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Query: CTNNA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTNNA2 0 0.898 0.660 -0.640 -1.825 0.254 0.247
CTNNA2 0 0.898 0.660 -0.640 0.139 0.436 0.323

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CTNNA2:


Pubmed-CTNNA2 »
Uniprot-CTNNA2 »
Biogrid-CTNNA2 »
ProteomicsDB-CTNNA2 »

Tumorportal-CTNNA2 »
COSMIC-CTNNA2 »
GenomeRNAi-CTNNA2 »
Genecards-CTNNA2


Protein-protein Interactions for CTNNA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SDHAF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TYW3 Cat. description Hein, Mann, Cell 2015
Category members IP bait C6orf26 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CIR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTNNBIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DUSP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTNNA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Vinculin/catenin IPR006077 0.27
Category members Alpha_catenin IPR001033 0
Category members Vinculin IPR017997 0


Protein complexes (CORUM database) featuring CTNNA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTNNA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0045296 cadherin binding Database 0.26
Category members GO Category GO:0005912 adherens junction Database 0.25
Category members GO Category GO:0030424 axon Database 0.23
Category members GO Category GO:0048813 dendrite morphogenesis Database 0.23
Category members Pathway Pathway_533 KEGG_ENDOMETRIAL_CANCER 0 0.21
Category members Pathway Pathway_605 KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION 0 0.2
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0021942 radial glia guided migration of Purkinje cell Database 0.13
Category members GO Category GO:0042692 muscle cell differentiation Database 0.1
Category members Pathway Pathway_1178 BIOCARTA_CELL2CELL_PATHWAY 0 0.08
Category members GO Category GO:0051149 positive regulation of muscle cell differentiation Database 0.04
Category members GO Category GO:0016323 basolateral plasma membrane Database 0.04
Category members Pathway Pathway_1007 KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC 0 0.03
Category members Pathway Pathway_24 KEGG_PATHWAYS_IN_CANCER 0 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0048854 brain morphogenesis Database 0
Category members GO Category GO:0051823 regulation of synapse structural plasticity Database 0
Category members GO Category GO:0060134 prepulse inhibition Database 0


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