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Query: SNRPA1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNRPA1 1 3.246 -1.610 3.360 -0.071 -0.629 0.211 -0.681 -0.320

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SNRPA1 Ubiquitylation K221 0.206 0.311 _LK(gl)GLLQSGQIPGR_
SNRPA1 Ubiquitylation K172 0.514 0.038 _GAQLAK(gl)DIAR_
SNRPA1 Phosphorylation S197 -0.078 _GGPS(ph)PGDVEAIK_
SNRPA1 Phosphorylation T180 -0.576 _SKT(ph)FNPGAGLPTDKK_
SNRPA1 Ubiquitylation K67 -1.041 _LK(gl)TLLVNNNR_
SNRPA1 Ubiquitylation K149 -0.174 -1.201 _VLDFQK(gl)VK_
SNRPA1 Ubiquitylation K160 0.416 _QEAEK(gl)MFK_
SNRPA1 Ubiquitylation K179 -0.103 _SK(gl)TFNPGAGLPTDKK_
SNRPA1 Ubiquitylation K191 -0.454 _TFNPGAGLPTDK(gl)K_
SNRPA1 Ubiquitylation K192 -0.058 _TFNPGAGLPTDKK(gl)_

Background Information for SNRPA1:





Protein-protein Interactions for SNRPA1

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait KCNK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNRPA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNRPA1

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members U2A'_phosphoprotein32A_C IPR003603 0.18


Protein complexes (CORUM database) featuring SNRPA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 1183 CDC5L complex Database 2.07
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 1261 SRm160/300 complex Database 0.02


Categories featuring SNRPA1

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0005686 U2 snRNP Database 0.74
Category members GO Category GO:0019013 viral nucleocapsid Database 0.55
Category members GO Category GO:0030532 small nuclear ribonucleoprotein complex Database 0.15


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