RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
AKT3	2	0.580	-0.030	-0.194
AKT3	2	0.580	-0.030
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160
CAMK2G	2	-2.070	4.160		-0.654	0.073
CAMK2G	2	-2.070	4.160				0.559	1.698
CAMK2B	1	1.200	-0.790
CAMK2B	1	1.200	-0.790		-0.654	0.073
CAMK2B	1	1.200	-0.790	-0.619			0.544	0.125
CAMK2B	1	1.200	-0.790				0.559	1.698
PIK3R2	1	2.740	-1.180				0.269	0.348
CCND1	1	-1.820	3.470
PLCG1	1	-0.170	0.000
RAF1	1	2.020	-1.230
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
IGF1R	1	-0.490	0.750				1.476	0.714
CALM2	1	-0.690	0.700		1.911
CALM2	1	-0.690	0.700				0.877	-4.680
CALM3	1	-0.190	0.120		1.911
CALM3	1	-0.190	0.120				0.877	-4.680
MAP2K1	1	-1.590	2.780
PDGFA	1	0.190	-0.340		-2.109	1.885
CALM1	1	-0.440	0.360		1.911
CALM1	1	-0.440	0.360				0.877	-4.680
NRAS	1	1.810	-0.720				0.246	-0.346
E2F2	0	0.670	-1.180
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
CAMK2A	0	-0.430	0.130		-0.654	0.073
CAMK2A	0	-0.430	0.130	-0.619			0.544	0.125
ARAF	0	0.550	-0.670
ARAF	0	0.550	-0.670
MAPK3	0
AKT2	0	-1.420	2.210	-0.194
CDK6	0	-0.190	0.160
CDK6	0	-0.190	0.160				-0.510	0.013
E2F3	0	0.000	0.020
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
CDKN1A	0	1.080	-0.750
MAP2K2	0	-0.610	0.080
MAP2K2	0	-0.610	0.080
CDK4	0	1.930	-0.950
CDK4	0	1.930	-0.950				-0.510	0.013
MDM2	0	-0.210	0.080
RB1	0	1.180	-1.070		0.429	0.755
RB1	0	1.180	-1.070
TP53	0	-1.070	1.050	-2.808	0.076	-0.094	0.436	0.497
AKT1	0	-0.050	0.700
AKT1	0	0.860	-0.040
CAMK2D	0	-0.260	0.500		-0.654	0.073
CAMK2D	0	-0.260	0.500	-0.619			0.544	0.125
CAMK2D	0	-0.260	0.500
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
CDKN2A	0	-0.080	-0.260	-0.556		-1.080	-3.270	-1.110
PRKCA	0	0.750	-0.690				0.349	0.585
PRKCA	0	0.750	-0.690
BRAF	0
PRKCB	0	0.260	-0.530
PRKCB	0	0.260	-0.530				0.349	0.585
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
CALML3	0	0.460	-0.670
CALML5	0	-0.980	1.530
MTOR	0	-0.680	0.150	0.757			0.074	0.101

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AKT1	Phosphorylation	S124	0.252	0.311	_SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1	Phosphorylation	S126	-0.241		_SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1	Ubiquitylation	K301	0.988		_EGIK(gl)DGATMK_
AKT2	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT2	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT2	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT2	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT2	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
AKT3	Ubiquitylation	K14	0.306	0.070	_EGWLHK(gl)R_
AKT3	Ubiquitylation	K14	4.941	5.277	_EGWVQK(gl)R_
AKT3	Ubiquitylation	K111	1.082		_AIQMVANSLK(gl)QR_
AKT3	Phosphorylation	S120		1.097	_MNCS(ph)PTSQIDNIGEEEMDASTTHHK_
AKT3	Ubiquitylation	K160		0.251	_LLGK(gl)GTFGK_
AKT3	Phosphorylation	T451	-0.091	-0.612	_YFDDEFTAQSITIT(ph)PPDRYDSLGLLELDQR_
