RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GSK3B	2	1.020	-0.870				-1.128	1.091
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
FOXO3	2	-0.410	-0.120
CTNNA1	1	-0.520	1.660		-0.690	-1.164
CTNNA1	1	-0.520	1.660	0.139			0.436	0.323
PIK3R2	1	2.740	-1.180				0.269	0.348
CCND1	1	-1.820	3.470
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
TCF7L1	1	-2.040	2.970	-0.741
ILK	1	-1.560	3.680				-0.463	-0.527
MAP2K1	1	-1.590	2.780
NRAS	1	1.810	-0.720				0.246	-0.346
BAD	0	-0.660	1.190
CDH1	0	0.150	0.280	-0.623
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
CTNNA2	0	0.660	-0.640	-1.825			0.254	0.247
CTNNA2	0	0.660	-0.640	0.139			0.436	0.323
MLH1	0	-0.460	0.110	-0.360	1.227	1.219
ARAF	0	0.550	-0.670
ARAF	0	0.550	-0.670
TCF7	0	1.040	-0.330	-0.741
MAPK3	0
AKT2	0	-1.420	2.210	-0.194
APC	0	0.810	-0.720				0.008	0.065
APC2	0	0.850	-0.820				0.008	0.065
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
ELK1	0
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
MYC	0	0.170	0.550	-2.443	-0.949	-0.454		-1.290
LEF1	0	-0.710	0.790	-0.741
PDPK1	0	0.050	-0.440
TP53	0	-1.070	1.050	-2.808	0.076	-0.094	0.436	0.497
ERBB2	0	-1.310	1.360
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
TCF7L2	0	-0.550	0.790	-0.741
BRAF	0
CTNNB1	0	0.490	-0.230
CTNNB1	0	0.490	-0.230	-0.415			0.628	0.215
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
CTNNA3	0	-0.010	-0.400	0.139			0.436	0.323

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
APC	Phosphorylation	S746	0.284	0.140	_DANIMS(ph)PGSSLPSLHVR_
APC	Phosphorylation	S749		0.276	_YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC	Phosphorylation	S782	-0.471	-0.446	_ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC	Phosphorylation	S1044	0.097	0.452	_YSDEQLNSGRQS(ph)PSQNER_
APC	Phosphorylation	S1046	0.412	1.084	_YSDEQLNSGRQSPS(ph)QNER_
APC	Phosphorylation	S1362	-0.007	0.328	_AVEFSSGAKS(ph)PSK_
APC	Phosphorylation	T1440	-1.261	-0.875	_SKT(ph)PPPPPQTAQTK_
APC	Phosphorylation	T1775		0.099	_KPT(ph)SPVKPIPQNTEYR_
APC	Phosphorylation	S1776	0.019	0.099	_KPTS(ph)PVKPIPQNTEYR_
APC	Phosphorylation	S2095		0.363	_DIQRPDSEHGLS(ph)PDSENFDWK_
APC	Phosphorylation	S2127		-0.031	_AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC	Phosphorylation	S2260	-0.624		_TPAS(ph)KSPSEGQTATTSPR_
APC	Phosphorylation	S2262	-0.026	0.240	_TPASKS(ph)PSEGQTATTSPR_
APC	Phosphorylation	S2451	-0.249	-0.285	_EAPS(ph)PTLR_
APC	Phosphorylation	S2537		-0.505	_SHSES(ph)PSRLPINR_
APC	Phosphorylation	S2571	0.693	0.817	_TGS(ph)SSSILSASSESSEK_
APC	Phosphorylation	S2673	0.326	0.501	_S(ph)GRSPTGNTPPVIDSVSEK_
APC	Phosphorylation	S2676	-0.478	0.096	_SGRS(ph)PTGNTPPVIDSVSEK_
APC	Phosphorylation	T2678	-0.028	0.136	_SPT(ph)GNTPPVIDSVSEK_
APC2	Phosphorylation	S746	0.284	0.140	_DANIMS(ph)PGSSLPSLHVR_
APC2	Phosphorylation	S749		0.276	_YKDANIM(ox)SPGS(ph)SLPSLHVR_
APC2	Phosphorylation	S782	-0.471	-0.446	_ALEAELDAQHLSETFDNIDNLS(ph)PK_
APC2	Phosphorylation	S1044	0.097	0.452	_YSDEQLNSGRQS(ph)PSQNER_
APC2	Phosphorylation	S1046	0.412	1.084	_YSDEQLNSGRQSPS(ph)QNER_
