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Query: SNRPE

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SNRPE 0 1.901 -1.140 2.270 -0.259 -0.638 -0.181 0.064 -0.174

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SNRPE:


Pubmed-SNRPE »
Uniprot-SNRPE »
Biogrid-SNRPE »
ProteomicsDB-SNRPE »

Tumorportal-SNRPE »
COSMIC-SNRPE »
GenomeRNAi-SNRPE »
Genecards-SNRPE


Protein-protein Interactions for SNRPE
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait EIF3I Cat. description Hein, Mann, Cell 2015
Category members IP bait TBC1D9 Cat. description Hein, Mann, Cell 2015
Category members IP bait LSM6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPG Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SNRPE
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ribonucl_LSM IPR001163 0
Category members Ribonucl_LSM_euk/arc IPR006649 0
Category members LSM_dom IPR010920 0


Protein complexes (CORUM database) featuring SNRPE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 2755 17S U2 snRNP Database 1.77
Category members Corum 430 18S U11/U12 snRNP Database 0.29
Category members Corum 1068 12S U11 snRNP Database 0.17
Category members Corum 1143 SMN complex Database 0.14
Category members Corum 1142 SMN complex Database 0
Category members Corum 1745 SMN complex Database 0
Category members Corum 2757 SMN complex, U7 snRNA specific Database 0
Category members Corum 3118 SMN1-SIP1-SNRP complex Database 0
Category members Corum 835 6S methyltransferase and RG-containing Sm proteins complex Database 0


Categories featuring SNRPE
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0005681 spliceosomal complex Database 3.88
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0000245 spliceosomal complex assembly Database 0.39
Category members GO Category GO:0005689 U12-type spliceosomal complex Database 0.29
Category members GO Category GO:0030532 small nuclear ribonucleoprotein complex Database 0.15
Category members Pathway Pathway_853 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 0 0.05
Category members GO Category GO:0000387 spliceosomal snRNP assembly Database 0.04
Category members Pathway Pathway_885 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS 0 0
Category members Disease phenotype Hypotrichosis_simplex Hypotrichosis simplex Database 0
Category members GO Category GO:0005683 U7 snRNP Database 0
Category members GO Category GO:0008334 histone mRNA metabolic process Database 0
Category members GO Category GO:0034660 ncRNA metabolic process Database 0
Category members GO Category GO:0042633 hair cycle Database 0


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