RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
INSR	2	-0.850	0.830				1.143	0.785
PIK3R2	1	2.740	-1.180				0.269	0.348
EIF2A	1	-0.180	-0.460	-0.199			-1.243	-0.618
STAT6	1	2.310	-1.150		-0.421	-0.069
ATR	1	-1.040	0.920	0.671			1.041	0.708
CREBBP	0	0.840	-0.950				-3.889	-1.071
PIAS1	0	-1.020	1.720	-1.034	-0.678	0.471	-0.051	1.019
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
EIF2AK2	0	-1.060	1.180	-0.657		-0.502	0.213	-0.027
LMAN1	0						0.562	0.393
LMAN1	0
MET	0	-0.010	-0.330
KPNB1	0	-1.100	2.030	0.513	-0.057	0.327	0.627	0.452
GAB1	0	1.950	-1.110
STAT1	0	-0.550	0.170
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
KDR	0	0.860	-0.680
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
ITGB1	0	0.390	-0.650				0.101	-0.036
JAK1	0	0.190	-0.100		-1.504	-0.381		-0.438
STAT3	0	0.200	-1.270					0.334
STAT5B	0	0.670	-0.960
PTPN2	0	1.210	-0.730
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PTPN1	0	-0.150	0.310	1.066	0.459	0.251	0.322	0.379
SRC	0	0.050	0.470	-0.031
ITGA1	0	-0.750	1.480				0.650	0.069

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ATR	Ubiquitylation	K32		-0.929	_ELGSATPEEYNTVVQK(gl)PR_
ATR	Phosphorylation	S435	0.516	0.284	_RLS(ph)SSLNPSK_
ATR	Ubiquitylation	K746		-1.823	_NLK(gl)ATSQHECSSSQLK_
ATR	Ubiquitylation	K1019	1.662		_TLGK(gl)QLNVNRR_
ATR	Ubiquitylation	K1600	-0.437		_FQALK(gl)AEK_
ATR	Ubiquitylation	K2106		-0.136	_AYEWEK(gl)AGR_
ATR	Ubiquitylation	K2604	0.657	1.118	_LQGVIK(gl)TR_
CREBBP	Phosphorylation	S2093	0.037	0.097	_SIS(ph)PSALQDLLR_
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
EIF2A	Ubiquitylation	K40		7.150	_NCK(gl)VCIFSK_
EIF2A	Phosphorylation	S503	-0.843	-0.645	_S(ph)DKSPDLAPTPAPQSTPR_
EIF2A	Phosphorylation	S506	-0.882	-0.939	_SDKS(ph)PDLAPTPAPQSTPR_
EIF2AK2	Phosphorylation	S83		0.256	_KAVS(ph)PLLLTTTNSSEGLSMGNYIGLINR_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
INSR	Ubiquitylation	K1022	-0.603		_EK(gl)ITLLR_
INSR	Ubiquitylation	K1047	0.305	0.711	_DIIK(gl)GEAETR_
INSR	Ubiquitylation	K1057	0.482	0.484	_VAVK(gl)TVNESASLR_
INSR	Ubiquitylation	K1352	1.606	2.754	_DGGSSLGFK(gl)R_
ITGB1	Ubiquitylation	K774	0.402		_MNAK(gl)WDTGENPIYK_
ITGB1	Ubiquitylation	K784	-0.172	0.350	_WDTGENPIYK(gl)SAVTTVVNPK_
ITGB1	Ubiquitylation	K794	0.755	0.604	_SAVTTVVNPK(gl)YEGK_
JAK1	Ubiquitylation	K227	-0.405		_YIPETLNK(gl)SIR_
JAK1	Ubiquitylation	K249	0.116	0.771	_DFLK(gl)EFNNK_
JAK1	Ubiquitylation	K559	-0.478		_EISNLLVATK(gl)K_
KDR	Ubiquitylation	K1064		-1.119	_DIYK(gl)DPDYVR_
KPNB1	Ubiquitylation	K68	0.403	0.420	_NSLTSK(gl)DPDIK_
KPNB1	Ubiquitylation	K73		-0.134	_NSLTSKDPDIK(gl)AQYQQR_
KPNB1	Ubiquitylation	K211	-0.036		_ANFDK(gl)ESER_
KPNB1	Ubiquitylation	K549	-0.563		_DCYPAVQK(gl)TTLVIMER_
KPNB1	Ubiquitylation	K835	-0.212	0.450	_DVLK(gl)LVEAR_
KPNB1	Ubiquitylation	K859		0.118	_AK(gl)TLATWATK_
KPNB1	Ubiquitylation	K867	0.636	1.498	_TLATWATK(gl)ELR_
LMAN1	Ubiquitylation	K96		0.601	_GSVWTK(gl)TK_
LMAN1	Ubiquitylation	K346	-0.443		_IHLEIK(gl)QLNR_
LMAN1	Ubiquitylation	K372	1.187	0.921	_YVSSLTEEISK(gl)R_
LMAN1	Ubiquitylation	K407		0.987	_QVNEMK(gl)NSMSETVR_
LMAN1	Ubiquitylation	K463		-0.810	_NMPSNEK(gl)PK_
LMAN1	Ubiquitylation	K465		-0.810	_NMPSNEK(gl)PK_
MET	Ubiquitylation	K962	0.146		_QIK(gl)DLGSELVR_
MET	Phosphorylation	S988	0.064		_S(ph)VSPTTEM(ox)VSNESVDYR_
MET	Phosphorylation	S990	0.192	-0.105	_SVS(ph)PTTEM(ox)VSNESVDYR_
MET	Phosphorylation	T992	0.501	-0.048	_SVSPT(ph)TEMVSNESVDYR_
MET	Phosphorylation	S997		0.285	_S(ph)VSPTTEMVS(ph)NESVDYR_
PIAS1	Ubiquitylation	K60		-1.191	_AGCSPAVQMKIK(gl)_
PIAS1	Ubiquitylation	K341		-1.248	_VSLLCPLGK(gl)MR_
PIAS1	Phosphorylation	S490	-0.898	-0.944	_RTCPSLSPTS(ph)PLNNK_
PIAS1	Phosphorylation	S505	0.198	-0.250	_GILSLPHQAS(ph)PVSR_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PTPN1	Phosphorylation	S352		0.032	_GS(ph)PLNAAPYGIESMSQDTEVR_
PTPN1	Phosphorylation	S365	-0.247	0.956	_GSPLNAAPYGIESMS(ph)QDTEVR_
PTPN1	Phosphorylation	S378	1.462	1.262	_VVGGS(ph)LR_
PTPN2	Phosphorylation	S304	-0.873	-0.641	_ELSKEDLSPAFDHS(ph)PNK_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B	Phosphorylation	S194		0.270	_IQAQFGPLAQLS(ph)PQER_