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Query: DHX15

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHX15 0 1.815 0.520 0.680 -0.678 0.000 0.359 0.277 0.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHX15 Ubiquitylation K230 0.506 0.114 _FEDCSSAK(gl)TILK_
DHX15 Ubiquitylation K143 -0.233 -0.100 _LQLPVWEYK(gl)DR_
DHX15 Ubiquitylation K133 0.923 -0.436 _YYDILKK(gl)_
DHX15 Ubiquitylation K488 0.072 -0.656 _LYTEK(gl)AYK_
DHX15 Ubiquitylation K491 -0.156 -1.074 _AYK(gl)TEMQDNTYPEILR_
DHX15 Ubiquitylation K786 0.217 -1.242 _IIAK(gl)LQSK_
DHX15 Ubiquitylation K480 -0.389 _TRPGK(gl)CFR_
DHX15 Ubiquitylation K754 -0.102 _TCTDIK(gl)PEWLVK_
DHX15 Ubiquitylation K790 -0.133 _LQSK(gl)EYSQY_

Background Information for DHX15:


Pubmed-DHX15 »
Uniprot-DHX15 »
Biogrid-DHX15 »
ProteomicsDB-DHX15 »

Tumorportal-DHX15 »
COSMIC-DHX15 »
GenomeRNAi-DHX15 »
Genecards-DHX15


Protein-protein Interactions for DHX15
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCT8 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFAP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait C16orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZGPAT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHX15
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DUF1605 IPR011709 0.02
Category members Helicase-assoc_dom IPR007502 0


Protein complexes (CORUM database) featuring DHX15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 430 18S U11/U12 snRNP Database 0.29
Category members Corum 1332 Large Drosha complex Database 0.08


Categories featuring DHX15
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0003725 double-stranded RNA binding Database 0.1
Category members GO Category GO:0003724 RNA helicase activity Database 0.07


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