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Query: LMAN1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LMAN1 0 3.130
LMAN1 0 3.130 0.562 0.393

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LMAN1 Ubiquitylation K407 0.987 _QVNEMK(gl)NSMSETVR_
LMAN1 Ubiquitylation K372 1.187 0.921 _YVSSLTEEISK(gl)R_
LMAN1 Ubiquitylation K96 0.601 _GSVWTK(gl)TK_
LMAN1 Ubiquitylation K463 -0.810 _NMPSNEK(gl)PK_
LMAN1 Ubiquitylation K465 -0.810 _NMPSNEK(gl)PK_
LMAN1 Ubiquitylation K346 -0.443 _IHLEIK(gl)QLNR_

Background Information for LMAN1:


Pubmed-LMAN1 »
Uniprot-LMAN1 »
Biogrid-LMAN1 »
ProteomicsDB-LMAN1 »

Tumorportal-LMAN1 »
COSMIC-LMAN1 »
GenomeRNAi-LMAN1 »
Genecards-LMAN1


Protein-protein Interactions for LMAN1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C6orf72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LMAN1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HMG_box_dom IPR009071 0.31
Category members Lectin_leg IPR005052 0
Category members ConA-like_lec_gl_sf IPR008985 0


Protein complexes (CORUM database) featuring LMAN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LMAN1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0051082 unfolded protein binding Database 3.74
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005793 endoplasmic reticulum-Golgi intermediate compartment Database 0.74
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0007030 Golgi organization Database 0.13
Category members GO Category GO:0005537 mannose binding Database 0.07
Category members GO Category GO:0030017 sarcomere Database 0.06
Category members GO Category GO:0007029 endoplasmic reticulum organization Database 0.05
Category members GO Category GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane Database 0.05
Category members Pathway Pathway_115 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION 0 0
Category members Pathway Pathway_593 PID_TCPTP_PATHWAY 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members Disease phenotype Combined_deficiency_of_factor_V_and_factor_VIII Combined deficiency of factor V and factor VIII Database 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0010638 positive regulation of organelle organization Database 0
Category members GO Category GO:0012507 ER to Golgi transport vesicle membrane Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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