HSD17B4 Ubiquitylation K68 -0.723 _GGK(gl)AVANYDSVEEGEK_
HSP90AA1 Ubiquitylation K69 0.820 -0.090 _YESLTDPSK(gl)LDSGK_
HSP90AA1 Ubiquitylation K74 0.543 _LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1 Ubiquitylation K112 1.304 1.601 _ADLINNLGTIAK(gl)SGTK_
HSP90AA1 Ubiquitylation K185 0.963 _GTK(gl)VILHLK_
HSP90AA1 Ubiquitylation K208 1.745 _IKEIVK(gl)K_
HSP90AA1 Phosphorylation S231 2.338 0.649 _DKEVS(ph)DDEAEEK_
HSP90AA1 Phosphorylation S263 0.095 0.173 _ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1 Ubiquitylation K281 1.267 _IK(gl)EKYIDQEELNK_
HSP90AA1 Ubiquitylation K283 1.442 1.226 _EK(gl)YIDQEELNK_
HSP90AA1 Ubiquitylation K292 -0.237 0.506 _YIDQEELNK(gl)TKPIWTR_
HSP90AA1 Ubiquitylation K294 0.315 8.646 _TK(gl)PIWTR_
HSP90AA1 Ubiquitylation K362 0.969 0.946 _NNIK(gl)LYVR_
HSP90AA1 Ubiquitylation K407 0.827 1.121 _EMLQQSK(gl)ILK_
HSP90AA1 Ubiquitylation K443 0.820 0.951 _FYEQFSK(gl)NIK_
HSP90AA1 Ubiquitylation K446 0.314 1.126 _NIK(gl)LGIHEDSQNR_
HSP90AA1 Ubiquitylation K478 0.799 1.624 _YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1 Ubiquitylation K539 0.353 1.775 _EFEGK(gl)TLVSVTK_
HSP90AA1 Ubiquitylation K559 -0.316 _EGLELPEDEEEKK(gl)K_
HSP90AA1 Ubiquitylation K565 0.903 _K(gl)TKFENLCK_
HSP90AA1 Ubiquitylation K567 0.710 _TK(gl)FENLCK_
HSP90AA1 Ubiquitylation K576 0.874 _IMK(gl)DILEK_
HSP90AA1 Ubiquitylation K581 0.540 0.738 _DILEK(gl)KVEK_
HSP90AA1 Ubiquitylation K582 0.063 0.470 _K(gl)VEKVVVSNR_
HSP90AA1 Ubiquitylation K615 0.715 0.751 _IMK(gl)AQALR_
HSP90AA1 Ubiquitylation K631 0.361 0.974 _DNSTMGYMAAK(gl)K_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
ME1 Ubiquitylation K422 -0.582 _AECSAEQCYK(gl)ITK_
ME1 Ubiquitylation K512 0.582 -0.154 _DVSLK(gl)IAEK_
ME1 Ubiquitylation K516 0.190 _IAEK(gl)IVK_
ME1 Ubiquitylation K536 -1.965 _TATVYPEPQNK(gl)EAFVR_
MED1 Phosphorylation S664 3.368 _DNPAQDFSTLYGSS(ph)PLER_
MED1 Phosphorylation S771 -1.422 _LSS(ph)SDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLR_
MED1 Phosphorylation T1051 -1.201 -1.247 _SQT(ph)PPGVATPPIPK_
MED1 Phosphorylation T1057 -1.294 _SQT(ph)PPGVAT(ph)PPIPK_
MED1 Phosphorylation S1155 0.689 _NSSQSGGKPGS(ph)SPITK_
MED1 Phosphorylation S1156 0.829 1.055 _NSSQSGGKPGSS(ph)PITK_
MED1 Phosphorylation S1192 -0.792 _PSSLM(ox)NPSLSKPNIS(ph)PSHSRPPGGSDK_
MED1 Phosphorylation S1223 1.061 1.013 _AKS(ph)PISSGSGGSHM(ox)SGTSSSSGM(ox)K_
MED1 Phosphorylation S1433 -0.191 _NYGS(ph)PLISGSTPK_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NCOA1 Phosphorylation S22 0.503 0.810 _KGS(ph)PCDTLASSTEK_
NCOR1 Phosphorylation S1195 -0.029 0.716 _MPIEDS(ph)SPEKGREEAASK_
NCOR1 Phosphorylation S1196 0.087 0.141 _MPIEDSS(ph)PEKGR_
NCOR1 Phosphorylation S1472 0.700 0.536 _AQLS(ph)PGIYDDTSAR_
NCOR1 Phosphorylation S1977 -0.959 -0.974 _YETPSDAIEVIS(ph)PASSPAPPQEK_
NCOR1 Ubiquitylation K1998 -2.086 _LQTYQPEVVK(gl)ANQAENDPTR_
NCOR1 Phosphorylation S2120 0.148 0.154 _VS(ph)PENLVDK_
NCOR1 Phosphorylation S2151 -1.006 -0.922 _SHVSSEPYEPIS(ph)PPQVPVVHEK_
NCOR1 Phosphorylation S2184 0.120 0.226 _S(ph)PGSISYLPSFFTK_
