RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
ITPR3	2	-0.190	-0.500				1.489	1.835
MAPK14	2	-0.160	-0.350
ITPR1	2	-0.040	0.000				1.489	1.835
ITPR1	2	-0.040	0.000				0.768	0.643
GNA11	1	2.030	-1.240	0.953			0.764	0.108
RAF1	1	2.020	-1.230
PHKA2	0	-0.110	0.540
ASAH1	0	-0.300	0.340
PIK3CA	0
ITPR2	0	-1.020	0.610				0.952	0.981
GNAI1	0	-0.580	0.990	0.116			-0.747
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
GNAQ	0	0.140	-0.310				0.052	0.449
BRAF	0
DAG1	0	0.210	-0.400
SRC	0	0.050	0.470	-0.031
CFB	0	-0.380	-0.210

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
ASAH1	Ubiquitylation	K461		0.139	_ESLDVYELDAK(gl)QGR_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CFB	Ubiquitylation	K808	-6.292		_VASYGVK(gl)PR_
DAG1	Ubiquitylation	K793		0.843	_LTLEDQATFIK(gl)K_
DAG1	Ubiquitylation	K794	0.899		_LTLEDQATFIKK(gl)_
DAG1	Ubiquitylation	K881	-0.342		_GSRPK(gl)NMTPYR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
GNA11	Ubiquitylation	K16	0.347		_(ac)TLESMMACCLSDEVK(gl)ESKR_
GNA11	Ubiquitylation	K27	0.292	1.135	_RINAEIEK(gl)QLR_
GNA11	Ubiquitylation	K102	0.502	0.512	_ILYK(gl)YEQNK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAQ	Ubiquitylation	K16	0.245		_TLESIMACCLSEEAK(gl)EAR_
GNAQ	Ubiquitylation	K102	-0.299		_IPYK(gl)YEHNK_
ITPR1	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR1	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR1	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR1	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR1	Phosphorylation	S1598	1.165	0.362	_RDS(ph)VLAASR_
ITPR1	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR1	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR1	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR1	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
ITPR2	Ubiquitylation	K909		-0.247	_LSK(gl)FQDGGNNVMR_
ITPR2	Phosphorylation	S1160	0.443	0.895	_GGEEPIEESNILS(ph)PVQDGTK_
ITPR3	Ubiquitylation	K529	1.377		_EK(gl)GGEGPLVR_
ITPR3	Phosphorylation	S934	0.318	-0.802	_KQS(ph)VFSAPSLSAGASAAEPLDR_
ITPR3	Phosphorylation	S937		-0.026	_KQSVFS(ph)APSLSAGASAAEPLDR_
ITPR3	Ubiquitylation	K1534		-0.220	_TLAMVAK(gl)GR_
ITPR3	Phosphorylation	S1832	0.650	0.560	_VAS(ph)FSIPGSSSR_
ITPR3	Ubiquitylation	K2597		-0.819	_NK(gl)NLDWFPR_
ITPR3	Ubiquitylation	K2628		-0.010	_ILQDK(gl)LNSTMK_
ITPR3	Phosphorylation	S2670	1.132	1.555	_LGFVDVQNCIS(ph)R_
MAPK14	Phosphorylation	S2	3.221	3.623	_(ac)S(ph)QERPTFYR_
MAPK14	Phosphorylation	T180	0.958	1.087	_HTDDEM(ox)T(ph)GYVATR_
MAPK14	Phosphorylation	Y182	1.388	1.374	_HTDDEM(ox)TGY(ph)VATR_
MAPK14	Ubiquitylation	K249	0.073	-1.380	_LVGTPGAELLKK(gl)_
PHKA2	Ubiquitylation	K286		-0.415	_NEIISK(gl)LQGR_
PHKA2	Ubiquitylation	K705	0.064		_DILSVMAK(gl)AK_
PHKA2	Ubiquitylation	K707	0.064		_DILSVMAK(gl)AK_
PHKA2	Phosphorylation	S729		0.325	_S(ph)LNLVDSPQPLLEK_
PHKA2	Phosphorylation	S1015	1.066	0.529	_RFS(ph)ADEQFFSVGQAASSSAHSSK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_