bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Category

Results for the Category
negative regulation of transforming growth factor beta receptor signaling pathway
(GO:0030512)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
RPS27A 4 -1.330 2.560 -0.309 0.131 -0.009
UBC 3 -0.309 0.131 -0.009
UBC 3
UBC 3
UBB 3 -0.309 0.131 -0.009
PPP1CA 3 2.150 -0.860
PPP1CA 3 2.150 -0.860 -0.250 0.634 0.981 -0.108 0.171
UBA52 3 -1.260 2.180 -0.309 0.131 -0.009
UBA52 3 -1.260 2.180
PPP1CC 2 0.390 -0.090
PPP1CC 2 0.390 -0.090 0.568 0.526 0.917 -0.533 0.173
PPP1CB 2 -0.790 1.500
PPP1CB 2 -0.790 1.500 0.568 0.526 0.917 -0.533 0.173
PPP1CB 2 -0.790 1.500 0.439 0.908 1.224 -0.104 0.029
HSPA5 1 -0.670 0.310 -0.181 -0.208 0.339 -0.702 -0.192
UCHL5 1 0.080 0.070
UCHL5 1 0.080 0.070 0.053 -0.539 0.136
SKI 1 -1.870 2.800 -1.139 -0.588
STRAP 0 0.490 0.250 1.147 -0.544 -0.436 -0.383 0.218
NEDD4L 0 -0.050 -0.110
XPO1 0 -0.520 0.800 0.240 1.064 0.205 0.673 0.522
GLG1 0 -0.920 0.880 -0.614 -0.283 0.926 0.784
SIRT1 0 0.910 -0.910
PPM1A 0 -0.680 1.340 0.402
PPM1A 0 -0.680 1.340 -1.556 -0.874
STUB1 0 -1.420 2.320 -0.284 0.442 -0.104
TGFB1 0 -0.550 1.050
TGFBR1 0 -0.260 0.020
TGFB3 0 0.900 -0.540
PIN1 0 -0.060 -0.440 -1.204 -0.594
SNX6 0 0.090 -0.550
USP15 0 1.570 -0.780
USP15 0 1.570 -0.780 0.925 -0.319 -0.221
NKX2-1 0 -0.730 0.480 0.174 0.236
NKX2-1 0 -0.730 0.480 -0.123
TGFB1I1 0 0.130 0.160
PDPK1 0 0.050 -0.440
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
PRDM16 0 -1.320 2.300 -0.189 0.565 -1.171
ZFYVE9 0 -0.930 0.760
SMAD3 0 -1.560 1.800
SMAD3 0 0.270 -0.340
LEMD3 0 -0.990 1.690 0.740 0.250
SMAD2 0
EID2 0 -1.000 1.160
PEG10 0

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
EID2 Phosphorylation S94 -0.850 _AAAAGRES(ph)PAAAAAR_
HSPA5 Ubiquitylation K81 -0.455 _LIGDAAK(gl)NQLTSNPENTVFDAK(gl)R_
HSPA5 Ubiquitylation K96 -0.392 -0.109 _NQLTSNPENTVFDAK(gl)R_
HSPA5 Ubiquitylation K118 0.783 _FLPFK(gl)VVEK_
HSPA5 Ubiquitylation K340 0.743 _STMK(gl)PVQK_
HSPA5 Ubiquitylation K352 -0.469 0.822 _VLEDSDLK(gl)K_
HSPA5 Ubiquitylation K353 -0.469 _VLEDSDLK(gl)K_
HSPA5 Ubiquitylation K447 3.097 _NTVVPTKK(gl)_
HSPA5 Ubiquitylation K523 -0.120 0.631 _NK(gl)ITITNDQNR_
LEMD3 Phosphorylation S144 0.229 _VLLGFSSDES(ph)DVEASPR_
LEMD3 Phosphorylation S261 0.546 0.491 _ENYSDS(ph)EEEDDDDVASSR_
LEMD3 Phosphorylation S402 -0.056 _TNNHIGGGAFSVDS(ph)PR_
LEMD3 Phosphorylation S777 0.664 _RNS(ph)PPNSLTPCLK_
LEMD3 Ubiquitylation K787 0.700 0.308 _NSPPNSLTPCLK(gl)IR_
NEDD4L Ubiquitylation K149 -0.001 0.036 _LK(gl)MAYMPK_
NEDD4L Phosphorylation T302 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S303 0.166 0.120 _T(ph)SPQELSEELSR_
NEDD4L Phosphorylation S448 0.067 -0.137 _SLS(ph)SPTVTLSAPLEGAK_
NEDD4L Phosphorylation S449 -0.460 -0.435 _SLSS(ph)PTVTLSAPLEGAK_
NEDD4L Ubiquitylation K462 -0.635 -0.011 _SLSSPTVTLSAPLEGAK(gl)DSPVRR_
NEDD4L Ubiquitylation K471 -0.787 _AVK(gl)DTLSNPQSPQPSPYNSPKPQHK_
NEDD4L Ubiquitylation K531 0.704 _LK(gl)FPVHMR_
NEDD4L Ubiquitylation K539 -1.106 -1.175 _SK(gl)TSLNPNDLGPLPPGWEER_
NEDD4L Ubiquitylation K639 0.649 0.864 _IMSVK(gl)RPDVLK_
PDPK1 Phosphorylation S241 0.358 0.361 _ANS(ph)FVGTAQYVSPELLTEK_
PDPK1 Ubiquitylation K257 0.571 -0.234 _ANSFVGTAQYVSPELLTEK(gl)SACK_
PEG10 Ubiquitylation K22 -0.861 -0.710 _VMK(gl)QSEENNNLQSQVQK_
PEG10 Ubiquitylation K36 -1.757 _QSEENNNLQSQVQK(gl)LTEENTTLR_
PEG10 Ubiquitylation K136 -0.504 -0.228 _WASAK(gl)LER_
PEG10 Ubiquitylation K567 -1.225 -0.448 _NVK(gl)DGLITPTIAPNGAQVLQVK(gl)R_
PEG10 Ubiquitylation K586 -2.378 -0.968 _NVK(gl)DGLITPTIAPNGAQVLQVK(gl)R_
