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Query: STAT6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
STAT6 1 0.000 2.310 -1.150 -0.421 -0.069

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for STAT6:


Pubmed-STAT6 »
Uniprot-STAT6 »
Biogrid-STAT6 »
ProteomicsDB-STAT6 »

Tumorportal-STAT6 »
COSMIC-STAT6 »
GenomeRNAi-STAT6 »
Genecards-STAT6


Protein-protein Interactions for STAT6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF22 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015


Protein Domains in STAT6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH2 IPR000980 0.05
Category members STAT_TF_prot_interaction IPR013799 0.03
Category members STAT_TF_alpha IPR013800 0.03
Category members STAT_TF_DNA-bd IPR013801 0.03
Category members p53-like_TF_DNA-bd IPR008967 0
Category members STAT_TF_coiled-coil IPR015988 0


Protein complexes (CORUM database) featuring STAT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3129 STAT6-p100-RHA complex Database 0


Categories featuring STAT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_255 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION 0 0.42
Category members Pathway Pathway_247 REACTOME_SIGNALING_BY_PDGF 0 0.4
Category members GO Category GO:0019903 protein phosphatase binding Database 0.33
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_447 KEGG_JAK_STAT_SIGNALING_PATHWAY 0 0.13
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0033598 mammary gland epithelial cell proliferation Database 0.09
Category members Pathway Pathway_578 BIOCARTA_EGF_PATHWAY 0 0.09
Category members GO Category GO:0042127 regulation of cell proliferation Database 0.06
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding Database 0.05
Category members Pathway Pathway_630 BIOCARTA_PDGF_PATHWAY 0 0.03
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0070301 cellular response to hydrogen peroxide Database 0
Category members Pathway Pathway_1181 BIOCARTA_IL22BP_PATHWAY 0 0
Category members Pathway Pathway_410 ST_INTERLEUKIN_4_PATHWAY 0 0
Category members Pathway Pathway_419 PID_IL4_2PATHWAY 0 0
Category members Pathway Pathway_423 PID_IL12_2PATHWAY 0 0
Category members Pathway Pathway_593 PID_TCPTP_PATHWAY 0 0
Category members Pathway Pathway_633 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES 0 0
Category members Pathway Pathway_704 BIOCARTA_BIOPEPTIDES_PATHWAY 0 0
Category members Pathway Pathway_749 BIOCARTA_IL10_PATHWAY 0 0
Category members Pathway Pathway_989 BIOCARTA_IL4_PATHWAY 0 0
Category members Disease phenotype Solitary_fibrous_tumor Solitary fibrous tumor Database 0
Category members GO Category GO:0002296 T-helper 1 cell lineage commitment Database 0
Category members GO Category GO:0002829 negative regulation of type 2 immune response Database 0
Category members GO Category GO:0004871 signal transducer activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0034097 response to cytokine Database 0
Category members GO Category GO:0035771 interleukin-4-mediated signaling pathway Database 0
Category members GO Category GO:0048295 positive regulation of isotype switching to IgE isotypes Database 0
Category members GO Category GO:0060443 mammary gland morphogenesis Database 0


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