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Query: SF3A2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SF3A2 0 2.833 -1.400 2.280 0.210 -0.671 0.296 -0.187 0.298

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SF3A2 Ubiquitylation K91 -1.755 _EAK(gl)EAPAQPAPEK_
SF3A2 Ubiquitylation K103 0.607 _VK(gl)VEVKK_
SF3A2 Ubiquitylation K107 0.324 _VKVEVK(gl)K_

Background Information for SF3A2:





Protein-protein Interactions for SF3A2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA10 Cat. description Hein, Mann, Cell 2015
Category members IP bait PIGS Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SF3A2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2_matrin IPR000690 0
Category members Znf_U1 IPR003604 0


Protein complexes (CORUM database) featuring SF3A2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 1734 SF3A1-SF3A2-SF3A3 complex Database 0


Categories featuring SF3A2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0030532 small nuclear ribonucleoprotein complex Database 0.15
Category members GO Category GO:0000389 mRNA 3'-splice site recognition Database 0


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