Results for the Category
SREBP signaling pathway
(GO:0032933)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| SCAP | 1 | -1.960 | 2.960 | |||||
| INSIG2 | 1 | -0.190 | -0.120 | |||||
| EIF2A | 1 | -0.180 | -0.460 | -0.199 | -1.243 | -0.618 | ||
| EIF2AK3 | 0 | 0.010 | 0.340 | |||||
| INSIG1 | 0 | 0.090 | -0.390 | |||||
| INSIG1 | 0 | 0.090 | -0.390 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| EIF2A | Ubiquitylation | K40 | 7.150 | _NCK(gl)VCIFSK_ | |
| EIF2A | Phosphorylation | S503 | -0.843 | -0.645 | _S(ph)DKSPDLAPTPAPQSTPR_ |
| EIF2A | Phosphorylation | S506 | -0.882 | -0.939 | _SDKS(ph)PDLAPTPAPQSTPR_ |
| EIF2AK3 | Phosphorylation | S715 | 0.832 | _EHIEIIAPS(ph)PQR_ | |
| INSIG1 | Ubiquitylation | K273 | -1.588 | _QLAMGVPEK(gl)PHSD_ | |
| INSIG1 | Ubiquitylation | K305 | -2.056 | _SPIVIESSK(gl)PPILR_ | |
| INSIG2 | Ubiquitylation | K221 | 1.628 | _VIAEK(gl)SHQE_ | |
| SCAP | Phosphorylation | S851 | -1.348 | -1.502 | _AGPEEPGDS(ph)PPLR_ |
| SCAP | Phosphorylation | S937 | -0.711 | -1.037 | _VYQEEGLAAVCTPALRPPS(ph)PGPVLSQAPEDEGGSPEK_ |
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