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KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PATHWAY
(Pathway_1053)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HSP90AA1 3 -0.150 0.150 0.395 1.024 -1.280 0.611 0.460
HSP90AA1 3 0.170 -0.420 0.395 1.024 -1.280 0.611 0.460
MAPK14 2 -0.160 -0.350
TAB3 2 -0.550 1.560 0.022 -0.207
TAB3 2 -0.550 1.560
HSP90B1 2 0.100 0.120 0.724 1.982 -1.206 0.484 0.477
MAPK9 1 0.110 -0.490
CASP8 1 1.120 -1.090
HSP90AB1 1 1.280 -1.050 0.283 0.786 -1.175 0.317 0.463
TAB1 1 1.890 -0.670
TAB1 1 1.890 -0.670 1.657
RIPK2 1 -1.740 3.580
SUGT1 1 2.450 -0.880 -1.684 0.384
SUGT1 1 2.450 -0.880 -0.106
TAB2 0 -0.030 -0.580
NLRP1 0 -0.960 0.730
XIAP 0 0.600 -0.210
XIAP 0 0.600 -0.210 -1.128
MAPK3 0
IKBKB 0 0.400 0.610
NFKB1 0 0.720 -0.810
BIRC2 0 -0.730 0.440
BIRC2 0 -0.730 0.440
ERBB2IP 0 0.430 0.290 -0.247 -0.786 -0.105
TNFAIP3 0 0.760 -0.500
MAP3K7 0 -1.120 1.140 -1.048
RELA 0 -1.130 1.600 0.793
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BIRC2 Ubiquitylation K15 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K17 -0.259 0.307 _(ac)MEDSTILSDWTNSNK(gl)QK_
BIRC2 Ubiquitylation K38 -0.069 _SIMEDSTILSDWTNSNKQK(gl)_
BIRC2 Ubiquitylation K102 -1.755 _LGDSPIQK(gl)HK_
BIRC2 Ubiquitylation K233 -0.511 _LSNWEPK(gl)DDAMSEHR_
BIRC2 Ubiquitylation K410 0.878 _DLVK(gl)QTVQSK_
BIRC2 Ubiquitylation K490 0.305 0.534 _ANVINK(gl)QEHDIIK_
BIRC2 Ubiquitylation K497 -1.934 _ANVINKQEHDIIK(gl)QK_
CASP8 Ubiquitylation K183 1.917 _IINDYEEFSK(gl)ER_
CASP8 Ubiquitylation K461 -2.031 _NMGK(gl)QMPQPTFTLR_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
ERBB2IP Phosphorylation S1133 -0.960 _TYS(ph)IDGPNASRPQSARPSINEIPER_
HSP90AA1 Ubiquitylation K69 0.820 -0.090 _YESLTDPSK(gl)LDSGK_
HSP90AA1 Ubiquitylation K74 0.543 _LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1 Ubiquitylation K112 1.304 1.601 _ADLINNLGTIAK(gl)SGTK_
HSP90AA1 Ubiquitylation K185 0.963 _GTK(gl)VILHLK_
HSP90AA1 Ubiquitylation K208 1.745 _IKEIVK(gl)K_
HSP90AA1 Phosphorylation S231 2.338 0.649 _DKEVS(ph)DDEAEEK_
HSP90AA1 Phosphorylation S263 0.095 0.173 _ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1 Ubiquitylation K281 1.267 _IK(gl)EKYIDQEELNK_
HSP90AA1 Ubiquitylation K283 1.442 1.226 _EK(gl)YIDQEELNK_
HSP90AA1 Ubiquitylation K292 -0.237 0.506 _YIDQEELNK(gl)TKPIWTR_
HSP90AA1 Ubiquitylation K294 0.315 8.646 _TK(gl)PIWTR_
