bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: EIF2A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF2A 1 3.602 -0.180 -0.460 -0.199 -1.243 -0.618

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF2A Ubiquitylation K40 7.150 _NCK(gl)VCIFSK_
EIF2A Phosphorylation S503 -0.843 -0.645 _S(ph)DKSPDLAPTPAPQSTPR_
EIF2A Phosphorylation S506 -0.882 -0.939 _SDKS(ph)PDLAPTPAPQSTPR_

Background Information for EIF2A:


Pubmed-EIF2A »
Uniprot-EIF2A »
Biogrid-EIF2A »
ProteomicsDB-EIF2A »

Tumorportal-EIF2A »
COSMIC-EIF2A »
GenomeRNAi-EIF2A »
Genecards-EIF2A


Protein-protein Interactions for EIF2A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CYP1A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF2E2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP27 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SSSCA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF2A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members TIF_beta_prop-like IPR013979 1.21


Protein complexes (CORUM database) featuring EIF2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EIF2A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0042255 ribosome assembly Database 1.46
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members Pathway Pathway_933 PID_TGFBR_PATHWAY 0 0.52
Category members GO Category GO:0005850 eukaryotic translation initiation factor 2 complex Database 0.46
Category members GO Category GO:0043022 ribosome binding Database 0.33
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members Pathway Pathway_593 PID_TCPTP_PATHWAY 0 0
Category members Pathway Pathway_734 PID_CERAMIDE_PATHWAY 0 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0006417 regulation of translation Database 0
Category members GO Category GO:0009967 positive regulation of signal transduction Database 0
Category members GO Category GO:0032933 SREBP signaling pathway Database 0


.

© Copyright Svejstrup Laboratory 2015