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PID_CD40_PATHWAY
(Pathway_986)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
JUN 3 -0.930 0.930 -0.126
MAPK14 2 -0.160 -0.350
MAPK9 1 0.110 -0.490
TRAF2 1 -0.570 0.540
TRAF2 1 -0.570 0.540
MAP2K4 0 -0.300 0.320
MAP3K1 0 0.750 -1.270
NFKB1 0 0.720 -0.810
BIRC2 0 -0.730 0.440
BIRC2 0 -0.730 0.440
TDP2 0 0.200 -0.360
TNFAIP3 0 0.760 -0.500
TRAF3 0 -1.050 1.040
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
BCL2L1 0
RELA 0 -1.130 1.600 0.793

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
BCL2L1 Ubiquitylation K87 0.026 _EVIPMAAVK(gl)QALR_
BIRC2 Ubiquitylation K15 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K17 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K38 -0.069 _SIMEDSTILSDWTNSNKQK(gl)_
BIRC2 Ubiquitylation K102 -1.755 _LGDSPIQK(gl)HK_
BIRC2 Ubiquitylation K233 -0.511 _LSNWEPK(gl)DDAMSEHR_
BIRC2 Ubiquitylation K410 0.878 _DLVK(gl)QTVQSK_
BIRC2 Ubiquitylation K490 0.305 0.534 _ANVINK(gl)QEHDIIK_
BIRC2 Ubiquitylation K497 -1.934 _ANVINKQEHDIIK(gl)QK_
JUN Phosphorylation S58 -0.167 -1.247 _AKNS(ph)DLLTSPDVGLLK_
JUN Phosphorylation T62 2.545 1.674 _NSDLLT(ph)SPDVGLLK_
JUN Phosphorylation S63 2.030 1.458 _NSDLLTS(ph)PDVGLLK_
JUN Ubiquitylation K70 9.213 _NSDLLTSPDVGLLK(gl)_
JUN Phosphorylation S73 1.499 0.845 _LAS(ph)PELER_
JUN Phosphorylation S243 -0.642 -1.399 _LQALKEEPQTVPEMPGETPPLS(ph)PIDMESQER_
JUN Ubiquitylation K309 1.034 0.155 _EQVAQLK(gl)QK_
MAP2K4 Phosphorylation S80 0.441 _LRTHS(ph)IESSGK_
MAP3K1 Phosphorylation S292 0.209 _RAPS(ph)PDGFSPYSPEETNR_
MAP3K1 Phosphorylation S506 1.427 _SHDFYSHELS(ph)SPVDSPSSLR_
MAP3K1 Phosphorylation S507 1.436 _SHDFYSHELSS(ph)PVDSPSSLR_
MAP3K1 Phosphorylation S923 0.127 -0.120 _LSAS(ph)SEDISER_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
TDP2 Ubiquitylation K23 -0.309 -0.581 _EAAEEEGEPEVK(gl)K_
TDP2 Ubiquitylation K24 -0.914 -0.896 _EAAEEEGEPEVKK(gl)_
TDP2 Ubiquitylation K82 -1.178 -1.657 _RPETISEPK(gl)TYVDLTNEETTDSTTSK_
TDP2 Ubiquitylation K192 -0.116 -1.471 _LK(gl)SQEIIPFPSTK_
TDP2 Ubiquitylation K203 -0.460 -0.913 _SQEIIPFPSTK(gl)MMR_
TDP2 Ubiquitylation K341 -0.167 _SLDLLGLEK(gl)LDCGR_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
TRAF2 Phosphorylation T7 -0.822 -1.190 _(ac)AAASVT(ph)PPGSLELLQPGFSK_
TRAF2 Ubiquitylation K27 -0.253 2.194 _TLLGTK(gl)LEAK_
TRAF2 Ubiquitylation K119 0.519 _GTLK(gl)EYESCHEGR_
TRAF2 Ubiquitylation K176 -1.233 1.022 _APCCGADVK(gl)AHHEVCPK_
TRAF2 Ubiquitylation K207 0.147 0.918 _FQDHVK(gl)TCGK_
TRAF2 Ubiquitylation K481 -0.507 0.417 _MEAK(gl)NSYVR_
TRAF3 Ubiquitylation K369 -1.061 -2.137 _VTELESVDK(gl)SAGQVAR_


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