bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: NCOR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NCOR2 1 1.185 1.850 -1.050
NCOR2 1 1.185 1.850 -1.050 0.037 -1.127

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NCOR2 Phosphorylation S1025 1.950 _SRS(ph)PAPPADKEAFAAEAQK_
NCOR2 Phosphorylation S2413 0.973 _AKS(ph)PAPGLASGDRPPSVSSVHSEGDCNR_
NCOR2 Phosphorylation S1479 0.325 -0.132 _SLIGS(ph)PGR_
NCOR2 Phosphorylation S2258 -0.573 -0.210 _S(ph)PGNTSQPPAFFSK_
NCOR2 Phosphorylation S956 -0.223 -0.308 _ANAS(ph)PQKPLDLK_
NCOR2 Phosphorylation S1023 -0.334 _S(ph)RSPAPPADKEAFAAEAQK_
NCOR2 Phosphorylation S1778 -0.687 _HSSSPLS(ph)PGGPTHLTKPTTTSSSER_
NCOR2 Phosphorylation S943 -0.740 _LLSPRPS(ph)LLTPTGDPR_
NCOR2 Phosphorylation S2223 -0.074 -1.140 _TSVLGGGEDGIEPVS(ph)PPEGMTEPGHSR_
NCOR2 Phosphorylation T1383 -1.746 -2.157 _EGT(ph)PPPPPPSR_
NCOR2 Phosphorylation S939 -0.637 _LLS(ph)PRPSLLTPTGDPR_
NCOR2 Phosphorylation S1970 -0.321 _SGLEPAS(ph)SPSK_
NCOR2 Phosphorylation S1971 -0.480 _SGLEPASS(ph)PSK_

Background Information for NCOR2:


Pubmed-NCOR2 »
Uniprot-NCOR2 »
Biogrid-NCOR2 »
ProteomicsDB-NCOR2 »

Tumorportal-NCOR2 »
COSMIC-NCOR2 »
GenomeRNAi-NCOR2 »
Genecards-NCOR2


Protein-protein Interactions for NCOR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXO22 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCAPG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RGMA Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBL1Y Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NCOR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SANT/Myb IPR001005 2.18
Category members Myb-like_dom IPR017877 0.63
Category members Homeodomain-like IPR009057 0


Protein complexes (CORUM database) featuring NCOR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3167 NCOR-SIN3-HDAC-HESX1 complex Database 0.94
Category members Corum 3263 HERP1/HEY2-NCOR-SIN3A complex Database 0.68
Category members Corum 3156 CBF1-HDAC1-SMRT complex Database 0.52
Category members Corum 747 NCOR-SIN3-HDAC1 complex Database 0.52
Category members Corum 745 NCOR-SIN3-RPD3 complex Database 0.47
Category members Corum 1505 NCOR2 complex Database 0.15
Category members Corum 2911 SMRT-SKIP-CBF1 complex Database 0.01
Category members Corum 1188 SMRT core complex Database 0
Category members Corum 58 SMRT complex Database 0
Category members Corum 752 SMRT core complex Database 0


Categories featuring NCOR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0047485 protein N-terminus binding Database 1.84
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members GO Category GO:0016922 ligand-dependent nuclear receptor binding Database 0.89
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_117 REACTOME_SIGNALING_BY_NOTCH 0 0.33
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0017053 transcriptional repressor complex Database 0.28
Category members GO Category GO:0001012 RNA polymerase II regulatory region DNA binding Database 0.27
Category members GO Category GO:0006367 transcription initiation from RNA polymerase II promoter Database 0.25
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members Pathway Pathway_1 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM 0 0.23
Category members GO Category GO:0060206 estrous cycle phase Database 0.23
Category members Pathway Pathway_789 REACTOME_SIGNALING_BY_NOTCH1 0 0.22
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_802 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 0 0.17
Category members GO Category GO:0042826 histone deacetylase binding Database 0.16
Category members GO Category GO:0005112 Notch binding Database 0.14
Category members Pathway Pathway_824 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 0 0.14
Category members GO Category GO:0045599 negative regulation of fat cell differentiation Database 0.13
Category members Pathway Pathway_947 BIOCARTA_EGFR_SMRTE_PATHWAY 0 0.09
Category members Pathway Pathway_822 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 0 0.09
Category members Pathway Pathway_381 BIOCARTA_RARRXR_PATHWAY 0 0.08
Category members Pathway Pathway_823 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY 0 0.07
Category members GO Category GO:0007219 Notch signaling pathway Database 0.05
Category members Pathway Pathway_150 BIOCARTA_PPARA_PATHWAY 0 0.04
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0010243 response to organonitrogen compound Database 0.02
Category members GO Category GO:0042974 retinoic acid receptor binding Database 0.02
Category members Pathway Pathway_1097 BIOCARTA_ETS_PATHWAY 0 0
Category members Pathway Pathway_119 PID_HES_HEY_PATHWAY 0 0
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members Pathway Pathway_755 PID_RXR_VDR_PATHWAY 0 0
Category members Pathway Pathway_892 KEGG_NOTCH_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_946 PID_RETINOIC_ACID_PATHWAY 0 0
Category members GO Category GO:0000118 histone deacetylase complex Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0007595 lactation Database 0
Category members GO Category GO:0021537 telencephalon development Database 0
Category members GO Category GO:0021846 cell proliferation in forebrain Database 0
Category members GO Category GO:0030900 forebrain development Database 0
Category members GO Category GO:0032355 response to estradiol Database 0
Category members GO Category GO:0035259 glucocorticoid receptor binding Database 0
Category members GO Category GO:0042698 ovulation cycle Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0046965 retinoid X receptor binding Database 0
Category members GO Category GO:0050872 white fat cell differentiation Database 0
Category members GO Category GO:0060509 Type I pneumocyte differentiation Database 0


.

© Copyright Svejstrup Laboratory 2015