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Query: SF3B5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SF3B5 0 -1.236 -0.097 -0.286 0.556 -1.038 -0.371

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SF3B5:


Pubmed-SF3B5 »
Uniprot-SF3B5 »
Biogrid-SF3B5 »
ProteomicsDB-SF3B5 »

Tumorportal-SF3B5 »
COSMIC-SF3B5 »
GenomeRNAi-SF3B5 »
Genecards-SF3B5


Protein-protein Interactions for SF3B5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GBAS Cat. description Hein, Mann, Cell 2015
Category members IP bait IWS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SF3B5
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SF3B5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 430 18S U11/U12 snRNP Database 0.29
Category members Corum 1737 SF3b complex Database 0.08


Categories featuring SF3B5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29


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