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Query: SCAP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SCAP 1 1.212 -1.960 2.960

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SCAP Phosphorylation S937 -0.711 -1.037 _VYQEEGLAAVCTPALRPPS(ph)PGPVLSQAPEDEGGSPEK_
SCAP Phosphorylation S851 -1.348 -1.502 _AGPEEPGDS(ph)PPLR_

Background Information for SCAP:


Pubmed-SCAP »
Uniprot-SCAP »
Biogrid-SCAP »
ProteomicsDB-SCAP »

Tumorportal-SCAP »
COSMIC-SCAP »
GenomeRNAi-SCAP »
Genecards-SCAP


Protein-protein Interactions for SCAP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait B3GNT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCOLN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNRF4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SCAP
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members SSD IPR000731 0.17
Category members Patched IPR003392 0.09


Protein complexes (CORUM database) featuring SCAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1990 PGRMC1-SCAP complex Database 0


Categories featuring SCAP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0008203 cholesterol metabolic process Database 0.08
Category members GO Category GO:0008158 hedgehog receptor activity Database 0.04
Category members Pathway Pathway_959 SA_CASPASE_CASCADE 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0007568 aging Database 0
Category members GO Category GO:0012507 ER to Golgi transport vesicle membrane Database 0
Category members GO Category GO:0019217 regulation of fatty acid metabolic process Database 0
Category members GO Category GO:0032868 response to insulin Database 0
Category members GO Category GO:0032933 SREBP signaling pathway Database 0
Category members GO Category GO:0042304 regulation of fatty acid biosynthetic process Database 0
Category members GO Category GO:0045540 regulation of cholesterol biosynthetic process Database 0
Category members GO Category GO:0045541 negative regulation of cholesterol biosynthetic process Database 0
Category members GO Category GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process Database 0


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