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Query: STRAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STRAP 0 1.259 0.490 0.250 1.147 -0.544 -0.436 -0.383 0.218

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
STRAP Ubiquitylation K86 0.067 _DATK(gl)AATAAADFTAK_
STRAP Ubiquitylation K161 1.190 _EISGHTSGIKK(gl)_
STRAP Ubiquitylation K169 0.644 _ALWCSEDK(gl)QILSADDK_
STRAP Ubiquitylation K330 -1.279 _CVLPEEDSGELAK(gl)PK_

Background Information for STRAP:


Pubmed-STRAP »
Uniprot-STRAP »
Biogrid-STRAP »
ProteomicsDB-STRAP »

Tumorportal-STRAP »
COSMIC-STRAP »
GenomeRNAi-STRAP »
Genecards-STRAP


Protein-protein Interactions for STRAP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CSDE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN3 Cat. description Hein, Mann, Cell 2015
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN7 Cat. description Hein, Mann, Cell 2015
Category members IP bait SARS Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRNP70 Cat. description Hein, Mann, Cell 2015
Category members IP bait STRAP Cat. description Hein, Mann, Cell 2015
Category members IP bait DDX20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GEMIN6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GEMIN8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSNAX Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in STRAP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12


Protein complexes (CORUM database) featuring STRAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1751 SMN complex Database 0.37
Category members Corum 1143 SMN complex Database 0.14
Category members Corum 3297 SMN complex (GEMIN6,7, UNRIP), SMN-independent intermediate Database 0


Categories featuring STRAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_777 REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 0 0.89
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members Pathway Pathway_794 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS 0 0.29
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members Pathway Pathway_816 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING 0 0.23
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Database 0.02
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0030054 cell junction Database 0


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