RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
W

Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
SF3B3	2	-2.590	5.210	0.333	-0.136	0.248	-0.316	0.030
SF3B2	1	0.230	0.340	0.157	-0.446	-0.060	-0.624	-0.234
SNRPD2	1	-1.740	2.880	0.068	-0.598	0.211	0.010	0.140
SNRPB2	1	2.000	-1.110	0.093	-0.673	0.119	-0.315
TRAP1	1	2.490	-0.940	1.091	1.105	-1.705	1.051	0.619
SNRPA1	1	-1.610	3.360	-0.071	-0.629	0.211	-0.681	-0.320
RBM17	1	-1.230	1.900	-0.359	-0.577	-0.033	-0.049	0.215
U2AF2	0	-0.290	1.210	0.056	0.174	-0.026
HMG20B	0	-0.570	0.110
CHERP	0	-0.490	1.010	0.253	-0.239	0.275	0.284	0.212
SF3A1	0
SF3A1	0			0.065	-0.677	0.139	-0.601	-0.044
SNRPD3	0			-0.044	-0.427	0.192
PHF5A	0	-0.460	1.210	0.236	-0.190	0.159	-0.003	-0.019
SF3A2	0	-1.400	2.280	0.210	-0.671	0.296	-0.187	0.298
DHX15	0	0.520	0.680	-0.678	0.000	0.359	0.277	0.140
SF3B1	0			0.308	-0.445	-0.096	-0.608	-0.188
SMNDC1	0	0.060	-0.120		-0.870	-0.139	-0.838	-0.317
SNRPB	0	-0.690	0.900	0.279	-0.218	0.342	0.246	0.550
DNAJC8	0	0.620	-0.350	0.219	-0.312	0.403	-1.048	-0.198
SRSF1	0	-1.250	2.260
SRSF1	0	-1.250	2.260	0.403	-0.228	0.177	0.550	0.395
SNRPF	0			-0.086	-0.877	-0.179	-0.438	0.348
SNRPG	0			-0.190	-0.311	0.245	0.156	0.568
SNRPG	0
HSPD1	0	1.020	-0.650	1.151	0.719	-0.757
DDX46	0	0.020	-0.760	0.220	0.222	-0.279	-0.224	-0.110
DDX46	0	0.020	-0.760				0.189	0.029
U2AF1	0	-0.080	-0.050	0.129	-0.015	0.165	0.219	0.101
U2SURP	0	-0.960	0.990	-0.013	-0.374	-0.036	-0.060	0.277
SNRPD1	0	-0.780	0.750	0.034	-0.359	0.355	-1.109	-0.252
SF3B5	0			-0.097	-0.286	0.556	-1.038	-0.371
PUF60	0	0.250	-0.120			0.006	-0.269	0.417
SNRPE	0	-1.140	2.270	-0.259	-0.638	-0.181	0.064	-0.174
SF3A3	0			0.259	-0.407	0.363

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
CHERP	Ubiquitylation	K177	0.538	1.097	_DAISAGK(gl)NWMFSNAK_
CHERP	Ubiquitylation	K901	0.763		_NK(gl)SYSFIAR_
DDX46	Ubiquitylation	K272	0.174		_VVTVVTTKK(gl)_
DDX46	Ubiquitylation	K389	-0.180		_ILNSLKK(gl)_
DDX46	Ubiquitylation	K417	0.205	0.586	_DLIGIAK(gl)TGSGK_
DDX46	Ubiquitylation	K765	-0.308		_AEGK(gl)IIKK_