NCOR1 Phosphorylation S2187 0.396 _SPGS(ph)ISYLPSFFTK_
NCOR2 Phosphorylation S939 -0.637 _LLS(ph)PRPSLLTPTGDPR_
NCOR2 Phosphorylation S943 -0.740 _LLSPRPS(ph)LLTPTGDPR_
NCOR2 Phosphorylation S956 -0.223 -0.308 _ANAS(ph)PQKPLDLK_
NCOR2 Phosphorylation S1023 -0.334 _S(ph)RSPAPPADKEAFAAEAQK_
NCOR2 Phosphorylation S1025 1.950 _SRS(ph)PAPPADKEAFAAEAQK_
NCOR2 Phosphorylation T1383 -1.746 -2.157 _EGT(ph)PPPPPPSR_
NCOR2 Phosphorylation S1479 0.325 -0.132 _SLIGS(ph)PGR_
NCOR2 Phosphorylation S1778 -0.687 _HSSSPLS(ph)PGGPTHLTKPTTTSSSER_
NCOR2 Phosphorylation S1970 -0.321 _SGLEPAS(ph)SPSK_
NCOR2 Phosphorylation S1971 -0.480 _SGLEPASS(ph)PSK_
NCOR2 Phosphorylation S2223 -0.074 -1.140 _TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR_
NCOR2 Phosphorylation S2258 -0.573 -0.210 _S(ph)PGNTSQPPAFFSK_
NCOR2 Phosphorylation S2413 0.973 _AKS(ph)PAPGLASGDRPPSVSSVHSEGDCNR_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR2A Phosphorylation S99 0.020 0.056 _RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A Phosphorylation T104 -0.175 _RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKAR2B Phosphorylation T69 -0.367 _TWGDLGAAAGGGT(ph)PSK_
PRKAR2B Phosphorylation S114 0.366 0.525 _RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKCA Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCA Ubiquitylation K316 -0.522 -0.535 _LGPAGNK(gl)VISPSEDR_
PRKCB Phosphorylation S10 -0.650 0.036 _(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB Phosphorylation S13 -1.038 0.335 _(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB Phosphorylation S226 0.693 0.415 _STLNPQWNES(ph)FTFK_
PRKCB Ubiquitylation K315 0.213 0.518 _ISQGTK(gl)VPEEK_
RB1 Phosphorylation S69 -3.602 -3.397 _TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1 Ubiquitylation K97 -0.546 _LK(gl)IPDHVR_
RB1 Phosphorylation T388 0.005 0.116 _TLQTDSIDSFETQRT(ph)PR_
RB1 Phosphorylation T405 -0.851 -0.901 _KSNLDEEVNVIPPHT(ph)PVR_
RB1 Phosphorylation S820 -0.019 _S(ph)PYKFPSSPLR_
RB1 Ubiquitylation K823 -2.214 _SPYK(gl)FPSSPLR_
RB1 Phosphorylation S827 0.824 0.111 _FPSS(ph)PLR_
RB1 Phosphorylation S839 -0.701 -1.045 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K842 -0.751 _IPGGNIYISPLK(gl)SPYK_
RB1 Phosphorylation S843 -0.701 -0.022 _IPGGNIYIS(ph)PLKS(ph)PYK_
RB1 Ubiquitylation K846 -2.084 _SPYK(gl)ISEGLPTPTK_
RB1 Phosphorylation T853 0.039 -0.555 _ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1 Ubiquitylation K856 -1.350 _ISEGLPTPTK(gl)MTPR_
RB1 Phosphorylation T858 -0.782 0.564 _ISEGLPT(ph)PTKMT(ph)PR_
RB1 Ubiquitylation K879 -0.187 _FQK(gl)INQMVCNSDR_
SP1 Phosphorylation S2 0.834 1.114 _(ac)S(ph)DQDHSMDEMTAVVK_
SP1 Phosphorylation S7 0.586 0.217 _(ac)SDQDHS(ph)MDEMTAVVK_
SP1 Phosphorylation S56 -0.154 _SSSTGSSSSTGGGGQES(ph)QPSPLALLAATCSR_
SP1 Phosphorylation S59 -0.217 -0.135 _SSSTGSSSSTGGGGQESQPS(ph)PLALLAATCSR_
SRA1 Phosphorylation S69 -4.785 _VPASETS(ph)PGPPPMGPPPPSSK_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_


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