RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
GNAI3	1	0.750	-0.890
GNAI3	1	0.750	-0.890	0.217			-0.334	-0.374
GNAO1	1	1.200	-1.320
PIK3R2	1	2.740	-1.180				0.269	0.348
PLCG1	1	-0.170	0.000
KRAS	1	-0.510	0.620				1.031	0.887
KRAS	1	-0.510	0.620				0.246	-0.346
TLN1	1	-0.130	0.000	0.807			0.246	0.137
NRAS	1	1.810	-0.720				0.246	-0.346
PIK3CB	0	-1.390	2.350
PIK3CB	0	-0.710	1.450
GNAI1	0	-0.580	0.990
GNAI2	0	0.190	-0.520
GNAL	0	1.660	-1.170
GNAS	0	0.840	-0.750
GNAT1	0	-0.110	-0.270
GNAT2	0	0.140	-0.880
GNAT3	0	1.110	-0.500
NCK2	0	-0.870	1.530
MAPK3	0
WASL	0	-0.430	0.380
GAB1	0	1.950	-1.110
STAT1	0	-0.550	0.170
SOS1	0	0.500	-0.620	-0.570
PIK3R3	0	-0.140	-0.480
PIK3R3	0	-0.140	-0.480				-0.441	0.147
PIK3CA	0
GNAI1	0	-0.580	0.990	0.116			-0.747
PIK3R1	0	1.910	-1.220				-0.441	0.147
EGFR	0	-0.580	0.520				0.513	0.090
GSN	0	0.350	-0.590
PAK1	0	1.190	-0.630
NCK1	0	-0.370	0.580
STAT3	0	0.200	-1.270					0.334
HRAS	0	1.470	-0.520
GRB2	0	-0.240	0.300		-1.021	0.057	0.906
PTPN11	0	-0.210	-0.400	0.644			1.053	0.451
PTPN1	0	-0.150	0.310	1.066	0.459	0.251	0.322	0.379
SRC	0	0.050	0.470	-0.031

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
EGFR	Phosphorylation	T693	0.486	-0.139	_ELVEPLT(ph)PSGEAPNQALLR_
EGFR	Phosphorylation	S991		-0.041	_MHLPS(ph)PTDSNFYR_
GAB1	Phosphorylation	S266	0.756	0.551	_SYS(ph)HDVLPK_
GAB1	Phosphorylation	S367	0.230	0.176	_TAS(ph)DTDSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	T369		-0.352	_TASDT(ph)DSSYCIPTAGMS(ph)PSR_
GAB1	Phosphorylation	S381	-0.481	0.139	_TASDTDSSYCIPTAGM(ox)S(ph)PSR_
GAB1	Phosphorylation	S401	0.266	0.788	_DAS(ph)SQDCYDIPR_
GAB1	Phosphorylation	S402	0.328	0.633	_DASS(ph)QDCYDIPR_
GAB1	Phosphorylation	S419		0.540	_SSS(ph)LEGFHNHFK_
GNAI1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI1	Ubiquitylation	K92	0.873	0.567	_LK(gl)IDFGDSAR_
GNAI2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K29	0.529	-0.094	_NLREDGEK(gl)AAK_
GNAI3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAI3	Ubiquitylation	K92	1.569		_LK(gl)IDFGEAAR_
GNAI3	Ubiquitylation	K349	-0.221	-0.339	_NNLK(gl)ECGLY_
GNAL	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAO1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAS	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT1	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT2	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GNAT3	Ubiquitylation	K53	-1.168	-0.413	_LLLLGAGESGK(gl)STIVK_
GRB2	Ubiquitylation	K10	0.146		_YDFK(gl)ATADDELSFK_
GRB2	Ubiquitylation	K20	-0.078		_ATADDELSFK(gl)R_
GRB2	Ubiquitylation	K69	-0.362	0.641	_AK(gl)AEEMLSK_
GRB2	Ubiquitylation	K76	0.754		_AEEMLSK(gl)QR_
GRB2	Ubiquitylation	K109	0.381	-0.002	_FGNDVQHFK(gl)VLR_
GSN	Ubiquitylation	K360	-0.879	0.993	_AALK(gl)TASDFITK_
HRAS	Ubiquitylation	K170	-1.005		_K(gl)LNPPDESGPGCMSCK_
KRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
KRAS	Ubiquitylation	K235	0.591	0.087	_TVDTK(gl)QAQDLAR_
KRAS	Ubiquitylation	K254	-0.450	-0.156	_SYGIPFIETSAK(gl)TR_
MAPK3	Phosphorylation	Y204	-0.807	-2.487	_IADPEHDHTGFLTEY(ph)VATR_
MAPK3	Ubiquitylation	K289		-0.608	_NYLQSLPSKTK(gl)_
