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Query: SNRPD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNRPD1 0 -0.545 -0.780 0.750 0.034 -0.359 0.355 -1.109 -0.252

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNRPD1 Ubiquitylation K44 0.032 _AVK(gl)MTLK_

Background Information for SNRPD1:


Pubmed-SNRPD1 »
Uniprot-SNRPD1 »
Biogrid-SNRPD1 »
ProteomicsDB-SNRPD1 »

Tumorportal-SNRPD1 »
COSMIC-SNRPD1 »
GenomeRNAi-SNRPD1 »
Genecards-SNRPD1


Protein-protein Interactions for SNRPD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GEMIN5 Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN7 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRNP70 Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2BP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LSM6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNRPD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ribonucl_LSM IPR001163 0
Category members Ribonucl_LSM_euk/arc IPR006649 0
Category members LSM_dom IPR010920 0


Protein complexes (CORUM database) featuring SNRPD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 1183 CDC5L complex Database 2.07
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 5615 Emerin complex 52 Database 0.99
Category members Corum 430 18S U11/U12 snRNP Database 0.29
Category members Corum 1746 SMN containing complex Database 0.19
Category members Corum 1068 12S U11 snRNP Database 0.17
Category members Corum 1143 SMN complex Database 0.14
Category members Corum 833 6S methyltransferase complex Database 0.06
Category members Corum 5613 Emerin complex 25 Database 0.04
Category members Corum 1142 SMN complex Database 0
Category members Corum 1745 SMN complex Database 0
Category members Corum 3118 SMN1-SIP1-SNRP complex Database 0
Category members Corum 819 20S methylosome-SmD complex Database 0
Category members Corum 834 20S methylosome and RG-containing Sm protein complex Database 0
Category members Corum 835 6S methyltransferase and RG-containing Sm proteins complex Database 0


Categories featuring SNRPD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members GO Category GO:0000245 spliceosomal complex assembly Database 0.39
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0030532 small nuclear ribonucleoprotein complex Database 0.15
Category members GO Category GO:0000387 spliceosomal snRNP assembly Database 0.04
Category members GO Category GO:0034660 ncRNA metabolic process Database 0


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