RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
SH2D4A	2	-0.130	0.140
FYN	1	1.080	-1.100
FYN	1	1.080	-1.100
PIK3R2	1	2.740	-1.180				0.269	0.348
PLCG1	1	-0.170	0.000
TNS3	1	-1.690	2.670
STAT6	1	2.310	-1.150		-0.421	-0.069
LYN	1	-1.790	3.770
LYN	1	-1.790	3.770
NCK2	0	-0.870	1.530
ABL1	0	0.670	-0.070
CRKL	0	0.290	-0.620
PTK6	0	-0.300	0.700	0.520	0.139	1.329	0.365	0.320
CSK	0	1.200	-0.960	-1.211
CSK	0	1.200	-0.960
GRB10	0	0.900	-0.860
SUPT6H	0	0.030	-0.700	1.341	-0.537	1.060	-1.444	0.939
STAT1	0	-0.550	0.170
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
ABL2	0	0.050	-0.340
PIK3R1	0	1.910	-1.220				-0.441	0.147
FER	0	0.540	-0.510		0.407
NCK1	0	-0.370	0.580
JAK1	0	0.190	-0.100		-1.504	-0.381		-0.438
INPPL1	0	1.690	-0.810
CRK	0	-0.790	0.230
STAT3	0	0.200	-1.270					0.334
STAT5B	0	0.670	-0.960
YES1	0	0.340	-0.470				0.295	0.576
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
SH2B1	0	0.970	0.010
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451
LCK	0	-0.490	1.390				0.295	0.576
SH2D5	0	0.850	-0.040
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ABL1	Phosphorylation	S1083	-1.131	-0.857	_GQGESDPLDHEPAVS(ph)PLLPR_
ABL1	Phosphorylation	S1134		0.293	_SSS(ph)FREMDGQPER_
ABL1	Phosphorylation	S1232	0.821	0.183	_SCS(ph)ASCVPHGAK_
ABL2	Phosphorylation	S618	-0.733		_GAQASS(ph)GSPALPR_
ABL2	Phosphorylation	S620	0.568	0.091	_GAQASSGS(ph)PALPR_
ABL2	Phosphorylation	S631	0.529	0.416	_DKS(ph)PSSLLEDAK_
ABL2	Phosphorylation	S634	0.322		_DKSPSS(ph)LLEDAK_
ABL2	Phosphorylation	S781	0.421		_S(ph)NSTSSM(ox)SSGLPEQDR_
ABL2	Phosphorylation	S783	-0.171		_SNS(ph)TSSMSSGLPEQDR_
ABL2	Phosphorylation	S817	0.028	0.055	_TVS(ph)TSSQPEENVDR_
ABL2	Phosphorylation	S936	-0.218	-0.547	_VPVLIS(ph)PTLK_
CRK	Phosphorylation	S40	0.533	0.363	_DS(ph)STSPGDYVLSVSENSR_
CRK	Phosphorylation	S41	1.065	0.801	_DSS(ph)TSPGDYVLSVSENSR_
CRKL	Phosphorylation	S41		0.868	_DS(ph)STCPGDYVLSVSENSR_
CRKL	Phosphorylation	S107	-0.818	-1.177	_YPS(ph)PPMGSVSAPNLPTAEDNLEYVR_
CSK	Ubiquitylation	K196	-0.133		_SGWALNMKELK(gl)_
FYN	Ubiquitylation	K13	0.286		_DKEATK(gl)LTEER_
FYN	Phosphorylation	S21	0.373	0.731	_DGS(ph)LNQSSGYR_
FYN	Ubiquitylation	K259		0.921	_LTDLSVK(gl)TK_
FYN	Ubiquitylation	K261	0.099		_LTDLSVKTK(gl)_
FYN	Ubiquitylation	K273	6.025		_SLCLEKK(gl)_
FYN	Ubiquitylation	K275	-0.521		_ESLQLIK(gl)R_
GRB10	Phosphorylation	S104	-0.985	-0.688	_SIQPQVS(ph)PR_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
INPPL1	Phosphorylation	S1003	-1.290		_NSFNNPAYYVLEGVPHQLLPPEPPS(ph)PAR_
JAK1	Ubiquitylation	K227	-0.405		_YIPETLNK(gl)SIR_
JAK1	Ubiquitylation	K249	0.116	0.771	_DFLK(gl)EFNNK_
JAK1	Ubiquitylation	K559	-0.478		_EISNLLVATK(gl)K_
LCK	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
LCK	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
LCK	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
