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Query: SRA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRA1 0 -2.067

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRA1 Phosphorylation S87 -1.025 -1.042 _S(ph)PPVGSGPASGVEPTSFPVESEAR_
SRA1 Phosphorylation S69 -4.785 _VPASETS(ph)PGPPPMGPPPPSSK_

Background Information for SRA1:





Protein-protein Interactions for SRA1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ERCC6L Cat. description Hein, Mann, Cell 2015
Category members IP bait MIB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MLKL Cat. description Hein, Mann, Cell 2015
Category members IP bait OAZ1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait RUFY1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SAP30 Cat. description Hein, Mann, Cell 2015
Category members IP bait TIGD6 Cat. description Hein, Mann, Cell 2015


Protein Domains in SRA1

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SRA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1042 SRA-SRC-1 ribonucleoprotein complex Database 0


Categories featuring SRA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0031252 cell leading edge Database 2.52
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members Pathway Pathway_150 BIOCARTA_PPARA_PATHWAY 0 0.04
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0


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