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Query: PHF5A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHF5A 0 2.300 -0.460 1.210 0.236 -0.190 0.159 -0.003 -0.019

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHF5A Ubiquitylation K3 -0.574 _(ac)AK(gl)HHPDLIFCR_
PHF5A Ubiquitylation K95 0.907 _IVNLGSSK(gl)TDLFYER_

Background Information for PHF5A:


Pubmed-PHF5A »
Uniprot-PHF5A »
Biogrid-PHF5A »
ProteomicsDB-PHF5A »

Tumorportal-PHF5A »
COSMIC-PHF5A »
GenomeRNAi-PHF5A »
Genecards-PHF5A


Protein-protein Interactions for PHF5A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHST15 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait LCK Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP3CB Cat. description Hein, Mann, Cell 2015


Protein Domains in PHF5A
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PHF5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 1737 SF3b complex Database 0.08


Categories featuring PHF5A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005686 U2 snRNP Database 0.74
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28


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