AKT3	Phosphorylation	Y456		-0.265	_YFDDEFTAQSITITPPDRY(ph)DSLGLLELDQR_
ARAF	Phosphorylation	T227		0.017	_STSTPNVHMVSTT(ph)APMDSNLIQLTGQSFSTDAAGSR_
ARAF	Phosphorylation	S260	0.245		_GS(ph)PSPASVSSGR_
ARAF	Ubiquitylation	K543	-1.068	-0.962	_ISSNCPK(gl)AMR_
ARAF	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
BRAF	Phosphorylation	S151	-0.685	-0.629	_SNPKS(ph)PQKPIVR_
BRAF	Phosphorylation	S363	-0.023	-0.241	_S(ph)SSAPNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S365	-0.286	0.012	_SSS(ph)APNVHINTIEPVNIDDLIR_
BRAF	Phosphorylation	S399	-0.890	-0.527	_GDGGSTTGLS(ph)ATPPASLPGSLTNVK_
BRAF	Phosphorylation	T401	-0.525		_GDGGSTTGLSAT(ph)PPASLPGSLTNVK_
BRAF	Phosphorylation	S446	0.246	0.349	_RDS(ph)SDDWEIPDGQITVGQR_
BRAF	Phosphorylation	S447	0.579	0.623	_RDSS(ph)DDWEIPDGQITVGQR_
BRAF	Phosphorylation	S729	0.208	0.219	_SAS(ph)EPSLNR_
CALM1	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM1	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CALM2	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM2	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CALM3	Ubiquitylation	K78	0.061		_DGDGTITTK(gl)ELGTVMR_
CALM3	Ubiquitylation	K142		0.922	_VFDK(gl)DGNGYISAAELR_
CAMK2A	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2B	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2B	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2D	Phosphorylation	S330	0.412	0.370	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T331		-0.174	_KPDGVKES(ph)TESSNTTIEDEDVK_
CAMK2D	Phosphorylation	T336	0.615	0.376	_ESTESSNT(ph)TIEDEDVK_
CAMK2D	Phosphorylation	T337	0.450		_ESTESSNTT(ph)IEDEDVK_
CAMK2G	Ubiquitylation	K147		-1.064	_DLKPENLLLASK(gl)CK_
CAMK2G	Ubiquitylation	K251	-0.437		_DLINK(gl)MLTINPAK_
CAMK2G	Phosphorylation	S365		0.765	_GSTES(ph)CNTTTEDEDLK_
CCND1	Ubiquitylation	K33		-0.490	_AMLK(gl)AEETCAPSVSYFK_
CCND1	Ubiquitylation	K46	-1.016	-0.036	_AEETCAPSVSYFK(gl)CVQK_
CCND1	Ubiquitylation	K95	-0.733	-0.137	_FLSLEPVK(gl)K_
CCND1	Ubiquitylation	K96	-0.846	-0.155	_FLSLEPVKK(gl)_
CCND1	Ubiquitylation	K238		0.245	_VIK(gl)CDPDCLR_
CDK4	Ubiquitylation	K142	-0.552		_DLK(gl)PENILVTSGGTVK_
CDK4	Ubiquitylation	K211	-0.101		_K(gl)PLFCGNSEADQLGK_
CDK4	Phosphorylation	S236		0.095	_QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4	Phosphorylation	S249		0.095	_QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4	Ubiquitylation	K297	0.247	0.052	_ALQHSYLHK(gl)DEGNPE_
CDK4	Phosphorylation	S385		0.649	_HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4	Phosphorylation	S420	0.004	-0.202	_ES(ph)KGSPVFLPR_
CDK4	Phosphorylation	S423	-0.155	-0.297	_GS(ph)PVFLPR_
CDK4	Phosphorylation	T514	0.364	0.570	_DSKPIALKEEIVT(ph)PK_
CDK4	Phosphorylation	S681	-2.532	-2.051	_HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4	Phosphorylation	S685		-2.729	_HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4	Phosphorylation	T692	-0.765	-1.849	_AIT(ph)PPQQPYK_