DDX46	Phosphorylation	S804	0.446	0.367	_AALGLQDS(ph)DDEDAAVDIDEQIESMFNSK_
DDX46	Ubiquitylation	K895	0.021		_GGTILAPTVSAK(gl)TIAEQLAEK_
DDX46	Ubiquitylation	K908	0.147		_INAK(gl)LNYVPLEK_
DDX46	Ubiquitylation	K1026		-0.184	_LQNSYQPTNK(gl)GR_
DHX15	Ubiquitylation	K133	0.923	-0.436	_YYDILKK(gl)_
DHX15	Ubiquitylation	K143	-0.233	-0.100	_LQLPVWEYK(gl)DR_
DHX15	Ubiquitylation	K230	0.506	0.114	_FEDCSSAK(gl)TILK_
DHX15	Ubiquitylation	K480	-0.389		_TRPGK(gl)CFR_
DHX15	Ubiquitylation	K488	0.072	-0.656	_LYTEK(gl)AYK_
DHX15	Ubiquitylation	K491	-0.156	-1.074	_AYK(gl)TEMQDNTYPEILR_
DHX15	Ubiquitylation	K754	-0.102		_TCTDIK(gl)PEWLVK_
DHX15	Ubiquitylation	K786	0.217	-1.242	_IIAK(gl)LQSK_
DHX15	Ubiquitylation	K790	-0.133		_LQSK(gl)EYSQY_
DNAJC8	Ubiquitylation	K40	0.442	0.895	_DSVLTSK(gl)NQIER_
DNAJC8	Ubiquitylation	K135	0.605		_EYVEHTVK(gl)ER_
HMG20B	Phosphorylation	T167	0.485	0.715	_EDS(ph)SSGLMNT(ph)LLNGHK_
HSPD1	Phosphorylation	S70	0.210	0.487	_TVIIEQSWGS(ph)PK_
HSPD1	Ubiquitylation	K82	-0.300		_DGVTVAK(gl)SIDLK_
HSPD1	Ubiquitylation	K87	-0.005	0.292	_SIDLK(gl)DKYK_
HSPD1	Ubiquitylation	K130		-0.428	_EGFEK(gl)ISK_
HSPD1	Ubiquitylation	K233	0.853	0.024	_GYISPYFINTSK(gl)GQK_
HSPD1	Ubiquitylation	K292	0.339		_LK(gl)VGLQVVAVK_
PHF5A	Ubiquitylation	K3	-0.574		_(ac)AK(gl)HHPDLIFCR_
PHF5A	Ubiquitylation	K95	0.907		_IVNLGSSK(gl)TDLFYER_
RBM17	Phosphorylation	S2		1.665	_(ac)S(ph)LYDDLGVETSDSK_
RBM17	Phosphorylation	S155	-0.257	-0.289	_RPDPDS(ph)DEDEDYERER_
RBM17	Phosphorylation	S169		-1.481	_S(ph)MGGAAIAPPTSLVEK_
RBM17	Phosphorylation	S222	0.222	-0.079	_S(ph)PTGPSNSFLANMGGTVAHK_
RBM17	Phosphorylation	T224	0.201		_SPT(ph)GPSNSFLANMGGTVAHK_
SF3A1	Ubiquitylation	K55	0.117		_NIVDK(gl)TASFVAR_
SF3A1	Ubiquitylation	K102	1.185		_VSEFK(gl)EGK_
SF3A1	Ubiquitylation	K188	0.396		_QFLTQLMQK(gl)EQR_
SF3A1	Phosphorylation	S226	0.535	0.611	_FGESEEVEMEVES(ph)DEEDDKQEK_
SF3A1	Ubiquitylation	K251	0.117		_VEWAK(gl)FQER_
SF3A1	Ubiquitylation	K419	-3.113	-1.120	_ASKPLPPAPAPDEYLVSPITGEK(gl)IPASK_
SF3A1	Ubiquitylation	K424	-0.037		_IPASK(gl)MQEHMR_
