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Query: DDX46

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX46 0 1.986 0.020 -0.760 0.189 0.029
DDX46 0 1.986 0.020 -0.760 0.220 0.222 -0.279 -0.224 -0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX46 Ubiquitylation K417 0.205 0.586 _DLIGIAK(gl)TGSGK_
DDX46 Phosphorylation S804 0.446 0.367 _AALGLQDS(ph)DDEDAAVDIDEQIESMFNSK_
DDX46 Ubiquitylation K1026 -0.184 _LQNSYQPTNK(gl)GR_
DDX46 Ubiquitylation K272 0.174 _VVTVVTTKK(gl)_
DDX46 Ubiquitylation K389 -0.180 _ILNSLKK(gl)_
DDX46 Ubiquitylation K765 -0.308 _AEGK(gl)IIKK_
DDX46 Ubiquitylation K895 0.021 _GGTILAPTVSAK(gl)TIAEQLAEK_
DDX46 Ubiquitylation K908 0.147 _INAK(gl)LNYVPLEK_

Background Information for DDX46:


Pubmed-DDX46 »
Uniprot-DDX46 »
Biogrid-DDX46 »
ProteomicsDB-DDX46 »

Tumorportal-DDX46 »
COSMIC-DDX46 »
GenomeRNAi-DDX46 »
Genecards-DDX46


Protein-protein Interactions for DDX46
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C10orf125 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HSD3B2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MTUS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX46
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members RNA_helicase_DEAD_Q_motif IPR014014 0.24


Protein complexes (CORUM database) featuring DDX46
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2755 17S U2 snRNP Database 1.77


Categories featuring DDX46
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0015030 Cajal body Database 0.04


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