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Query: ACOX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACOX1 0 -1.192 0.460 -0.300

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACOX1 Ubiquitylation K122 -0.820 _EK(gl)WLLSSK_
ACOX1 Phosphorylation S26 -0.372 _DSASFNPELLTHILDGS(ph)PEK_

Background Information for ACOX1:


Pubmed-ACOX1 »
Uniprot-ACOX1 »
Biogrid-ACOX1 »
ProteomicsDB-ACOX1 »

Tumorportal-ACOX1 »
COSMIC-ACOX1 »
GenomeRNAi-ACOX1 »
Genecards-ACOX1


Protein-protein Interactions for ACOX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ACBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ADAMTSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BOC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM60A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRNPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HRSP12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KHDRBS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LACRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LITAF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MBNL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB30 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB6B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RECK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ACOX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Acyl-CoA_oxidase_C IPR002655 0
Category members Acyl-CoA_Oxase/DH_cen-dom IPR006091 0
Category members AcylCo_DH/oxidase_C IPR009075 0
Category members AcylCoA_DH/oxidase_NM_dom IPR009100 0
Category members Acyl-CoA_oxidase IPR012258 0


Protein complexes (CORUM database) featuring ACOX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ACOX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_90 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION 0 0.88
Category members GO Category GO:0016559 peroxisome fission Database 0.54
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members GO Category GO:0016401 palmitoyl-CoA oxidase activity Database 0.26
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase Database 0.23
Category members GO Category GO:0005782 peroxisomal matrix Database 0.23
Category members Pathway Pathway_144 KEGG_BIOSYNTHESIS_OF_UNSATURATED_FATTY_ACIDS 0 0.13
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members Pathway Pathway_143 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM 0 0.07
Category members GO Category GO:0033559 unsaturated fatty acid metabolic process Database 0.07
Category members GO Category GO:0036109 alpha-linolenic acid metabolic process Database 0.07
Category members GO Category GO:0006693 prostaglandin metabolic process Database 0.06
Category members Pathway Pathway_26 REACTOME_PEROXISOMAL_LIPID_METABOLISM 0 0.04
Category members Pathway Pathway_150 BIOCARTA_PPARA_PATHWAY 0 0.04
Category members Pathway Pathway_151 KEGG_ALPHA_LINOLENIC_ACID_METABOLISM 0 0.03
Category members GO Category GO:0005778 peroxisomal membrane Database 0.01
Category members Pathway Pathway_25 KEGG_PEROXISOME 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000038 very long-chain fatty acid metabolic process Database 0
Category members GO Category GO:0003995 acyl-CoA dehydrogenase activity Database 0
Category members GO Category GO:0003997 acyl-CoA oxidase activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0005504 fatty acid binding Database 0
Category members GO Category GO:0005777 peroxisome Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0006631 fatty acid metabolic process Database 0
Category members GO Category GO:0006635 fatty acid beta-oxidation Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Database 0
Category members GO Category GO:0019395 fatty acid oxidation Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0055088 lipid homeostasis Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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