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BIOCARTA_IL10_PATHWAY
(Pathway_749)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
STAT6 1 2.310 -1.150 -0.421 -0.069
HMOX1 0 0.330 0.220 -1.817 -1.289
BLVRA 0 -0.020 -0.040
STAT1 0 -0.550 0.170
JAK1 0 0.190 -0.100 -1.504 -0.381 -0.438
STAT3 0 0.200 -1.270 0.334
STAT5B 0 0.670 -0.960

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BLVRA Ubiquitylation K210 0.442 _MTVCLETEKK(gl)_
BLVRA Ubiquitylation K253 -0.092 _NIFLK(gl)DQNIFVQK_
BLVRA Ubiquitylation K269 -0.232 -0.059 _LLGQFSEK(gl)ELAAEK_
HMOX1 Ubiquitylation K243 -0.972 _ASNK(gl)VQDSAPVETPR_
HMOX1 Ubiquitylation K256 -1.769 _GK(gl)PPLNTR_
JAK1 Ubiquitylation K227 -0.405 _YIPETLNK(gl)SIR_
JAK1 Ubiquitylation K249 0.116 0.771 _DFLK(gl)EFNNK_
JAK1 Ubiquitylation K559 -0.478 _EISNLLVATK(gl)K_
STAT1 Phosphorylation S727 1.377 0.974 _LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3 Ubiquitylation K177 0.957 _VVENLQDDFDFNYK(gl)TLK_
STAT3 Ubiquitylation K180 1.179 _TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3 Ubiquitylation K244 0.262 _TLTDEELADWK(gl)R_
STAT3 Phosphorylation T714 -0.338 _FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3 Phosphorylation S727 -0.079 0.156 _FICVTPTTCSNTIDLPMS(ph)PR_
STAT5B Phosphorylation S194 0.270 _IQAQFGPLAQLS(ph)PQER_


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