HSP90AA1 Ubiquitylation K362 0.969 0.946 _NNIK(gl)LYVR_
HSP90AA1 Ubiquitylation K407 0.827 1.121 _EMLQQSK(gl)ILK_
HSP90AA1 Ubiquitylation K443 0.820 0.951 _FYEQFSK(gl)NIK_
HSP90AA1 Ubiquitylation K446 0.314 1.126 _NIK(gl)LGIHEDSQNR_
HSP90AA1 Ubiquitylation K478 0.799 1.624 _YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1 Ubiquitylation K539 0.353 1.775 _EFEGK(gl)TLVSVTK_
HSP90AA1 Ubiquitylation K559 -0.316 _EGLELPEDEEEKK(gl)K_
HSP90AA1 Ubiquitylation K565 0.903 _K(gl)TKFENLCK_
HSP90AA1 Ubiquitylation K567 0.710 _TK(gl)FENLCK_
HSP90AA1 Ubiquitylation K576 0.874 _IMK(gl)DILEK_
HSP90AA1 Ubiquitylation K581 0.540 0.738 _DILEK(gl)KVEK_
HSP90AA1 Ubiquitylation K582 0.063 0.470 _K(gl)VEKVVVSNR_
HSP90AA1 Ubiquitylation K615 0.715 0.751 _IMK(gl)AQALR_
HSP90AA1 Ubiquitylation K631 0.361 0.974 _DNSTMGYMAAK(gl)K_
HSP90AB1 Ubiquitylation K64 0.829 -0.090 _YESLTDPSK(gl)LDSGKELK_
HSP90AB1 Ubiquitylation K69 0.661 0.380 _LDSGK(gl)ELK_
HSP90AB1 Ubiquitylation K72 -1.242 -0.130 _ELK(gl)IDIIPNPQER_
HSP90AB1 Phosphorylation S226 0.404 0.704 _EKEIS(ph)DDEAEEEK_
HSP90AB1 Phosphorylation S255 0.525 0.628 _IEDVGS(ph)DEEDDSGKDKK_
HSP90AB1 Phosphorylation S261 0.520 0.624 _IEDVGSDEEDDS(ph)GKDK_
HSP90AB1 Ubiquitylation K347 0.110 _RAPFDLFENK(gl)K_
HSP90AB1 Ubiquitylation K348 -0.096 _RAPFDLFENKK(gl)_
HSP90AB1 Ubiquitylation K428 0.308 _K(gl)FYEAFSK_
HSP90AB1 Ubiquitylation K435 0.847 0.933 _FYEAFSK(gl)NLK_
HSP90AB1 Ubiquitylation K438 1.021 -0.058 _NLK(gl)LGIHEDSTNR_
HSP90AB1 Ubiquitylation K481 0.811 _MKETQK(gl)SIYYITGESK_
HSP90AB1 Ubiquitylation K491 0.982 1.512 _SIYYITGESK(gl)EQVANSAFVER_
HSP90AB1 Ubiquitylation K531 0.745 1.350 _EFDGK(gl)SLVSVTK_
HSP90AB1 Ubiquitylation K559 0.847 1.549 _AK(gl)FENLCK_
HSP90AB1 Ubiquitylation K565 -0.066 _FENLCK(gl)LMK_
HSP90AB1 Ubiquitylation K573 0.243 0.360 _EILDK(gl)KVEK_
HSP90AB1 Ubiquitylation K574 0.241 0.550 _EILDKK(gl)VEK_
HSP90AB1 Ubiquitylation K623 0.520 1.081 _DNSTMGYM(ox)MAK(gl)K_
HSP90B1 Ubiquitylation K95 0.097 1.380 _LIINSLYK(gl)NK_
HSP90B1 Ubiquitylation K97 -0.155 1.541 _NK(gl)EIFLR_
HSP90B1 Ubiquitylation K161 0.157 0.544 _EELVK(gl)NLGTIAK_
HSP90B1 Ubiquitylation K168 1.363 _NLGTIAK(gl)SGTSEFLNK_
HSP90B1 Phosphorylation S306 -0.709 0.213 _TETVEEPMEEEEAAKEEKEES(ph)DDEAAVEEEEEEK_
HSP90B1 Ubiquitylation K404 -0.189 1.394 _GLFDEYGSK(gl)K_
HSP90B1 Ubiquitylation K405 -0.189 1.394 _GLFDEYGSK(gl)K_
