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Query: U2SURP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
U2SURP 0 1.629 -0.960 0.990 -0.013 -0.374 -0.036 -0.060 0.277

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
U2SURP Phosphorylation S202 0.734 0.603 _S(ph)NLELFKEELK_
U2SURP Phosphorylation S485 0.110 0.458 _LYSILQGDS(ph)PTK_
U2SURP Phosphorylation S67 -0.879 -0.918 _ESLCDS(ph)PHQNLSRPLLENK_
U2SURP Ubiquitylation K760 -0.492 _VAPSK(gl)WEAVDESELEAQAVTTSK_

Background Information for U2SURP:





Protein-protein Interactions for U2SURP

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRSR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in U2SURP

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members CID_dom IPR006569 1.43
Category members ENTH_VHS IPR008942 0.96
Category members Surp IPR000061 0
Category members mRNA_splic_Cwf21 IPR013170 0


Protein complexes (CORUM database) featuring U2SURP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2755 17S U2 snRNP Database 1.77


Categories featuring U2SURP

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0006396 RNA processing Database 0.17


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