SF3A1	Ubiquitylation	K754	0.250		_IHEATGMPAGK(gl)QK_
SF3A2	Ubiquitylation	K91	-1.755		_EAK(gl)EAPAQPAPEK_
SF3A2	Ubiquitylation	K103	0.607		_VK(gl)VEVKK_
SF3A2	Ubiquitylation	K107	0.324		_VKVEVK(gl)K_
SF3A3	Ubiquitylation	K153	0.414		_YINLK(gl)ASEK_
SF3A3	Ubiquitylation	K201	-0.229		_VK(gl)PLQDQNELFGK_
SF3A3	Phosphorylation	S295	0.125		_SLES(ph)LDTSLFAK_
SF3A3	Ubiquitylation	K420	-0.387		_GPK(gl)AFQR_
SF3A3	Ubiquitylation	K489	0.581		_WQPDTEEEYEDSSGNVVNK(gl)K_
SF3A3	Ubiquitylation	K490	0.581		_WQPDTEEEYEDSSGNVVNK(gl)K_
SF3A3	Ubiquitylation	K496	0.160	-0.491	_TYEDLK(gl)R_
SF3B1	Phosphorylation	S129	-0.787	-0.713	_TMIIS(ph)PERLDPFADGGK_
SF3B1	Phosphorylation	T142	-0.892	-2.157	_TMIIS(ph)PERLDPFADGGKT(ph)PDPK_
SF3B1	Phosphorylation	T207	-1.127	-1.868	_WDQTADQT(ph)PGAT(ph)PK_
SF3B1	Phosphorylation	T211	-0.765	-1.099	_WDQTADQT(ph)PGAT(ph)PK_
SF3B1	Phosphorylation	T223	-0.989	-1.111	_LSSWDQAET(ph)PGHTPSLR_
SF3B1	Phosphorylation	T227	-1.216	-0.904	_LSSWDQAETPGHT(ph)PSLR_
SF3B1	Phosphorylation	T235		-1.156	_WDET(ph)PGR_
SF3B1	Phosphorylation	T273	-0.351	-0.627	_GDT(ph)PGHATPGHGGATSSAR_
SF3B1	Phosphorylation	T278	-0.033	-0.482	_GDTPGHAT(ph)PGHGGATSSAR_
SF3B1	Phosphorylation	T303		-1.006	_TERDT(ph)PGHGSGWAETPR_
SF3B1	Phosphorylation	S308	-0.512	-0.240	_DTPGHGS(ph)GWAETPRTDR_
SF3B1	Phosphorylation	T313	-0.638	-0.898	_DTPGHGSGWAET(ph)PR_
SF3B1	Phosphorylation	T326	-1.194	-0.893	_GGDSIGET(ph)PT(ph)PGASK_
SF3B1	Phosphorylation	T328	-1.194	-1.428	_GGDSIGET(ph)PT(ph)PGASK_
SF3B1	Ubiquitylation	K333	-1.360		_GGDSIGETPTPGASK(gl)R_
SF3B1	Phosphorylation	S349		-0.947	_SRWDETPASQMGGS(ph)TPVLTPGK_
SF3B1	Phosphorylation	T350	-0.911	-0.979	_SRWDETPASQMGGST(ph)PVLTPGK_
SF3B1	Phosphorylation	T432	-1.068	-1.330	_KLT(ph)ATPTPLGGM(ox)TGFHM(ox)QTEDR_
SF3B1	Phosphorylation	T434	-0.601	-1.311	_LTAT(ph)PTPLGGMTGFHMQTEDR_
SF3B1	Phosphorylation	S488	0.467	-0.012	_LLVDVDESTLS(ph)PEEQKER_
SF3B1	Ubiquitylation	K793	0.904	0.908	_VVK(gl)QCCGTDGVEANYIK_
SF3B1	Ubiquitylation	K963	1.062	0.292	_TAVVMK(gl)TCQEEK_
SF3B1	Ubiquitylation	K1014		-0.389	_MTPPIK(gl)DLLPR_
