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Query: DNAJC8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DNAJC8 0 0.563 0.620 -0.350 0.219 -0.312 0.403 -1.048 -0.198

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DNAJC8 Ubiquitylation K40 0.442 0.895 _DSVLTSK(gl)NQIER_
DNAJC8 Ubiquitylation K135 0.605 _EYVEHTVK(gl)ER_

Background Information for DNAJC8:


Pubmed-DNAJC8 »
Uniprot-DNAJC8 »
Biogrid-DNAJC8 »
ProteomicsDB-DNAJC8 »

Tumorportal-DNAJC8 »
COSMIC-DNAJC8 »
GenomeRNAi-DNAJC8 »
Genecards-DNAJC8


Protein-protein Interactions for DNAJC8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNTROB Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EGR1 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MMGT1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PIGS Cat. description Hein, Mann, Cell 2015
Category members IP bait PSMB4 Cat. description Hein, Mann, Cell 2015
Category members IP bait REEP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015


Protein Domains in DNAJC8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DnaJ_domain IPR001623 0.3


Protein complexes (CORUM database) featuring DNAJC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2755 17S U2 snRNP Database 1.77


Categories featuring DNAJC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99


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