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Query: SF3A3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SF3A3 0 0.837 0.259 -0.407 0.363

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SF3A3 Ubiquitylation K496 0.160 -0.491 _TYEDLK(gl)R_
SF3A3 Ubiquitylation K153 0.414 _YINLK(gl)ASEK_
SF3A3 Ubiquitylation K201 -0.229 _VK(gl)PLQDQNELFGK_
SF3A3 Phosphorylation S295 0.125 _SLES(ph)LDTSLFAK_
SF3A3 Ubiquitylation K420 -0.387 _GPK(gl)AFQR_
SF3A3 Ubiquitylation K489 0.581 _WQPDTEEEYEDSSGNVVNK(gl)K_
SF3A3 Ubiquitylation K490 0.581 _WQPDTEEEYEDSSGNVVNK(gl)K_

Background Information for SF3A3:


Pubmed-SF3A3 »
Uniprot-SF3A3 »
Biogrid-SF3A3 »
ProteomicsDB-SF3A3 »

Tumorportal-SF3A3 »
COSMIC-SF3A3 »
GenomeRNAi-SF3A3 »
Genecards-SF3A3


Protein-protein Interactions for SF3A3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ANXA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BAG4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSPBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SF3A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP47 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRSR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SF3A3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2_matrin IPR000690 0


Protein complexes (CORUM database) featuring SF3A3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 1734 SF3A1-SF3A2-SF3A3 complex Database 0


Categories featuring SF3A3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0000375 RNA splicing, via transesterification reactions Database 0.73
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000389 mRNA 3'-splice site recognition Database 0


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