SF3B1	Ubiquitylation	K1025		0.848	_LTPILK(gl)NR_
SF3B1	Ubiquitylation	K1292		0.731	_IYNDDK(gl)NTYIR_
SF3B2	Ubiquitylation	K280	0.474		_ILQLK(gl)ESR_
SF3B2	Phosphorylation	S289		2.309	_QEEM(ox)NS(ph)QQEEEEMETDAR_
SF3B2	Phosphorylation	S302	0.747	0.772	_S(ph)SLGQSASETEEDTVSVSK_
SF3B2	Phosphorylation	S303	0.747	0.772	_S(ph)SLGQSASETEEDTVSVSK_
SF3B2	Phosphorylation	S307	1.121	1.192	_SSLGQS(ph)ASETEEDTVSVSK_
SF3B2	Phosphorylation	S309	0.696	0.852	_SSLGQSAS(ph)ETEEDTVSVSK_
SF3B2	Ubiquitylation	K394	0.161		_IFEAFK(gl)LTDDVKK_
SF3B2	Ubiquitylation	K492	0.640		_LLVHLK(gl)ATR_
SF3B2	Ubiquitylation	K543	0.559		_EALQEK(gl)EEQK_
SF3B2	Ubiquitylation	K547	0.271		_EALQEKEEQK(gl)TMK_
SF3B2	Ubiquitylation	K563	0.609		_MGK(gl)IDIDYQK_
SF3B2	Phosphorylation	S778	-0.295		_KKIEEAM(ox)DGS(ph)ETPQLFTVLPEK_
SF3B2	Phosphorylation	T780	-0.159	-0.706	_IEEAM(ox)DGSET(ph)PQLFTVLPEK_
SF3B3	Ubiquitylation	K101		1.551	_NM(ox)FEK(gl)IHQETFGK_
SF3B3	Ubiquitylation	K109	0.083	-0.137	_IHQETFGK(gl)SGCRR_
SF3B3	Ubiquitylation	K546		0.526	_TIVK(gl)CAVNQR_
SF3B3	Ubiquitylation	K965		0.907	_VLIGVGK(gl)LLR_
SF3B3	Ubiquitylation	K974	0.479		_VYDLGK(gl)KK_
SF3B3	Ubiquitylation	K975	0.552		_VYDLGKK(gl)_
SF3B3	Ubiquitylation	K1074	-1.824		_LPPNTNDEVDEDPTGNK(gl)ALWDR_
SF3B3	Ubiquitylation	K1206		-1.861	_NVSEELDRTPPEVSK(gl)K_
SF3B3	Ubiquitylation	K1207	-1.934	-1.861	_NVSEELDRTPPEVSKK(gl)_
SMNDC1	Phosphorylation	S201	-0.733	-0.231	_RSIFAS(ph)PESVTGK_
SNRPA1	Ubiquitylation	K67		-1.041	_LK(gl)TLLVNNNR_
SNRPA1	Ubiquitylation	K149	-0.174	-1.201	_VLDFQK(gl)VK_
SNRPA1	Ubiquitylation	K160	0.416		_QEAEK(gl)MFK_
SNRPA1	Ubiquitylation	K172	0.514	0.038	_GAQLAK(gl)DIAR_
SNRPA1	Ubiquitylation	K179	-0.103		_SK(gl)TFNPGAGLPTDKK_
SNRPA1	Phosphorylation	T180		-0.576	_SKT(ph)FNPGAGLPTDKK_
SNRPA1	Ubiquitylation	K191	-0.454		_TFNPGAGLPTDK(gl)K_
SNRPA1	Ubiquitylation	K192	-0.058		_TFNPGAGLPTDKK(gl)_
SNRPA1	Phosphorylation	S197		-0.078	_GGPS(ph)PGDVEAIK_
SNRPA1	Ubiquitylation	K221	0.206	0.311	_LK(gl)GLLQSGQIPGR_
SNRPB	Ubiquitylation	K8	0.805		_SSK(gl)MLQHIDYR_