HSP90B1 Ubiquitylation K455 0.816 0.384 _ETLQQHK(gl)LLK_
HSP90B1 Ubiquitylation K593 -0.763 0.376 _FQNVAK(gl)EGVK_
HSP90B1 Ubiquitylation K663 -0.272 _IMK(gl)AQAYQTGK_
HSP90B1 Ubiquitylation K671 -0.264 0.676 _AQAYQTGK(gl)DISTNYYASQK_
HSP90B1 Ubiquitylation K682 0.380 1.163 _DISTNYYASQK(gl)K_
HSP90B1 Ubiquitylation K683 0.380 1.163 _DISTNYYASQK(gl)K_
IKBKB Ubiquitylation K106 0.253 _K(gl)YLNQFENCCGLR_
IKBKB Phosphorylation S672 0.670 0.244 _GPVSGS(ph)PDSMNASR_
MAP3K7 Phosphorylation S374 0.149 -0.337 _GS(ph)SVESLPPTSEGK_
MAP3K7 Phosphorylation S375 0.171 -0.087 _GSS(ph)VESLPPTSEGK_
MAP3K7 Phosphorylation S389 1.072 1.445 _RMS(ph)ADMSEIEAR_
MAP3K7 Phosphorylation S439 0.246 0.198 _S(ph)IQDLTVTGTEPGQVSSR_
MAP3K7 Ubiquitylation K474 -0.385 -0.242 _MITTSGPTSEK(gl)PTR_
MAP3K7 Ubiquitylation K589 -0.104 _SLSTYYQQCK(gl)K_
MAP3K7 Ubiquitylation K590 -0.551 0.560 _K(gl)QLEVIR_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
NFKB1 Phosphorylation S907 -0.025 0.113 _TTSQAHSLPLS(ph)PASTR_
NLRP1 Ubiquitylation K297 -1.598 _SQDPLVK(gl)R_
RIPK2 Ubiquitylation K410 -2.810 _AAFCDHK(gl)TTPCSSAIINPLSTAGNSER_
RIPK2 Phosphorylation S531 0.884 0.839 _SPS(ph)LNLLQNK_
RIPK2 Ubiquitylation K538 -2.659 _SPSLNLLQNK(gl)SM_
SUGT1 Phosphorylation T265 0.177 0.646 _LEGQGDVPT(ph)PK_
SUGT1 Phosphorylation S281 1.261 -0.437 _NLYPSSS(ph)PYTR_
SUGT1 Ubiquitylation K325 0.936 _LFQQIYSDGSDEVK(gl)R_
SUGT1 Ubiquitylation K349 -0.433 _SFMESGGTVLSTNWSDVGK(gl)R_
TAB1 Phosphorylation S7 -0.170 0.140 _S(ph)LLQSEQQPSWTDDLPLCHLSGVGSASNR_
TAB1 Phosphorylation S16 -0.138 0.069 _SLLQSEQQPS(ph)WTDDLPLCHLSGVGSASNR_
TAB1 Ubiquitylation K186 -1.015 _SYSADGK(gl)GTESHPPEDSWLK_
TAB1 Ubiquitylation K371 0.032 _LSQLGLDAGK(gl)IK_
TAB1 Ubiquitylation K373 -0.007 _LSQLGLDAGKIK(gl)_
TAB2 Phosphorylation S580 -0.075 _S(ph)NSISQIPSLEEMQQLR_
TAB2 Phosphorylation S582 0.331 _SNS(ph)ISQIPSLEEMQQLR_
TAB2 Ubiquitylation K653 -0.519 -0.200 _SIIK(gl)TPK_
TAB3 Phosphorylation S4 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TAB3 Phosphorylation S5 3.009 1.852 _(ac)AQS(ph)SPQLDIQVLHDLR_
TNFAIP3 Ubiquitylation K722 0.496 0.176 _ASCK(gl)NILACR_
XIAP Ubiquitylation K31 -0.312 -0.651 _LK(gl)TFANFPSGSPVSASTLAR_
XIAP Ubiquitylation K208 -0.788 -0.846 _LK(gl)NWEPCDR_
XIAP Ubiquitylation K358 -0.720 0.047 _TTEK(gl)TPSLTR_


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