PIN1 Ubiquitylation K13 -0.216 -0.516 _(ac)ADEEKLPPGWEK(gl)R_
PIN1 Ubiquitylation K117 0.117 _SGEEDFESLASQFSDCSSAK(gl)AR_
PPM1A Ubiquitylation K278 -0.176 _VCNEVVDTCLYK(gl)GSR_
PPP1CA Ubiquitylation K6 0.594 0.414 _(ac)SDSEK(gl)LNLDSIIGR_
PPP1CA Ubiquitylation K50 -0.131 0.478 _GLCLK(gl)SR_
PPP1CA Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CA Ubiquitylation K156 0.883 1.047 _YNIK(gl)LWK_
PPP1CA Ubiquitylation K247 0.313 _FLHK(gl)HDLDLICR_
PPP1CA Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CB Ubiquitylation K146 0.352 _FNIK(gl)LWK_
PPP1CB Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CB Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CC Ubiquitylation K35 -0.280 -0.504 _GSKPGK(gl)NVQLQENEIR_
PPP1CC Ubiquitylation K50 -0.131 0.478 _GLCLK(gl)SR_
PPP1CC Ubiquitylation K150 0.321 0.619 _IYGFYDECK(gl)RR_
PPP1CC Ubiquitylation K156 0.883 1.047 _YNIK(gl)LWK_
PPP1CC Ubiquitylation K247 0.313 _FLHK(gl)HDLDLICR_
PPP1CC Ubiquitylation K269 2.628 2.591 _AHQVVEDGYEFFAK(gl)R_
PPP1CC Phosphorylation T320 -0.561 _KPNATRPVT(ph)PPR_
PPP1CC Ubiquitylation K328 0.848 0.425 _GMITK(gl)QAK_
PRDM16 Phosphorylation S62 -1.041 -0.744 _EGS(ph)PYKAPIYIPDDIPIPAEFELR_
PRDM16 Phosphorylation S1039 -0.074 0.136 _NFIGNSNHGSQS(ph)PR_
RPS27A Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
RPS27A Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
RPS27A Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
RPS27A Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
RPS27A Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
RPS27A Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
RPS27A Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
RPS27A Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
RPS27A Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
RPS27A Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
RPS27A Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
RPS27A Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SKI Ubiquitylation K294 -0.126 -0.054 _AYILLSQDYTGK(gl)EEQAR_
SKI Ubiquitylation K365 -0.244 -0.390 _TLAGSSNK(gl)SLGCVHPR_
SKI Phosphorylation S431 -0.475 _VVS(ph)SPPCAAAVSR_
SKI Phosphorylation S432 -0.742 -0.438 _VVSS(ph)PPCAAAVSR_
SKI Phosphorylation S480 -1.160 -1.491 _LTVDTPGAPETLAPVAAPEEDKDS(ph)EAEVEVESR_
SMAD2 Phosphorylation T8 -0.896 -0.885 _(ac)SSILPFT(ph)PPVVK_
SMAD2 Ubiquitylation K13 -0.058 _(ac)SSILPFTPPVVK(gl)R_
SMAD3 Ubiquitylation K13 -0.704 _(ac)SSILPFTPPIVK(gl)R_
SNX6 Ubiquitylation K119 0.721 0.619 _LGEGEGSMTK(gl)EEFTK_
SNX6 Ubiquitylation K291 0.222 _VSADEDLK(gl)LSDLLK_
SNX6 Ubiquitylation K307 0.601 _ESQAAK(gl)DLLYR_
STRAP Ubiquitylation K86 0.067 _DATK(gl)AATAAADFTAK_
STRAP Ubiquitylation K161 1.190 _EISGHTSGIKK(gl)_
STRAP Ubiquitylation K169 0.644 _ALWCSEDK(gl)QILSADDK_
STRAP Ubiquitylation K330 -1.279 _CVLPEEDSGELAK(gl)PK_
STUB1 Phosphorylation S19 0.041 0.082 _LGAGGGS(ph)PEKS(ph)PSAQELK_
STUB1 Ubiquitylation K22 0.017 -0.536 _LGAGGGSPEK(gl)SPSAQELK_
STUB1 Phosphorylation S23 0.078 0.165 _LGAGGGS(ph)PEKS(ph)PSAQELK_
STUB1 Ubiquitylation K30 -0.704 -0.765 _SPSAQELK(gl)EQGNR_
STUB1 Ubiquitylation K41 -0.158 _K(gl)YPEAAACYGR_
STUB1 Ubiquitylation K125 0.325 -0.191 _AYSLAK(gl)EQR_
STUB1 Phosphorylation S273 -0.431 -0.250 _S(ph)PLTQEQLIPNLAMK_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFB1I1 Phosphorylation S68 -0.772 -0.697 _S(ph)PKPAAPAAPPFSSSSGVLGTGLCELDR_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TGFBR1 Ubiquitylation K449 -0.991 _VVCEQK(gl)LRPNIPNR_