SNRPB	Ubiquitylation	K32		0.987	_IFIGTFK(gl)_
SNRPB	Ubiquitylation	K88	-0.870		_GENLVSMTVEGPPPK(gl)DTGIAR_
SNRPB2	Ubiquitylation	K85	1.475	0.758	_IQYAK(gl)TDSDIISK_
SNRPB2	Ubiquitylation	K93	1.448	1.158	_TDSDIISK(gl)MR_
SNRPD1	Ubiquitylation	K44	0.032		_AVK(gl)MTLK_
SNRPD2	Phosphorylation	S2	-0.117	0.507	_(ac)S(ph)LLNKPK_
SNRPD2	Ubiquitylation	K6	-0.352		_(ac)SLLNK(gl)PK_
SNRPD2	Ubiquitylation	K8	-0.201	-0.603	_(ac)SLLNKPK(gl)SEMTPEELQK_
SNRPD2	Phosphorylation	T12		0.766	_SEMT(ph)PEELQKR_
SNRPD2	Ubiquitylation	K98	0.883	0.887	_YISK(gl)MFLR_
SNRPD2	Ubiquitylation	K118	-0.918	-0.587	_NPLIAGK(gl)_
SNRPD3	Ubiquitylation	K78		0.797	_FLILPDMLK(gl)NAPMLK_
SNRPD3	Ubiquitylation	K84	-0.440	0.082	_NAPMLK(gl)SMK_
SNRPF	Ubiquitylation	K8	-1.763		_(ac)SLPLNPK(gl)PFLNGLTGKPVMVK_
SNRPF	Ubiquitylation	K17	-1.612		_(ac)SLPLNPKPFLNGLTGK(gl)PVMVK_
SNRPF	Ubiquitylation	K24	0.208	0.915	_LK(gl)WGMEYK_
SNRPG	Ubiquitylation	K3	0.152		_(ac)SK(gl)AHPPELKK(gl)_
SNRPG	Ubiquitylation	K11	-0.955		_AHPPELKK(gl)_
SNRPG	Ubiquitylation	K20	-0.065		_LSLK(gl)LNGGR_
SRSF1	Ubiquitylation	K30	0.295	1.069	_TK(gl)DIEDVFYK_
SRSF1	Ubiquitylation	K38	-0.206		_DIEDVFYK(gl)YGAIR_
SRSF1	Ubiquitylation	K48	0.753		_DIDLK(gl)NRR_
SRSF1	Ubiquitylation	K138	-0.322		_VVVSGLPPSGSWQDLK(gl)DHMR_
SRSF1	Ubiquitylation	K165	0.718		_K(gl)EDMTYAVR_
SRSF1	Ubiquitylation	K174	0.393		_K(gl)LDNTK(gl)FR_
SRSF1	Ubiquitylation	K179	0.296		_K(gl)LDNTK(gl)FR_
SRSF1	Phosphorylation	S199	0.467	0.632	_VDGPRS(ph)PS(ph)YGR_
SRSF1	Phosphorylation	S201	0.651	0.628	_VDGPRS(ph)PS(ph)YGR_
U2AF1	Ubiquitylation	K15	0.020		_DK(gl)VNCSFYFK_
U2AF2	Phosphorylation	S2	0.658	0.706	_(ac)S(ph)DFDEFER_
U2AF2	Ubiquitylation	K70	0.614		_GAK(gl)EEHGGLIR_
U2AF2	Phosphorylation	S79	-0.077	0.135	_GAKEEHGGLIRS(ph)PR_
U2AF2	Ubiquitylation	K462	0.048		_VVVTK(gl)YCDPDSYHR_
U2SURP	Phosphorylation	S67	-0.879	-0.918	_ESLCDS(ph)PHQNLSRPLLENK_
U2SURP	Phosphorylation	S202	0.734	0.603	_S(ph)NLELFKEELK_
U2SURP	Phosphorylation	S485	0.110	0.458	_LYSILQGDS(ph)PTK_
U2SURP	Ubiquitylation	K760	-0.492		_VAPSK(gl)WEAVDESELEAQAVTTSK_