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Query: FER

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FER 0 0.000 0.540 -0.510 0.407

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for FER:


Pubmed-FER »
Uniprot-FER »
Biogrid-FER »
ProteomicsDB-FER »

Tumorportal-FER »
COSMIC-FER »
GenomeRNAi-FER »
Genecards-FER


Protein-protein Interactions for FER
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FER
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SH2 IPR000980 0.05
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members FCH_dom IPR001060 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring FER
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FER
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0005938 cell cortex Database 2.26
Category members GO Category GO:0015629 actin cytoskeleton Database 2.22
Category members GO Category GO:0030027 lamellipodium Database 1.77
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0032869 cellular response to insulin stimulus Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members Pathway Pathway_599 REACTOME_SIGNALING_BY_SCF_KIT 0 0.48
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members Pathway Pathway_747 KEGG_ADHERENS_JUNCTION 0 0.43
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0038095 Fc-epsilon receptor signaling pathway Database 0.36
Category members GO Category GO:0032496 response to lipopolysaccharide Database 0.35
Category members GO Category GO:0010591 regulation of lamellipodium assembly Database 0.31
Category members GO Category GO:0031532 actin cytoskeleton reorganization Database 0.29
Category members Pathway Pathway_562 PID_NCADHERIN_PATHWAY 0 0.29
Category members GO Category GO:0034446 substrate adhesion-dependent cell spreading Database 0.26
Category members GO Category GO:0045296 cadherin binding Database 0.26
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0045295 gamma-catenin binding Database 0.23
Category members GO Category GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase Database 0.21
Category members GO Category GO:0030838 positive regulation of actin filament polymerization Database 0.21
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0031234 extrinsic to cytoplasmic side of plasma membrane Database 0.1
Category members GO Category GO:0006935 chemotaxis Database 0.09
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0001932 regulation of protein phosphorylation Database 0.04
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0010762 regulation of fibroblast migration Database 0.03
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_500 PID_FCER1_PATHWAY 0 0
Category members Pathway Pathway_522 PID_KIT_PATHWAY 0 0
Category members Pathway Pathway_602 PID_PTP1B_PATHWAY 0 0
Category members GO Category GO:0004715 non-membrane spanning protein tyrosine kinase activity Database 0
Category members GO Category GO:0005154 epidermal growth factor receptor binding Database 0
Category members GO Category GO:0007155 cell adhesion Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0008157 protein phosphatase 1 binding Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0008289 lipid binding Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0
Category members GO Category GO:0018108 peptidyl-tyrosine phosphorylation Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0030335 positive regulation of cell migration Database 0
Category members GO Category GO:0034614 cellular response to reactive oxygen species Database 0
Category members GO Category GO:0035426 extracellular matrix-cell signaling Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0
Category members GO Category GO:0036006 cellular response to macrophage colony-stimulating factor stimulus Database 0
Category members GO Category GO:0042503 tyrosine phosphorylation of Stat3 protein Database 0
Category members GO Category GO:0048008 platelet-derived growth factor receptor signaling pathway Database 0
Category members GO Category GO:0050839 cell adhesion molecule binding Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0
Category members GO Category GO:0070102 interleukin-6-mediated signaling pathway Database 0


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