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Query: CHERP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CHERP 0 3.656 -0.490 1.010 0.253 -0.239 0.275 0.284 0.212

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CHERP Ubiquitylation K177 0.538 1.097 _DAISAGK(gl)NWMFSNAK_
CHERP Ubiquitylation K901 0.763 _NK(gl)SYSFIAR_

Background Information for CHERP:


Pubmed-CHERP »
Uniprot-CHERP »
Biogrid-CHERP »
ProteomicsDB-CHERP »

Tumorportal-CHERP »
COSMIC-CHERP »
GenomeRNAi-CHERP »
Genecards-CHERP


Protein-protein Interactions for CHERP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CD44 Cat. description Hein, Mann, Cell 2015
Category members IP bait EMC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KIFC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM26 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZMYND8 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGFR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDFY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZRSR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CHERP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RNA_pol_II-bd IPR006903 2.39
Category members ENTH_VHS IPR008942 0.96
Category members G_patch_dom IPR000467 0.09
Category members Surp IPR000061 0


Protein complexes (CORUM database) featuring CHERP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2755 17S U2 snRNP Database 1.77


Categories featuring CHERP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members GO Category GO:0051209 release of sequestered calcium ion into cytosol Database 0.01
Category members GO Category GO:0006874 cellular calcium ion homeostasis Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0033017 sarcoplasmic reticulum membrane Database 0
Category members GO Category GO:0051533 positive regulation of NFAT protein import into nucleus Database 0


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