bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: LEMD3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LEMD3 0 4.898 -0.990 1.690 0.740 0.250

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LEMD3 Phosphorylation S777 0.664 _RNS(ph)PPNSLTPCLK_
LEMD3 Phosphorylation S261 0.546 0.491 _ENYSDS(ph)EEEDDDDVASSR_
LEMD3 Ubiquitylation K787 0.700 0.308 _NSPPNSLTPCLK(gl)IR_
LEMD3 Phosphorylation S402 -0.056 _TNNHIGGGAFSVDS(ph)PR_
LEMD3 Phosphorylation S144 0.229 _VLLGFSSDES(ph)DVEASPR_

Background Information for LEMD3:


Pubmed-LEMD3 »
Uniprot-LEMD3 »
Biogrid-LEMD3 »
ProteomicsDB-LEMD3 »

Tumorportal-LEMD3 »
COSMIC-LEMD3 »
GenomeRNAi-LEMD3 »
Genecards-LEMD3


Protein-protein Interactions for LEMD3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait AOC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C13orf16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDHR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1467 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LAMP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LRRC32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MME Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHGB4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMAD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMAD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYT12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRHDE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LEMD3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members LEM_dom IPR003887 0.28
Category members LEM/LEM-like_dom IPR011015 0.28
Category members Inner-Nucl-membr_MAN1 IPR018996 0.04


Protein complexes (CORUM database) featuring LEMD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5615 Emerin complex 52 Database 0.99


Categories featuring LEMD3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005637 nuclear inner membrane Database 1.98
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0005639 integral to nuclear inner membrane Database 0.35
Category members GO Category GO:0051726 regulation of cell cycle Database 0.11
Category members GO Category GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Database 0.02
Category members Disease phenotype 12q14_microdeletion_syndrome 12q14 microdeletion syndrome Database 0
Category members GO Category GO:0030514 negative regulation of BMP signaling pathway Database 0
Category members GO Category GO:0032926 negative regulation of activin receptor signaling pathway Database 0
Category members GO Category GO:0035914 skeletal muscle cell differentiation Database 0


.

© Copyright Svejstrup Laboratory 2015