APC2	Phosphorylation	S1362	-0.007	0.328	_AVEFSSGAKS(ph)PSK_
APC2	Phosphorylation	T1440	-1.261	-0.875	_SKT(ph)PPPPPQTAQTK_
APC2	Phosphorylation	T1775		0.099	_KPT(ph)SPVKPIPQNTEYR_
APC2	Phosphorylation	S1776	0.019	0.099	_KPTS(ph)PVKPIPQNTEYR_
APC2	Phosphorylation	S2095		0.363	_DIQRPDSEHGLS(ph)PDSENFDWK_
APC2	Phosphorylation	S2127		-0.031	_AIQEGANSIVSSLHQAAAAACLS(ph)R_
APC2	Phosphorylation	S2260	-0.624		_TPAS(ph)KSPSEGQTATTSPR_
APC2	Phosphorylation	S2262	-0.026	0.240	_TPASKS(ph)PSEGQTATTSPR_
APC2	Phosphorylation	S2451	-0.249	-0.285	_EAPS(ph)PTLR_
APC2	Phosphorylation	S2537		-0.505	_SHSES(ph)PSRLPINR_
APC2	Phosphorylation	S2571	0.693	0.817	_TGS(ph)SSSILSASSESSEK_
APC2	Phosphorylation	S2673	0.326	0.501	_S(ph)GRSPTGNTPPVIDSVSEK_
APC2	Phosphorylation	S2676	-0.478	0.096	_SGRS(ph)PTGNTPPVIDSVSEK_
APC2	Phosphorylation	T2678	-0.028	0.136	_SPT(ph)GNTPPVIDSVSEK_
ARAF	Phosphorylation	T227		0.017	_STSTPNVHMVSTT(ph)APMDSNLIQLTGQSFSTDAAGSR_
ARAF	Phosphorylation	S260	0.245		_GS(ph)PSPASVSSGR_
ARAF	Ubiquitylation	K543	-1.068	-0.962	_ISSNCPK(gl)AMR_
ARAF	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
BAD	Phosphorylation	S74	-0.904	-0.452	_HS(ph)SYPAGTEDDEGM(ox)GEEPSPFR_
BAD	Phosphorylation	S75	-0.914	-0.660	_HSS(ph)YPAGTEDDEGMGEEPSPFR_
BAD	Phosphorylation	S97		0.056	_S(ph)RSAPPNLWAAQR_
BAD	Phosphorylation	S99	-0.299	0.161	_S(ph)APPNLWAAQR_
BAD	Phosphorylation	S118	1.277	1.089	_RM(ox)S(ph)DEFVDSFKK_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CCND1	Ubiquitylation	K33		-0.490	_AMLK(gl)AEETCAPSVSYFK_
CCND1	Ubiquitylation	K46	-1.016	-0.036	_AEETCAPSVSYFK(gl)CVQK_
CCND1	Ubiquitylation	K95	-0.733	-0.137	_FLSLEPVK(gl)K_
CCND1	Ubiquitylation	K96	-0.846	-0.155	_FLSLEPVKK(gl)_
CCND1	Ubiquitylation	K238		0.245	_VIK(gl)CDPDCLR_
CTNNA1	Ubiquitylation	K16	-0.194	-0.141	_WDPK(gl)SLEIR_
CTNNA1	Ubiquitylation	K45	-1.131	-0.728	_LLEPLVTQVTTLVNTNSK(gl)GPSNK_
CTNNA1	Ubiquitylation	K120		-0.333	_AAAGEFADDPCSSVK(gl)R_
CTNNA1	Ubiquitylation	K414	0.977		_NGNEK(gl)EVKEYAQVFR_
CTNNA1	Ubiquitylation	K417	0.211		_NGNEK(gl)EVKEYAQVFR_
CTNNA1	Phosphorylation	S641	-0.056	0.089	_TPEELDDS(ph)DFETEDFDVR_
CTNNA1	Phosphorylation	T654	0.808	0.392	_SRT(ph)SVQTEDDQLIAGQSAR_
CTNNA1	Phosphorylation	S655	1.043	0.882	_SRTS(ph)VQTEDDQLIAGQSAR_
CTNNA1	Ubiquitylation	K683	3.760	-0.837	_AIMAQLPQEQKAK(gl)_
CTNNA1	Ubiquitylation	K747		-0.384	_NTSDVISAAK(gl)K_
CTNNA1	Ubiquitylation	K748	-0.083	-0.384	_NTSDVISAAKK(gl)_
CTNNB1	Ubiquitylation	K158		-1.265	_AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1	Ubiquitylation	K180	-0.546	-0.636	_AAVM(ox)VHQLSK(gl)K_
CTNNB1	Ubiquitylation	K181	-0.717	-0.729	_AAVMVHQLSKK(gl)_
CTNNB1	Phosphorylation	S191	-0.024	0.129	_S(ph)PQMVSAIVR_
CTNNB1	Ubiquitylation	K435		-0.350	_NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1	Ubiquitylation	K496		-1.262	_LHYGLPVVVK(gl)_
CTNNB1	Phosphorylation	S552	1.233	1.224	_RTS(ph)MGGTQQQFVEGVR_
CTNNB1	Phosphorylation	T556	1.275	0.995	_RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1	Ubiquitylation	K671	-0.941	-0.934	_MSEDKPQDYK(gl)K_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
