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Query: PUF60

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PUF60 0 3.292 0.250 -0.120 0.006 -0.269 0.417
PUF60 0 3.292 0.250 -0.120 1.254 0.094 0.254 0.179 0.144

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PUF60 Ubiquitylation K168 0.047 _SIDMSWDSVTMK(gl)HK_
PUF60 Ubiquitylation K253 1.188 _SVFEAFGKIK(gl)_

Background Information for PUF60:


Pubmed-PUF60 »
Uniprot-PUF60 »
Biogrid-PUF60 »
ProteomicsDB-PUF60 »

Tumorportal-PUF60 »
COSMIC-PUF60 »
GenomeRNAi-PUF60 »
Genecards-PUF60


Protein-protein Interactions for PUF60
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APC Cat. description Hein, Mann, Cell 2015
Category members IP bait AXIN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C1QBP Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB2A Cat. description Hein, Mann, Cell 2015
Category members IP bait TECPR2 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2K Cat. description Hein, Mann, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PUF60
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PUF60
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2755 17S U2 snRNP Database 1.77


Categories featuring PUF60
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex Database 0.3
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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