LCK	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_
LYN	Ubiquitylation	K20	-0.592		_GKDSLSDDGVDLK(gl)TQPVR_
LYN	Ubiquitylation	K40	0.100		_DPTSNK(gl)QQRPVPESQLLPGQR_
LYN	Phosphorylation	S104	0.944	0.841	_DSLS(ph)DDGVDLK_
LYN	Ubiquitylation	K213	0.441		_HYQK(gl)QADGLCR_
LYN	Ubiquitylation	K477	-0.191		_VENCPDELYDIMK(gl)MCWK_
NCK1	Phosphorylation	S85	-0.027	-0.877	_RKPS(ph)VPDSASPADDSFVDPGER_
NCK1	Phosphorylation	S91		0.493	_RKPSVPDSAS(ph)PADDSFVDPGER_
NCK2	Phosphorylation	S90	-0.317	0.054	_DAS(ph)PTPSTDAEYPANGSGADR_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PTK6	Phosphorylation	S47	0.375	0.573	_RDS(ph)LEEGELR_
PTK6	Phosphorylation	T61		0.721	_MEIT(ph)IRNSPYR_
PTK6	Phosphorylation	S65	0.730	0.552	_MEITIRNS(ph)PYR_
PTK6	Phosphorylation	S234	-0.737	-0.712	_S(ph)PPRPPR_
PTK6	Phosphorylation	S283	0.324	0.483	_DLLSDLQDIS(ph)DSER_
PTK6	Ubiquitylation	K467		-0.286	_TDEIVALK(gl)R_
PTK6	Phosphorylation	S589	0.529	0.585	_EYGS(ph)PLKAYT(ph)PVVVTLWYR_
PTK6	Phosphorylation	T595	0.472	0.397	_AYT(ph)PVVVTLWYR_
PTK6	Ubiquitylation	K672		-1.465	_IWPGYSELPAVK(gl)K_
PTK6	Ubiquitylation	K673		-1.465	_IWPGYSELPAVK(gl)K_
PTK6	Ubiquitylation	K719		-0.672	_ISAEDGLK(gl)HEYFR_
PTK6	Phosphorylation	T751	-0.349	-0.460	_RGT(ph)SPRPPEGGLGYSQLGDDDLK_
PTK6	Phosphorylation	S752	-0.526	-0.643	_RGTS(ph)PRPPEGGLGYSQLGDDDLK_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
SH2B1	Phosphorylation	S96	0.112	-0.143	_ASGSLSPPILAPLS(ph)PGAEISPHDLSLESCR_
SH2B1	Phosphorylation	S125	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SH2B1	Phosphorylation	S126	0.018	0.257	_S(ph)SEDLAGPLPSSVSSSSTTSSKPK_
SH2D4A	Phosphorylation	S315	1.655	1.510	_TLS(ph)SSAQEDIIR_
SH2D5	Phosphorylation	S231	1.238	-0.003	_LGNPYCS(ph)PTLVR_
SH2D5	Phosphorylation	T233	-0.221		_LGNPYCSPT(ph)LVR_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B	Phosphorylation	S194		0.270	_IQAQFGPLAQLS(ph)PQER_
SUPT6H	Phosphorylation	S12	0.206	0.455	_(ac)SDFVESEAEES(ph)EEEYNDEGEVVPR_
SUPT6H	Ubiquitylation	K622	-0.598		_LNITPTK(gl)K_
SUPT6H	Ubiquitylation	K623	-0.598		_LNITPTK(gl)K_
SUPT6H	Phosphorylation	T1523	-0.262	-0.132	_DHYQDPVPGIT(ph)PSSSSR_
SUPT6H	Phosphorylation	T1530	-0.310	0.405	_T(ph)RTPASINATPANINLADLTR_
SUPT6H	Phosphorylation	T1532	0.190	0.451	_TRT(ph)PASINATPANINLADLTR_
SUPT6H	Phosphorylation	S1535	0.272		_TRTPAS(ph)INATPANINLADLTR_
SUPT6H	Phosphorylation	S1701		-0.630	_LTPRPS(ph)PSPMIESTPMSIAGDAT(ph)PLLDEMDR_
SUPT6H	Phosphorylation	T1718		-0.789	_LTPRPS(ph)PSPMIESTPMSIAGDAT(ph)PLLDEMDR_
TNS3	Phosphorylation	S776	1.240	-0.070	_LS(ph)LGQYDNDAGGQLPFSK_
YES1	Phosphorylation	T37		-0.435	_YRPENTPEPVSTSVSHYGAEPT(ph)TVSPCPSSSAK_
YES1	Ubiquitylation	K191	-0.112	0.264	_ESETTK(gl)GAYSLSIR_
YES1	Ubiquitylation	K235	0.323		_AQFDTLQK(gl)LVK_
YES1	Ubiquitylation	K259		-1.613	_LTTVCPTVK(gl)PQTQGLAK_