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Query: USP15

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP15 0 1.705 1.570 -0.780
USP15 0 1.705 1.570 -0.780 0.925 -0.319 -0.221

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP15 Phosphorylation S229 0.423 0.578 _S(ph)PGASNFSTLPK_
USP15 Phosphorylation T226 -1.049 -0.318 _GPST(ph)PKKPLEQSC_
USP15 Phosphorylation S225 -0.837 _GPS(ph)TPKKPLEQSC_

Background Information for USP15:





Protein-protein Interactions for USP15

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATL3 Cat. description Hein, Mann, Cell 2015
Category members IP bait BAG6;BAT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ID1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MKNK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGTB Cat. description Hein, Mann, Cell 2015
Category members IP bait SORT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TCEAL4 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMEM132A Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait OBFC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMB9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RHPN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF19B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SART3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBE2E3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP15

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Pept_C19_DUSP IPR006615 0.23
Category members RNA3'P_cycl/enolpyr_Trfase_a/b IPR013792 0.06


Protein complexes (CORUM database) featuring USP15

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP15

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0035520 monoubiquitinated protein deubiquitination Database 0.54
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0007179 transforming growth factor beta receptor signaling pathway Database 0.25
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Database 0.02
Category members GO Category GO:0005160 transforming growth factor beta receptor binding Database 0
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0046332 SMAD binding Database 0
Category members GO Category GO:0060389 pathway-restricted SMAD protein phosphorylation Database 0


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