ELK1	Phosphorylation	S273	-0.601	-0.553	_PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1	Phosphorylation	S275	-0.601	-0.553	_PAVVLPSAAPAGAAAPPS(ph)GSR_
ELK1	Phosphorylation	S403	0.568	-0.579	_DLELPLS(ph)PSLLGGPGPER_
ERBB2	Ubiquitylation	K200		-2.073	_ACHPCSPMCK(gl)GSR_
ERBB2	Ubiquitylation	K369		-0.742	_AVTSANIQEFAGCKK(gl)_
ERBB2	Ubiquitylation	K747	-0.505	-0.019	_GIWIPDGENVK(gl)IPVAIK_
ERBB2	Ubiquitylation	K854	-0.859		_NVLVK(gl)SPNHVK_
ERBB2	Phosphorylation	S1054	-0.476	-0.706	_S(ph)GGGDLTLGLEPSEEEAPR_
FOXO3	Phosphorylation	S12		-1.324	_(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3	Phosphorylation	S253		2.510	_AVS(ph)MDNSNKYTK_
FOXO3	Phosphorylation	S284	4.138	6.011	_AALQTAPESADDS(ph)PSQLSK_
FOXO3	Phosphorylation	S421		1.295	_GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3	Phosphorylation	S425		1.471	_GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
GSK3B	Phosphorylation	S9	-0.483	0.010	_TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B	Ubiquitylation	K85		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Ubiquitylation	K86		-0.204	_LCDSGELVAIK(gl)K_
GSK3B	Phosphorylation	S215	0.296	0.477	_GEPNVS(ph)YICSR_
GSK3B	Phosphorylation	Y216	0.356	0.376	_GEPNVSY(ph)ICSR_
GSK3B	Phosphorylation	T390	2.800	2.527	_IQAAAST(ph)PTNATAASDANTGDR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
ILK	Ubiquitylation	K85		-0.777	_DIVQK(gl)LLQYK_
ILK	Ubiquitylation	K426		-0.300	_LMK(gl)ICMNEDPAK_
ILK	Ubiquitylation	K435		-2.732	_ICMNEDPAK(gl)RPK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
LEF1	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MYC	Phosphorylation	S20	-1.444	-1.145	_PLNVS(ph)FTNR_
MYC	Phosphorylation	T72	-1.699	-1.813	_FELLPT(ph)PPLS(ph)PSRR_
MYC	Phosphorylation	S76	-1.777	-1.435	_FELLPTPPLS(ph)PSR_
MYC	Phosphorylation	S81		0.459	_S(ph)GLCSPSYVAVTPFSLR_
MYC	Phosphorylation	S85	0.199	0.073	_SGLCS(ph)PSYVAVTPFSLR_
MYC	Ubiquitylation	K162	-2.475	-1.259	_LVSEK(gl)LASYQAAR_
MYC	Phosphorylation	S295		-0.903	_SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC	Phosphorylation	S307		-1.486	_SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC	Ubiquitylation	K340		-2.449	_VK(gl)LDSVR_
MYC	Ubiquitylation	K403		-3.432	_DQIPELENNEK(gl)APK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PDPK1	Phosphorylation	S241	0.358	0.361	_ANS(ph)FVGTAQYVSPELLTEK_
PDPK1	Ubiquitylation	K257	0.571	-0.234	_ANSFVGTAQYVSPELLTEK(gl)SACK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
TCF7	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
TCF7L1	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
TCF7L2	Ubiquitylation	K88	-0.867	-0.222	_ESLEEAAK(gl)R_
TP53	Ubiquitylation	K120	-0.188		_LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53	Ubiquitylation	K164	0.157	-1.260	_AMAIYK(gl)QSQHMTEVVR_
TP53	Phosphorylation	S314	-0.695	-1.000	_ALPNNTSS(ph)SPQPK_
TP53	Phosphorylation	S315	-0.762	-0.959	_RALPNNTSSS(ph)PQPK_
TP53	Ubiquitylation	K320	-0.978		_ALPNNTSSSPQPKK(gl)_
TP53	Ubiquitylation	K357	-0.231	-0.823	_ELNEALELKDAQAGK(gl)EPGGSR_