CDK4	Phosphorylation	S1082	-1.661	-0.980	_KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4	Phosphorylation	S1083	-1.093	-1.330	_NSS(ph)PAPPQPAPGK_
CDK4	Phosphorylation	T1244		-0.956	_RT(ph)PTMPQEEAAACPPHILPPEK_
CDK6	Ubiquitylation	K3	0.121	0.039	_(ac)MEK(gl)DGLCR_
CDK6	Phosphorylation	S236		0.095	_QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6	Phosphorylation	S249		0.095	_QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6	Phosphorylation	S385		0.649	_HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6	Phosphorylation	S420	0.004	-0.202	_ES(ph)KGSPVFLPR_
CDK6	Phosphorylation	S423	-0.155	-0.297	_GS(ph)PVFLPR_
CDK6	Phosphorylation	T514	0.364	0.570	_DSKPIALKEEIVT(ph)PK_
CDK6	Phosphorylation	S681	-2.532	-2.051	_HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6	Phosphorylation	S685		-2.729	_HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6	Phosphorylation	T692	-0.765	-1.849	_AIT(ph)PPQQPYK_
CDK6	Phosphorylation	S1082	-1.661	-0.980	_KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6	Phosphorylation	S1083	-1.093	-1.330	_NSS(ph)PAPPQPAPGK_
CDK6	Phosphorylation	T1244		-0.956	_RT(ph)PTMPQEEAAACPPHILPPEK_
CDKN1A	Ubiquitylation	K188	-2.505	-1.077	_QTSMTDFYHSK(gl)R_
E2F2	Ubiquitylation	K188		-0.267	_TRYDTSLGLLTK(gl)K_
E2F2	Ubiquitylation	K189		-0.267	_TRYDTSLGLLTK(gl)K_
E2F3	Ubiquitylation	K188		-0.267	_TRYDTSLGLLTK(gl)K_
E2F3	Ubiquitylation	K189		-0.267	_TRYDTSLGLLTK(gl)K_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
IGF1R	Ubiquitylation	K47		1.146	_NDYQQLK(gl)R_
IGF1R	Ubiquitylation	K1033	5.779		_VAIK(gl)TVNEAASMR_
IGF1R	Ubiquitylation	K1168	0.191		_K(gl)GGKGLLPVR_
IGF1R	Ubiquitylation	K1171	0.232		_GGK(gl)GLLPVR_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAP2K1	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K1	Phosphorylation	S385		0.066	_RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1	Phosphorylation	T386		0.377	_RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAP2K2	Phosphorylation	S23	0.873	0.258	_RKPVLPALTINPTIAEGPS(ph)PTSEGASEANLVDLQK_
MAP2K2	Phosphorylation	T25		0.439	_RKPVLPALTINPTIAEGPSPT(ph)SEGASEANLVDLQK_
MAP2K2	Ubiquitylation	K192	-0.205	-0.241	_DVK(gl)PSNILVNSR_
MAP2K2	Phosphorylation	S293		-0.361	_ELEAIFGRPVVDGEEGEPHS(ph)ISPR_
MAP2K2	Phosphorylation	S295	-0.234	0.026	_ELEAIFGRPVVDGEEGEPHSIS(ph)PR_
MAP2K2	Phosphorylation	T394	0.570	0.158	_LNQPGT(ph)PTR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
MDM2	Phosphorylation	S166	0.576	1.068	_AIS(ph)ETEENSDELSGER_
MDM2	Ubiquitylation	K334		-0.872	_ENWLPEDK(gl)GK_
MDM2	Ubiquitylation	K336		-0.872	_ENWLPEDK(gl)GK_
MDM2	Ubiquitylation	K363		0.883	_LENSTQAEEGFDVPDCK(gl)K_
MDM2	Ubiquitylation	K364		0.883	_LENSTQAEEGFDVPDCK(gl)K_
MDM2	Ubiquitylation	K473		0.806	_NK(gl)PCPVCR_
MTOR	Ubiquitylation	K309	-0.762	0.065	_DLMGFGTK(gl)PR_