NCK1	Phosphorylation	S85	-0.027	-0.877	_RKPS(ph)VPDSASPADDSFVDPGER_
NCK1	Phosphorylation	S91		0.493	_RKPSVPDSAS(ph)PADDSFVDPGER_
NCK2	Phosphorylation	S90	-0.317	0.054	_DAS(ph)PTPSTDAEYPANGSGADR_
NRAS	Ubiquitylation	K128	1.528	1.433	_TVDTK(gl)QAHELAK_
PAK1	Phosphorylation	S174	-1.439	-0.597	_AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1	Phosphorylation	T212		0.312	_SVIEPLPVT(ph)PTR_
PAK1	Phosphorylation	T219	-0.560	-0.962	_DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1	Phosphorylation	S220	-0.916	-0.774	_DVATS(ph)PISPTENNTTPPDALTR_
PAK1	Phosphorylation	S223	1.033	0.153	_DVATSPIS(ph)PTENNTTPPDALTR_
PAK1	Phosphorylation	T225	-1.278		_DVATSPISPT(ph)ENNTTPPDALTR_
PAK1	Phosphorylation	T230	-1.418	-1.502	_DVATSPISPTENNTT(ph)PPDALTR_
PIK3CA	Ubiquitylation	K864	0.390	0.588	_NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA	Ubiquitylation	K868	0.204	0.651	_NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA	Ubiquitylation	K974	-0.273		_GAQECTK(gl)TREFER_
PIK3CB	Ubiquitylation	K1044		0.990	_SEEEALKQFKQK(gl)_
PIK3R2	Phosphorylation	S262		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Phosphorylation	S263		-2.237	_APPPPS(ph)SPPPGGAPDGSEPSPDFPALLVEK_
PIK3R2	Ubiquitylation	K500	-0.189		_IFEEQGQTQEK(gl)CSK_
PIK3R2	Ubiquitylation	K541	-0.609		_TK(gl)LEQQLR_
PIK3R2	Ubiquitylation	K564	-0.431	-1.022	_MNSLK(gl)PDLMQLR_
PIK3R3	Ubiquitylation	K226		-0.376	_YQQDQLVKEDNIDAVGKK(gl)_
PIK3R3	Ubiquitylation	K320		0.385	_LGEIHDSK(gl)MR_
PLCG1	Ubiquitylation	K300		8.031	_DLK(gl)NMLSQVNYR_
PLCG1	Ubiquitylation	K348		-0.219	_SLMYSAQK(gl)TMDLPFLEASTLR_
PLCG1	Ubiquitylation	K552		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K553		-0.355	_NMAQYFK(gl)K_
PLCG1	Ubiquitylation	K1063	0.864	0.355	_LTEGK(gl)IMER_
PLCG1	Phosphorylation	S1370	0.475	0.515	_AREGS(ph)FESR_
PTPN1	Phosphorylation	S352		0.032	_GS(ph)PLNAAPYGIESMSQDTEVR_
PTPN1	Phosphorylation	S365	-0.247	0.956	_GSPLNAAPYGIESMS(ph)QDTEVR_
PTPN1	Phosphorylation	S378	1.462	1.262	_VVGGS(ph)LR_
PTPN11	Ubiquitylation	K124	0.562		_EAEK(gl)LLTEK_
SOS1	Phosphorylation	S1082	0.278		_IPESETESTASAPNS(ph)PR_
SOS1	Phosphorylation	S1166	0.097	-0.094	_RPESAPAES(ph)SPSK_
SRC	Phosphorylation	S17	-0.604	-0.689	_S(ph)LEPAENVHGAGGGAFPASQTPSKPASADGHR_
SRC	Phosphorylation	S75	0.060	0.331	_LFGGFNSSDTVTS(ph)PQR_
STAT1	Phosphorylation	S727	1.377	0.974	_LQTTDNLLPMS(ph)PEEFDEVSR_
STAT3	Ubiquitylation	K177	0.957		_VVENLQDDFDFNYK(gl)TLK_
STAT3	Ubiquitylation	K180	1.179		_TLK(gl)SQGDMQDLNGNNQSVTR_
STAT3	Ubiquitylation	K244	0.262		_TLTDEELADWK(gl)R_
STAT3	Phosphorylation	T714		-0.338	_FICVT(ph)PTTCSNTIDLPMS(ph)PR_
STAT3	Phosphorylation	S727	-0.079	0.156	_FICVTPTTCSNTIDLPMS(ph)PR_
TLN1	Ubiquitylation	K334	-0.489	0.561	_LLGITK(gl)ECVM(ox)R_
TLN1	Phosphorylation	S423		0.105	_DHFGLEGDEESTMLEDS(ph)VSPKK_
TLN1	Phosphorylation	S425	-0.366	-0.322	_DHFGLEGDEESTMLEDSVS(ph)PKK_
TLN1	Ubiquitylation	K869	-0.260		_ILADATAK(gl)MVEAAK_
TLN1	Ubiquitylation	K1541	0.365	2.311	_EVANSTANLVK(gl)TIK_
TLN1	Ubiquitylation	K2021	0.309	0.479	_EGILK(gl)TAK_
WASL	Phosphorylation	S430	0.399	0.664	_VEQNSRPVS(ph)CSGR_
WASL	Phosphorylation	S432		1.141	_VEQNSRPVSCS(ph)GR_