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Query: SNX6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNX6 0 1.340 0.090 -0.550

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNX6 Ubiquitylation K119 0.721 0.619 _LGEGEGSMTK(gl)EEFTK_
SNX6 Ubiquitylation K307 0.601 _ESQAAK(gl)DLLYR_
SNX6 Ubiquitylation K291 0.222 _VSADEDLK(gl)LSDLLK_

Background Information for SNX6:





Protein-protein Interactions for SNX6

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C7orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKMT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNM3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB42 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GATS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HENMT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait POTEB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTEX1D2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEAD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TREML2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSPYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VAPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNX6

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phox IPR001683 0.24
Category members Vps5_C IPR015404 0.08
Category members BAR_dom IPR004148 0
Category members SNX5/SNX6/SNX32 IPR014637 0


Protein complexes (CORUM database) featuring SNX6

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1058 SNX complex (SNX1, SNX6) Database 0


Categories featuring SNX6

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006886 intracellular protein transport Database 2.48
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0035091 phosphatidylinositol binding Database 0.62
Category members GO Category GO:0030659 cytoplasmic vesicle membrane Database 0.62
Category members GO Category GO:0031901 early endosome membrane Database 0.58
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0042147 retrograde transport, endosome to Golgi Database 0.26
Category members GO Category GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway Database 0.02
Category members GO Category GO:0007154 cell communication Database 0
Category members GO Category GO:0007175 negative regulation of epidermal growth factor-activated receptor activity Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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