MTOR	Ubiquitylation	K1257	-1.167	-0.901	_SGQGDALASGPVETGPMKK(gl)_
MTOR	Ubiquitylation	K1395		-1.255	_AYAK(gl)ALHYK_
MTOR	Ubiquitylation	K2066		-1.004	_GPQTLK(gl)ETSFNQAYGR_
MTOR	Ubiquitylation	K2166		-1.304	_IQSIAPSLQVITSK(gl)QRPR_
MTOR	Phosphorylation	T2471		0.329	_KT(ph)GTTVPESIHSFIGDGLVKPEALNK_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PRKCA	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCA	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCA	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCA	Ubiquitylation	K316	-0.522	-0.535	_LGPAGNK(gl)VISPSEDR_
PRKCB	Phosphorylation	S10	-0.650	0.036	_(ac)ADVFPGNDS(ph)TASQDVANR_
PRKCB	Phosphorylation	S13	-1.038	0.335	_(ac)ADVFPGNDSTAS(ph)QDVANR_
PRKCB	Phosphorylation	S226	0.693	0.415	_STLNPQWNES(ph)FTFK_
PRKCB	Ubiquitylation	K315	0.213	0.518	_ISQGTK(gl)VPEEK_
RAF1	Phosphorylation	S29	0.028	-0.571	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	T31	0.028	-0.669	_DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1	Phosphorylation	S244		0.053	_YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1	Phosphorylation	S259	-0.069	0.054	_STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1	Phosphorylation	S301		-0.651	_SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1	Phosphorylation	T303		-0.664	_SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1	Phosphorylation	S497		-0.449	_SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1	Phosphorylation	S621	0.212	0.271	_SAS(ph)EPSLHR_
RAF1	Phosphorylation	S642	-0.197	0.463	_AAHTEDINACTLTTS(ph)PR_
RB1	Phosphorylation	S69	-3.602	-3.397	_TAATAAAAAAEPPAPPPPPPPEEDPEQDS(ph)GPEDLPLVR_
RB1	Ubiquitylation	K97	-0.546		_LK(gl)IPDHVR_
RB1	Phosphorylation	T388	0.005	0.116	_TLQTDSIDSFETQRT(ph)PR_
RB1	Phosphorylation	T405	-0.851	-0.901	_KSNLDEEVNVIPPHT(ph)PVR_
RB1	Phosphorylation	S820		-0.019	_S(ph)PYKFPSSPLR_
RB1	Ubiquitylation	K823	-2.214		_SPYK(gl)FPSSPLR_
RB1	Phosphorylation	S827	0.824	0.111	_FPSS(ph)PLR_
RB1	Phosphorylation	S839	-0.701	-1.045	_IPGGNIYIS(ph)PLKS(ph)PYK_
RB1	Ubiquitylation	K842		-0.751	_IPGGNIYISPLK(gl)SPYK_
RB1	Phosphorylation	S843	-0.701	-0.022	_IPGGNIYIS(ph)PLKS(ph)PYK_
RB1	Ubiquitylation	K846	-2.084		_SPYK(gl)ISEGLPTPTK_
RB1	Phosphorylation	T853	0.039	-0.555	_ISEGLPT(ph)PTKM(ox)T(ph)PR_
RB1	Ubiquitylation	K856	-1.350		_ISEGLPTPTK(gl)MTPR_
RB1	Phosphorylation	T858	-0.782	0.564	_ISEGLPT(ph)PTKMT(ph)PR_
RB1	Ubiquitylation	K879	-0.187		_FQK(gl)INQMVCNSDR_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
TP53	Ubiquitylation	K120	-0.188		_LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53	Ubiquitylation	K164	0.157	-1.260	_AMAIYK(gl)QSQHMTEVVR_
TP53	Phosphorylation	S314	-0.695	-1.000	_ALPNNTSS(ph)SPQPK_
TP53	Phosphorylation	S315	-0.762	-0.959	_RALPNNTSSS(ph)PQPK_
TP53	Ubiquitylation	K320	-0.978		_ALPNNTSSSPQPKK(gl)_
TP53	Ubiquitylation	K357	-0.231	-0.823	_ELNEALELKDAQAGK(gl)EPGGSR_