TGFBR1 Ubiquitylation K502 0.553 0.430 _TLSQLSQQEGIK(gl)M_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
UBA52 Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBA52 Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBA52 Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBA52 Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBA52 Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBA52 Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBA52 Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBA52 Ubiquitylation K93 0.181 2.418 _YNCDK(gl)MICR_
UBA52 Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBA52 Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBA52 Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBA52 Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBA52 Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBB Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBB Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBB Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBB Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBB Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBB Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBB Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBB Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBB Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBB Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBB Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBB Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UBC Ubiquitylation K6 1.066 0.995 _MQIFVK(gl)TLTGK_
UBC Ubiquitylation K11 -0.488 -0.081 _TLTGK(gl)TITLEVEPSDTIENVKAK(gl)_
UBC Ubiquitylation K27 -0.882 -0.159 _TLTGK(gl)TITLEVEPSDTIENVK(gl)AK_
UBC Ubiquitylation K29 -1.087 -1.029 _AK(gl)IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K33 -0.736 -0.407 _IQDK(gl)EGIPPDQQR_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Ubiquitylation K48 -0.062 0.315 _LIFAGK(gl)QLEDGRTLSDYNIQK_
UBC Phosphorylation S57 1.909 0.548 _TLS(ph)DYNIQK_
UBC Ubiquitylation K63 0.276 0.299 _TLSDYNIQK(gl)ESTLHLVLR_
UBC Ubiquitylation K99 0.109 2.111 _VK(gl)LAVLK_
UBC Ubiquitylation K104 0.674 2.102 _LAVLK(gl)YYK_
UBC Ubiquitylation K107 2.949 3.611 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K113 1.572 3.672 _YYK(gl)VDENGK(gl)ISR_
UBC Ubiquitylation K152 4.747 4.970 _CCLTYCFNK(gl)PEDK_
UBC Ubiquitylation K156 4.809 _CCLTYCFNKPEDK(gl)_
UCHL5 Ubiquitylation K154 0.112 0.468 _QQMFEFDTK(gl)TSAK_
UCHL5 Ubiquitylation K210 -0.599 0.531 _RIQK(gl)YSEGEIR_
UCHL5 Ubiquitylation K234 0.086 0.335 _MIYEQK(gl)IAELQR_
UCHL5 Ubiquitylation K277 0.914 _NQMLIEEEVQK(gl)LKR_
UCHL5 Ubiquitylation K279 1.986 0.052 _NQMLIEEEVQKLK(gl)_
UCHL5 Ubiquitylation K315 -0.307 _TLAEHQQLIPLVEK(gl)AK_
UCHL5 Ubiquitylation K317 -0.037 0.724 _TLAEHQQLIPLVEKAK(gl)_
USP15 Phosphorylation S225 -0.837 _GPS(ph)TPKKPLEQSC_
USP15 Phosphorylation T226 -1.049 -0.318 _GPST(ph)PKKPLEQSC_
USP15 Phosphorylation S229 0.423 0.578 _S(ph)PGASNFSTLPK_
XPO1 Phosphorylation S391 -0.074 0.083 _ESPFSTSAS(ph)PLLSGSQHFDVPPR_
XPO1 Ubiquitylation K455 0.519 0.708 _DTDSINLYK(gl)NM(ox)R_
XPO1 Ubiquitylation K531 0.402 _DLLGLCEQK(gl)R_
XPO1 Ubiquitylation K680 -0.376 _NVDILK(gl)DPETVK_
XPO1 Ubiquitylation K693 0.285 0.582 _QLGSILK(gl)TNVR_
XPO1 Ubiquitylation K700 -0.104 _ACK(gl)AVGHPFVIQLGR_
ZFYVE9 Ubiquitylation K543 1.139 _GNEATEGSGLLLNSTGDLMK(gl)K_
ZFYVE9 Ubiquitylation K544 1.139 _GNEATEGSGLLLNSTGDLMK(gl)K_
ZFYVE9 Ubiquitylation K622 0.886 _NKNDILGKAK(gl)_


.

© Copyright Svejstrup Laboratory 2015