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Query: INSIG2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INSIG2 1 1.508 -0.190 -0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INSIG2 Ubiquitylation K221 1.628 _VIAEK(gl)SHQE_

Background Information for INSIG2:


Pubmed-INSIG2 »
Uniprot-INSIG2 »
Biogrid-INSIG2 »
ProteomicsDB-INSIG2 »

Tumorportal-INSIG2 »
COSMIC-INSIG2 »
GenomeRNAi-INSIG2 »
Genecards-INSIG2


Protein-protein Interactions for INSIG2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in INSIG2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members INSIG_fam IPR025929 0


Protein complexes (CORUM database) featuring INSIG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring INSIG2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0032937 SREBP-SCAP-Insig complex Database 0.09
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members GO Category GO:0045717 negative regulation of fatty acid biosynthetic process Database 0.02
Category members GO Category GO:0006641 triglyceride metabolic process Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0006991 response to sterol depletion Database 0
Category members GO Category GO:0010894 negative regulation of steroid biosynthetic process Database 0
Category members GO Category GO:0016126 sterol biosynthetic process Database 0
Category members GO Category GO:0032868 response to insulin Database 0
Category members GO Category GO:0032933 SREBP signaling pathway Database 0
Category members GO Category GO:0033993 response to lipid Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0042474 middle ear morphogenesis Database 0
Category members GO Category GO:0060363 cranial suture morphogenesis Database 0
Category members GO Category GO:0070542 response to fatty acid Database 0


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